STRINGSTRING
aksA aksA AJG96904.1 AJG96904.1 AJG96905.1 AJG96905.1 leuA_2 leuA_2 AJG96997.1 AJG96997.1 AJG97018.1 AJG97018.1 AJG97113.1 AJG97113.1 pyk_2 pyk_2 AJG97393.1 AJG97393.1 AJG97427.1 AJG97427.1 AJG97429.2 AJG97429.2 AJG97553.1 AJG97553.1 AJG97680.1 AJG97680.1 AJG97682.1 AJG97682.1 ldh-3 ldh-3 AJG97744.1 AJG97744.1 AJG97746.1 AJG97746.1 accD accD accA accA eutD eutD ackA ackA AJG97982.1 AJG97982.1 AJG98117.1 AJG98117.1 AJG98159.1 AJG98159.1 AJG98360.1 AJG98360.1 AJG98611.1 AJG98611.1 AJG98657.1 AJG98657.1 AJG98768.1 AJG98768.1 AJG98769.2 AJG98769.2 AJG98798.1 AJG98798.1 AJG99023.1 AJG99023.1 leuA_4 leuA_4 accB_2 accB_2 cfiB_2 cfiB_2 AJG99601.1 AJG99601.1 AJH00286.1 AJH00286.1 AJH00318.1 AJH00318.1 AJH00389.1 AJH00389.1 AJH00469.1 AJH00469.1 atoB atoB AJH00647.1 AJH00647.1 korB_1 korB_1 ydiF_4 ydiF_4 AJH01048.1 AJH01048.1 korB_2 korB_2 korA_2 korA_2 pduL pduL bssA_1 bssA_1 ldh ldh AJH01282.1 AJH01282.1 nifJ_3 nifJ_3 AJH01599.1 AJH01599.1 AJH01659.1 AJH01659.1 pyk_3 pyk_3 AJH02086.1 AJH02086.1 AJH02257.1 AJH02257.1 AMK50376.1 AMK50376.1 ldh-2 ldh-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aksAHomoaconitate hydratase; In Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa)
AJG96904.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AJG96905.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
leuA_2Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (531 aa)
AJG96997.1Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (860 aa)
AJG97018.1Pyruvate formate-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (784 aa)
AJG97113.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
pyk_2Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
AJG97393.1Glycyl radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (801 aa)
AJG97427.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa)
AJG97429.2Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (493 aa)
AJG97553.1Pyruvate, phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (875 aa)
AJG97680.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
AJG97682.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
ldh-3L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
AJG97744.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (171 aa)
AJG97746.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (272 aa)
eutDPhosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
AJG97982.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AJG98117.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (340 aa)
AJG98159.1Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1172 aa)
AJG98360.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AJG98611.1Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1171 aa)
AJG98657.1Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
AJG98768.1Isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AJG98769.2Homocitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (250 aa)
AJG98798.1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (518 aa)
AJG99023.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
leuA_42-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (667 aa)
accB_2acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
cfiB_2acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
AJG99601.1Lactate racemization operon protein LarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
AJH00286.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AJH00318.13-oxoacid CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (515 aa)
AJH00389.1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (514 aa)
AJH00469.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
atoBacetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
AJH00647.12-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
korB_12-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent decarboxylation of 2-oxoacids, such as pyruvate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ydiF_4CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (508 aa)
AJH01048.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
korB_22-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent decarboxylation of 2-oxoacids, such as pyruvate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
korA_22-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
pduLPhosphate propanoyltransferase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (212 aa)
bssA_1Glycyl radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (844 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
AJH01282.1Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
nifJ_3Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1169 aa)
AJH01599.13-oxoacid CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (517 aa)
AJH01659.13-oxoacid CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family. (516 aa)
pyk_3Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AJH02086.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa)
AJH02257.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AMK50376.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (466 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (315 aa)
Your Current Organism:
Clostridium beijerinckii
NCBI taxonomy Id: 1520
Other names: ATCC 25752, BCRC 14488, C. beijerinckii, CCUG 56442, CIP 104308, Clostridium rubrum, Clostridium sp. H18, DSM 791, LMG 5716, LMG:5716, NCIMB 9362, NCTC 13035
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.