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rlmJ rlmJ rsmD rsmD rimM rimM rlmH rlmH rsmA rsmA rng_2 rng_2 rluC_2 rluC_2 GCA_900177895_00634 GCA_900177895_00634 hrpB hrpB rluB rluB ybeY ybeY rsmE rsmE rsmH rsmH rsmB_1 rsmB_1 truC truC rlmN rlmN rluF rluF rsuA rsuA GCA_900177895_01021 GCA_900177895_01021 rlmE rlmE rsmB_2 rsmB_2 rsmJ rsmJ rlmB rlmB rluD rluD yqgF yqgF rnc rnc GCA_900177895_01513 GCA_900177895_01513 rph rph rsmG rsmG rbfA rbfA rsmI_1 rsmI_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rlmJUnannotated protein; Specifically methylates the adenine in position 2030 of 23S rRNA. (280 aa)
rsmDUnannotated protein. (193 aa)
rimMUnannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (169 aa)
rlmHUnannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
rsmAUnannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (259 aa)
rng_2Unannotated protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (956 aa)
rluC_2Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (328 aa)
GCA_900177895_00634Unannotated protein. (877 aa)
hrpBUnannotated protein. (464 aa)
rluBUnannotated protein; Belongs to the pseudouridine synthase RsuA family. (362 aa)
ybeYUnannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (169 aa)
rsmEUnannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (241 aa)
rsmHUnannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (320 aa)
rsmB_1Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (420 aa)
truCUnannotated protein. (247 aa)
rlmNUnannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (363 aa)
rluFUnannotated protein; Belongs to the pseudouridine synthase RsuA family. (243 aa)
rsuAUnannotated protein; Belongs to the pseudouridine synthase RsuA family. (231 aa)
GCA_900177895_01021Unannotated protein. (98 aa)
rlmEUnannotated protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (206 aa)
rsmB_2Unannotated protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (418 aa)
rsmJUnannotated protein; Specifically methylates the guanosine in position 1516 of 16S rRNA. (245 aa)
rlmBUnannotated protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (257 aa)
rluDUnannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (366 aa)
yqgFUnannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (156 aa)
rncUnannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (235 aa)
GCA_900177895_01513Unannotated protein. (290 aa)
rphUnannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (241 aa)
rsmGUnannotated protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (213 aa)
rbfAUnannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (123 aa)
rsmI_1Unannotated protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (289 aa)
Your Current Organism:
Kingella negevensis
NCBI taxonomy Id: 1522312
Other names: CCUG 69806, CSUR P957, K. negevensis, Kingella negevensis El Houmami et al. 2017, Kingella sp. AA267, Kingella sp. AA503, Kingella sp. BB632, Kingella sp. BB713, Kingella sp. CC132, Kingella sp. CC173_6, Kingella sp. CC505b, Kingella sp. CC546, Kingella sp. CHUV31, Kingella sp. D2292, Kingella sp. D2756, Kingella sp. D7323, Kingella sp. EE451, Kingella sp. EPA009, Kingella sp. EPA014, Kingella sp. PED555, Kingella sp. PVC1712, Kingella sp. PVC1735, Kingella sp. SW7208426, Kingella sp. Sch1437, Kingella sp. Sch538, Kingella sp. Sch690, strain Sch538
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