STRINGSTRING
pgpB pgpB lpxB lpxB ispH ispH GCA_900177895_00141 GCA_900177895_00141 GCA_900177895_00213 GCA_900177895_00213 gpsA gpsA GCA_900177895_00318 GCA_900177895_00318 ispD ispD ispF ispF suhB_2 suhB_2 dgkA dgkA ispG ispG psd psd GCA_900177895_01316 GCA_900177895_01316 plsC_2 plsC_2 lpxH lpxH GCA_900177895_01387 GCA_900177895_01387 pgpA pgpA pgsA pgsA plsC_2-2 plsC_2-2 plsY plsY GCA_900177895_01767 GCA_900177895_01767 ispE ispE lpxK lpxK plsX plsX glmU glmU dxr dxr lpxD lpxD cdsA cdsA lpxA lpxA fabZ fabZ lpxC lpxC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgpBUnannotated protein. (260 aa)
lpxBUnannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
ispHUnannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa)
GCA_900177895_00141Unannotated protein. (219 aa)
GCA_900177895_00213Unannotated protein. (306 aa)
gpsAUnannotated protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa)
GCA_900177895_00318Unannotated protein. (224 aa)
ispDUnannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa)
ispFUnannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
suhB_2Unannotated protein; Belongs to the inositol monophosphatase superfamily. (264 aa)
dgkAUnannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa)
ispGUnannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (421 aa)
psdUnannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (298 aa)
GCA_900177895_01316Unannotated protein. (361 aa)
plsC_2Unannotated protein; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (265 aa)
lpxHUnannotated protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (247 aa)
GCA_900177895_01387Unannotated protein. (198 aa)
pgpAUnannotated protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (168 aa)
pgsAUnannotated protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (187 aa)
plsC_2-2Unannotated protein. (243 aa)
plsYUnannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (205 aa)
GCA_900177895_01767Unannotated protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (289 aa)
ispEUnannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (282 aa)
lpxKUnannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (351 aa)
plsXUnannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa)
glmUUnannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa)
dxrUnannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (390 aa)
lpxDUnannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (343 aa)
cdsAUnannotated protein; Belongs to the CDS family. (264 aa)
lpxAUnannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (259 aa)
fabZUnannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (175 aa)
lpxCUnannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (308 aa)
Your Current Organism:
Kingella negevensis
NCBI taxonomy Id: 1522312
Other names: CCUG 69806, CSUR P957, K. negevensis, Kingella negevensis El Houmami et al. 2017, Kingella sp. AA267, Kingella sp. AA503, Kingella sp. BB632, Kingella sp. BB713, Kingella sp. CC132, Kingella sp. CC173_6, Kingella sp. CC505b, Kingella sp. CC546, Kingella sp. CHUV31, Kingella sp. D2292, Kingella sp. D2756, Kingella sp. D7323, Kingella sp. EE451, Kingella sp. EPA009, Kingella sp. EPA014, Kingella sp. PED555, Kingella sp. PVC1712, Kingella sp. PVC1735, Kingella sp. SW7208426, Kingella sp. Sch1437, Kingella sp. Sch538, Kingella sp. Sch690, strain Sch538
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