STRINGSTRING
AOO79095.1 AOO79095.1 AOO79097.1 AOO79097.1 AOO79544.1 AOO79544.1 AOO79623.1 AOO79623.1 AOO79722.1 AOO79722.1 AOO79970.1 AOO79970.1 AOO80766.1 AOO80766.1 AOO80772.1 AOO80772.1 AOO80796.1 AOO80796.1 AOO81008.1 AOO81008.1 AOO81012.1 AOO81012.1 ilvD ilvD AOO81712.1 AOO81712.1 ilvD-2 ilvD-2 AOO84692.1 AOO84692.1 leuA leuA ilvC ilvC AOO83244.1 AOO83244.1 AOO83247.1 AOO83247.1 AOO83268.1 AOO83268.1 AOO83276.1 AOO83276.1 lldD lldD leuB leuB leuC leuC leuD leuD ilvE ilvE AOO83672.1 AOO83672.1 AOO83920.1 AOO83920.1 leuC-2 leuC-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOO79095.13-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AOO79097.1Branched-chain amino acid--2-keto-4-methylthiobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
AOO79544.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (607 aa)
AOO79623.1Acetolactate synthase; Catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (551 aa)
AOO79722.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (570 aa)
AOO79970.1Alpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AOO80766.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (563 aa)
AOO80772.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (541 aa)
AOO80796.1Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
AOO81008.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AOO81012.1Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (613 aa)
AOO81712.1Citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)
ilvD-2Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (576 aa)
AOO84692.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (522 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AOO83244.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
AOO83247.1Acetolactate synthase 3 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
AOO83268.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
AOO83276.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
lldDAlpha-hydroxy-acid oxidizing enzyme; Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (369 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (295 aa)
AOO83672.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (577 aa)
AOO83920.13-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (205 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (480 aa)
Your Current Organism:
Bosea vaviloviae
NCBI taxonomy Id: 1526658
Other names: B. vaviloviae, Bosea sp. Vaf-17, Bosea sp. Vaf-18, Bosea sp. Vaf-43, Bosea vaviloviae Safronova et al. 2015, LMG 28367, LMG:28367, RCAM 02129, strain Vaf-18, strain Vaf18
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