STRINGSTRING
AIL66092.1 AIL66092.1 AIL64424.1 AIL64424.1 AIL64470.1 AIL64470.1 AIL64539.1 AIL64539.1 AIL64631.1 AIL64631.1 AIL64632.1 AIL64632.1 AIL64633.1 AIL64633.1 AIL64639.1 AIL64639.1 AIL64656.1 AIL64656.1 infB infB AIL64672.1 AIL64672.1 AIL64682.1 AIL64682.1 AIL64730.1 AIL64730.1 rpsA rpsA dnaC dnaC AIL64798.1 AIL64798.1 rpsO rpsO AIL64855.1 AIL64855.1 AIL64877.1 AIL64877.1 rpmI rpmI rplL rplL rplJ rplJ rpsG rpsG AIL64942.1 AIL64942.1 rpmG rpmG rpsP rpsP rpsU rpsU rpsB rpsB AIL65081.1 AIL65081.1 rpmA rpmA AIL65151.1 AIL65151.1 AIL65190.1 AIL65190.1 recF recF nth nth rplM rplM rpsI rpsI parB parB rpmF rpmF dnaQ dnaQ rpmB rpmB rpmE rpmE rpsF rpsF rpsR rpsR rplI rplI AIL65399.1 AIL65399.1 guaB guaB AIL65509.1 AIL65509.1 rpmJ2 rpmJ2 AIL66128.2 AIL66128.2 rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpsK rpsK rplQ rplQ dnaG dnaG recO recO AIL65687.1 AIL65687.1 ydfG ydfG AIL66122.1 AIL66122.1 recR recR AIL65699.1 AIL65699.1 recN recN hupB hupB rplY rplY rpsD rpsD AIL65829.1 AIL65829.1 AIL65861.1 AIL65861.1 rarA_2 rarA_2 AIL65921.1 AIL65921.1 rpsT rpsT dnaA dnaA traC traC AIL66025.1 AIL66025.1 AIL66066.1 AIL66066.1 priA priA AIL66090.1 AIL66090.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIL66092.1Ankyrin repeat protein. (188 aa)
AIL64424.1Ankyrin repeat protein. (610 aa)
AIL64470.1Deoxycytidylate deaminase. (158 aa)
AIL64539.1Hypothetical protein. (350 aa)
AIL64631.1Ankyrin repeat protein. (444 aa)
AIL64632.1Ankyrin repeat protein. (374 aa)
AIL64633.1Ankyrin repeat protein. (356 aa)
AIL64639.1Hypothetical protein. (303 aa)
AIL64656.1Ankyrin repeat protein. (637 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (853 aa)
AIL64672.1Tetratricopeptide repeat protein. (140 aa)
AIL64682.1DnaA regulatory inactivator Hda; Belongs to the DnaA family. (222 aa)
AIL64730.1Tetratricopeptide repeat protein. (446 aa)
rpsARibosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (583 aa)
dnaCReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (500 aa)
AIL64798.1Hypothetical protein. (99 aa)
rpsORibosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
AIL64855.1Putative DEAD-box ATP-dependent RNA helicase. (366 aa)
AIL64877.1Ribosome-associated inhibitor A. (120 aa)
rpmIRibosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (67 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (124 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (170 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
AIL64942.1Hypothetical protein; Belongs to the UPF0758 family. (229 aa)
rpmGRibosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (83 aa)
rpsURibosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (71 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (284 aa)
AIL65081.1Ankyrin repeat protein; Via S4TE changed from Uroporphyrinogen-III decarboxylase. (311 aa)
rpmARibosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (87 aa)
AIL65151.1Periplasmic protein TonB. (307 aa)
AIL65190.1Biotin biosynthesis protein BioC. (335 aa)
recFDNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (373 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (157 aa)
rpsIRibosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (151 aa)
parBChromosome-partitioning protein ParB; Belongs to the ParB family. (282 aa)
rpmFRibosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (60 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (226 aa)
rpmBRibosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (102 aa)
rpmERibosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. (84 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (121 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (92 aa)
rplIRibosomal protein L9; Binds to the 23S rRNA. (154 aa)
AIL65399.1Flp pilus assembly protein TadD, contains TPR repeat. (276 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
AIL65509.1Ankyrin repeat protein. (820 aa)
rpmJ250S ribosomal protein L36 2; Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
AIL66128.2Hypothetical protein. (463 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (226 aa)
rplDRibosomal protein L4; Forms part of the polypeptide exit tunnel. (206 aa)
rplWRibosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (275 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVRibosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (125 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (219 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa)
rpmCRibosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (70 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (76 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (106 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa)
rpsNRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (123 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (184 aa)
rpmD50S ribosomal protein L30. (67 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (158 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa)
rplQRibosomal protein L17. (141 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (601 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (243 aa)
AIL65687.1Ankyrin repeat protein. (971 aa)
ydfGNADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
AIL66122.1Hypothetical protein. (613 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
AIL65699.1YbaB/EbfC family DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (100 aa)
recNRecombination protein N; May be involved in recombinational repair of damaged DNA. (552 aa)
hupBDNA-binding protein HRm; Belongs to the bacterial histone-like protein family. (112 aa)
rplYRibosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (204 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
AIL65829.1Ankyrin repeat protein. (918 aa)
AIL65861.1Ankyrin repeat protein. (485 aa)
rarA_2Replication-associated recombination protein A. (282 aa)
AIL65921.1Ankyrin repeat protein. (399 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (466 aa)
traCDNA primase TraC. (319 aa)
AIL66025.1PAS fold protein. (307 aa)
AIL66066.1Ankyrin repeat protein. (269 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (744 aa)
AIL66090.1Ankyrin repeat protein. (375 aa)
Your Current Organism:
Rickettsiales bacterium Ac37b
NCBI taxonomy Id: 1528098
Other names: R. bacterium Ac37b
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