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thrB thrB hom hom metE metE cysE cysE cysK1 cysK1 ALE18872.1 ALE18872.1 ALE19144.1 ALE19144.1 cysS cysS metXA metXA ALE19235.1 ALE19235.1 ALE19236.1 ALE19236.1 ALE19709.1 ALE19709.1 ahcY ahcY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (301 aa)
homHomoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (771 aa)
cysESerine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
cysK1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
ALE18872.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
ALE19144.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa)
metXAHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (368 aa)
ALE19235.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
ALE19236.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
ALE19709.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (501 aa)
Your Current Organism:
Lawsonella clevelandensis
NCBI taxonomy Id: 1528099
Other names: CCUG 66657, Corynebacteriales bacterium CCF1, Corynebacteriales bacterium CCF2, Corynebacteriales bacterium X1036, Corynebacteriales bacterium X1698, Corynebacterineae bacterium NML 120705, Corynebacterineae bacterium X1698, DSM 45743, L. clevelandensis, Lawsonella clevelandensis Bell et al. 2016, bacterium CCF-01, strain X1036
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