STRINGSTRING
ALE19542.1 ALE19542.1 ALE18493.1 ALE18493.1 sigA sigA ruvB ruvB ALE18424.1 ALE18424.1 ALE19510.1 ALE19510.1 argR argR ALE19468.1 ALE19468.1 ALE19456.1 ALE19456.1 ogt ogt ALE19398.1 ALE19398.1 smtB smtB hrcA hrcA ALE19278.1 ALE19278.1 mtrA mtrA walR walR tcrX tcrX ALE19683.1 ALE19683.1 ALE19129.1 ALE19129.1 ALE19092.1 ALE19092.1 ALE19007.1 ALE19007.1 ytrA ytrA regX3 regX3 ramA ramA mprA mprA ALE19577.1 ALE19577.1 yiaJ yiaJ ftsK ftsK recX recX iclR iclR lexA lexA ideR ideR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALE19542.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (316 aa)
ALE18493.1RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (325 aa)
sigAHypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (598 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (375 aa)
ALE18424.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
ALE19510.1Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (232 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (174 aa)
ALE19468.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
ALE19456.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
ogtHypothetical protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (185 aa)
ALE19398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
smtBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
hrcAHrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (346 aa)
ALE19278.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa)
mtrATranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
walRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
tcrXAlkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ALE19683.1Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ALE19129.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (173 aa)
ALE19092.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
ALE19007.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
ytrAGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
regX3XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
ramAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
mprATranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
ALE19577.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
yiaJIclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
ftsKCell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FtsK/SpoIIIE/SftA family. (784 aa)
recXHypothetical protein; Modulates RecA activity; Belongs to the RecX family. (179 aa)
iclRIclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
lexAArsR family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (225 aa)
ideRHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
Your Current Organism:
Lawsonella clevelandensis
NCBI taxonomy Id: 1528099
Other names: CCUG 66657, Corynebacteriales bacterium CCF1, Corynebacteriales bacterium CCF2, Corynebacteriales bacterium X1036, Corynebacteriales bacterium X1698, Corynebacterineae bacterium NML 120705, Corynebacterineae bacterium X1698, DSM 45743, L. clevelandensis, Lawsonella clevelandensis Bell et al. 2016, bacterium CCF-01, strain X1036
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