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purQ purQ murI murI murD murD murC murC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (225 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (301 aa)
murDHypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (485 aa)
Your Current Organism:
Lawsonella clevelandensis
NCBI taxonomy Id: 1528099
Other names: CCUG 66657, Corynebacteriales bacterium CCF1, Corynebacteriales bacterium CCF2, Corynebacteriales bacterium X1036, Corynebacteriales bacterium X1698, Corynebacterineae bacterium NML 120705, Corynebacterineae bacterium X1698, DSM 45743, L. clevelandensis, Lawsonella clevelandensis Bell et al. 2016, bacterium CCF-01, strain X1036
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