(23 nodes) Purine metabolism network (Theileria equi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	BEWA_017730	Phosphoribosyl transferase domain containing protein. (189 aa)
	BEWA_018620	Pyruvate kinase, putative. (701 aa)
	BEWA_017710	Pribosyltran domain-containing protein. (510 aa)
	BEWA_019170	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
	BEWA_021630	Nucleoside diphosphate kinase, putative; Belongs to the NDK family. (149 aa)
	BEWA_023810	Guanylate kinase, putative. (194 aa)
	BEWA_025130	UMP-CMP kinase, putative; Belongs to the adenylate kinase family. (199 aa)
	BEWA_000250	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (566 aa)
	BEWA_001280	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family. (450 aa)
	BEWA_005670	Bis5'-nucleosyl-tetraphosphatase, putative. (144 aa)
	BEWA_007100	Pyruvate kinase; Belongs to the pyruvate kinase family. (515 aa)
	BEWA_045860	Adenylate kinase, putative; Belongs to the adenylate kinase family. (245 aa)
	BEWA_050750	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (502 aa)
	BEWA_012000	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (857 aa)
	BEWA_052260	Adenylosuccinate lyase, putative. (459 aa)
	BEWA_052910	Uncharacterized protein; Belongs to the HAM1 NTPase family. (182 aa)
	BEWA_037380	3',5' cyclic nucleotide phosphodiesterase, putative; Belongs to the cyclic nucleotide phosphodiesterase family. (510 aa)
	BEWA_037980	Ribonucleoside-diphosphate reductase small chain, putative. (335 aa)
	BEWA_038690	Phosphoribosyl transferase domain containing protein. (187 aa)
	BEWA_040250	GMP synthase, putative. (522 aa)
	BEWA_041490	Adenylate kinase, putative; Belongs to the adenylate kinase family. (238 aa)
	BEWA_044190	Phosphodiesterase. (516 aa)
	BEWA_044240	Ribonucleoside-diphosphate reductase small chain, putative. (327 aa)

Your Current Organism:

Theileria equi

NCBI taxonomy Id: 1537102
Other names: Babesia equi WA, Babesia equi strain WA, T. equi strain WA, Theileria equi strain WA

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEWA_000250	BEWA_001280	L0B037	L0B0C8	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family.	0.832
BEWA_000250	BEWA_005670	L0B037	L0B1Z9	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Bis5'-nucleosyl-tetraphosphatase, putative.	0.974
BEWA_000250	BEWA_007100	L0B037	L0B227	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.415
BEWA_000250	BEWA_012000	L0B037	L1LBD4	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.676
BEWA_000250	BEWA_017710	L0B037	L0ATR6	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Pribosyltran domain-containing protein.	0.700
BEWA_000250	BEWA_017730	L0B037	L0ATG8	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Phosphoribosyl transferase domain containing protein.	0.626
BEWA_000250	BEWA_018620	L0B037	L0ATP6	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Pyruvate kinase, putative.	0.415
BEWA_000250	BEWA_021630	L0B037	L0AUU2	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase, putative; Belongs to the NDK family.	0.991
BEWA_000250	BEWA_023810	L0B037	L0AV94	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Guanylate kinase, putative.	0.764
BEWA_000250	BEWA_025130	L0B037	L0AXM8	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	UMP-CMP kinase, putative; Belongs to the adenylate kinase family.	0.784
BEWA_000250	BEWA_038690	L0B037	L1LER7	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Phosphoribosyl transferase domain containing protein.	0.626
BEWA_000250	BEWA_040250	L0B037	L1LEW5	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	GMP synthase, putative.	0.963
BEWA_000250	BEWA_041490	L0B037	L1LFI0	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Adenylate kinase, putative; Belongs to the adenylate kinase family.	0.732
BEWA_000250	BEWA_045860	L0B037	L1L9M5	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Adenylate kinase, putative; Belongs to the adenylate kinase family.	0.732
BEWA_000250	BEWA_050750	L0B037	L1LAX3	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.731
BEWA_000250	BEWA_052260	L0B037	L1LCV1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Adenylosuccinate lyase, putative.	0.784
BEWA_000250	BEWA_052910	L0B037	L1LD23	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Uncharacterized protein; Belongs to the HAM1 NTPase family.	0.895
BEWA_001280	BEWA_000250	L0B0C8	L0B037	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.832
BEWA_001280	BEWA_007100	L0B0C8	L0B227	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.501
BEWA_001280	BEWA_012000	L0B0C8	L1LBD4	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.590