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FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (746 aa) | ||||
BEWA_018800 | DNA repair protein rad50, putative. (1123 aa) | ||||
BEWA_003610 | Uncharacterized protein. (83 aa) | ||||
BEWA_007810 | DNA-repair protein xp-G, putative. (839 aa) | ||||
BEWA_003590 | XPG I domain-containing protein. (582 aa) | ||||
BEWA_006970 | DNA repair mre11 domain-containing protein. (871 aa) | ||||
BEWA_014260 | ERCC4 domain-containing protein. (738 aa) | ||||
BEWA_039940 | XPGI domain-containing protein. (314 aa) |