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BEWA_010730 BEWA_010730 BEWA_010460 BEWA_010460 BEWA_050400 BEWA_050400 NTH1 NTH1 BEWA_012300 BEWA_012300 BEWA_050410 BEWA_050410 BEWA_014260 BEWA_014260 BEWA_011920 BEWA_011920 BEWA_012520 BEWA_012520 BEWA_014140 BEWA_014140 BEWA_033190 BEWA_033190 BEWA_039350 BEWA_039350 BEWA_037400 BEWA_037400 BEWA_038290 BEWA_038290 BEWA_037430 BEWA_037430 FEN1 FEN1 BEWA_053580 BEWA_053580 BEWA_054210 BEWA_054210 BEWA_053750 BEWA_053750 BEWA_034930 BEWA_034930 BEWA_052950 BEWA_052950 MCM7 MCM7 BEWA_026800 BEWA_026800 BEWA_026820 BEWA_026820 BEWA_022620 BEWA_022620 BEWA_022570 BEWA_022570 BEWA_022040 BEWA_022040 BEWA_023010 BEWA_023010 BEWA_022910 BEWA_022910 BEWA_020580 BEWA_020580 BEWA_020470 BEWA_020470 BEWA_018350 BEWA_018350 BEWA_021140 BEWA_021140 BEWA_018800 BEWA_018800 BEWA_019120 BEWA_019120 BEWA_018720 BEWA_018720 BEWA_014940 BEWA_014940 BEWA_013270 BEWA_013270 BEWA_009400 BEWA_009400 BEWA_008210 BEWA_008210 BEWA_008580 BEWA_008580 BEWA_011430 BEWA_011430 BEWA_006970 BEWA_006970 BEWA_003590 BEWA_003590 BEWA_009190 BEWA_009190 BEWA_001310 BEWA_001310 BEWA_002080 BEWA_002080 BEWA_007810 BEWA_007810 BEWA_032270 BEWA_032270 BEWA_003610 BEWA_003610 BEWA_034460 BEWA_034460 BEWA_002890 BEWA_002890 BEWA_001440 BEWA_001440 BEWA_028330 BEWA_028330 BEWA_029560 BEWA_029560 BEWA_000720 BEWA_000720 BEWA_034450 BEWA_034450 BEWA_034070 BEWA_034070 BEWA_030610 BEWA_030610 BEWA_029580 BEWA_029580 BEWA_032500 BEWA_032500 BEWA_043350 BEWA_043350 BEWA_041610 BEWA_041610 BEWA_043420 BEWA_043420 BEWA_037970 BEWA_037970 BEWA_041170 BEWA_041170 BEWA_007040 BEWA_007040 BEWA_040770 BEWA_040770 BEWA_039940 BEWA_039940 BEWA_008140 BEWA_008140
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BEWA_010730DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2293 aa)
BEWA_010460DNA repair helicase, putative. (956 aa)
BEWA_050400DNA polymerase. (1356 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (666 aa)
BEWA_012300DNA mismatch repair protein, putative. (757 aa)
BEWA_050410DNA polymerase alpha catalytic subunit, putative. (755 aa)
BEWA_014260ERCC4 domain-containing protein. (738 aa)
BEWA_011920Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1053 aa)
BEWA_012520DNA ligase. (709 aa)
BEWA_014140ERCC4 domain-containing protein. (1091 aa)
BEWA_033190DNA repair helicase rad3/xp-D, putative. (851 aa)
BEWA_039350Recombinational repair protein, putative. (1841 aa)
BEWA_037400DNA replication licensing factor family protein; Belongs to the MCM family. (423 aa)
BEWA_038290DNA mismatch repair protein MLH1, putative. (737 aa)
BEWA_037430DNA replication licensing factor MCM5, putative; Belongs to the MCM family. (778 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (746 aa)
BEWA_053580HELICc2 domain-containing protein. (169 aa)
BEWA_054210Replication factor C subunit 1. (962 aa)
BEWA_053750Helicase ATP-binding domain-containing protein. (822 aa)
BEWA_034930GBP domain-containing protein. (908 aa)
BEWA_052950DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (622 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (681 aa)
BEWA_026800Uncharacterized protein. (131 aa)
BEWA_026820DNA gyrase subunit A, putative. (839 aa)
BEWA_022620ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (809 aa)
BEWA_022570HSA domain-containing protein. (802 aa)
BEWA_022040DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1170 aa)
BEWA_0230105'-3' exonuclease, putative. (437 aa)
BEWA_022910DNA helicase; Belongs to the MCM family. (961 aa)
BEWA_020580Helicase ATP-binding domain-containing protein. (1094 aa)
BEWA_020470Apurinic/apyrimidinic endonuclease, putative. (357 aa)
BEWA_018350DNA helicase; Belongs to the MCM family. (919 aa)
BEWA_021140Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (284 aa)
BEWA_018800DNA repair protein rad50, putative. (1123 aa)
BEWA_019120DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (807 aa)
BEWA_018720Rad25/xp-B DNA repair helicase, putative. (779 aa)
BEWA_014940Structural maintenance of chromosomes protein. (1198 aa)
BEWA_013270RuvB-like helicase; Belongs to the RuvB family. (472 aa)
BEWA_009400RuvB-like helicase; Belongs to the RuvB family. (494 aa)
BEWA_008210DNA replication licensing factor family member; Belongs to the MCM family. (901 aa)
BEWA_008580Rad51 domain-containing protein. (202 aa)
BEWA_011430Helicase family member protein. (784 aa)
BEWA_006970DNA repair mre11 domain-containing protein. (871 aa)
BEWA_003590XPG I domain-containing protein. (582 aa)
BEWA_009190Uncharacterized protein. (175 aa)
BEWA_001310Helicase family member protein. (857 aa)
BEWA_002080Uncharacterized protein. (137 aa)
BEWA_007810DNA-repair protein xp-G, putative. (839 aa)
BEWA_032270DUF2220 domain-containing protein. (223 aa)
BEWA_003610Uncharacterized protein. (83 aa)
BEWA_034460Membrane protein, putative. (118 aa)
BEWA_002890Helicase family member protein. (848 aa)
BEWA_001440DEAD/DEAH box helicase domain-containing protein. (1878 aa)
BEWA_028330DNA replication licensing factor MCM3, putative; Belongs to the MCM family. (931 aa)
BEWA_029560MUTSd domain-containing protein. (1456 aa)
BEWA_000720DNA replication licensing factor MCM4, putative; Belongs to the MCM family. (764 aa)
BEWA_034450Uncharacterized protein. (90 aa)
BEWA_034070Uncharacterized protein. (348 aa)
BEWA_030610DNA polymerase I family member protein. (1713 aa)
BEWA_029580MutS domain V containing protein. (200 aa)
BEWA_032500DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1173 aa)
BEWA_043350Helicase family member protein. (1430 aa)
BEWA_0416108-oxoguanine DNA-glycosylase, putative. (293 aa)
BEWA_043420DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (831 aa)
BEWA_037970DNA_MISMATCH_REPAIR_2 domain-containing protein. (1103 aa)
BEWA_041170Helicase family member protein. (932 aa)
BEWA_007040Helicase family member protein. (1736 aa)
BEWA_040770DNA polymerase. (1030 aa)
BEWA_039940XPGI domain-containing protein. (314 aa)
BEWA_008140ATP-dependent DNA helicase, RecQ family member protein. (1077 aa)
Your Current Organism:
Theileria equi
NCBI taxonomy Id: 1537102
Other names: Babesia equi WA, Babesia equi strain WA, T. equi strain WA, Theileria equi strain WA
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