STRINGSTRING
rho rho guaB guaB purN purN AIM37777.1 AIM37777.1 AIM37762.1 AIM37762.1 coaE coaE cmk cmk pyrE pyrE AIM37690.1 AIM37690.1 AIM37643.1 AIM37643.1 AIM37618.1 AIM37618.1 AIM37604.1 AIM37604.1 AIM37567.1 AIM37567.1 AIM37566.1 AIM37566.1 AIM37565.1 AIM37565.1 dinB-2 dinB-2 AIM37544.1 AIM37544.1 accA accA AIM37493.1 AIM37493.1 pyrD pyrD AIM37447.1 AIM37447.1 AIM37424.1 AIM37424.1 AIM37412.1 AIM37412.1 purA purA coaD coaD AIM37302.1 AIM37302.1 AIM37287.1 AIM37287.1 AIM37142.1 AIM37142.1 AIM37138.1 AIM37138.1 AIM37129.1 AIM37129.1 AIM37098.1 AIM37098.1 AIM37090.1 AIM37090.1 AIM37067.1 AIM37067.1 AIM37064.1 AIM37064.1 AIM37049.1 AIM37049.1 AIM36951.1 AIM36951.1 AIM36839.1 AIM36839.1 AIM36831.1 AIM36831.1 AIM36808.1 AIM36808.1 AIM36797.1 AIM36797.1 kdsB kdsB AIM36784.1 AIM36784.1 coaA coaA AIM36768.1 AIM36768.1 AIM36759.1 AIM36759.1 nusA nusA AIM36683.1 AIM36683.1 AIM36671.1 AIM36671.1 guaA guaA AIM36633.1 AIM36633.1 dinB dinB AIM36621.1 AIM36621.1 AIM36617.1 AIM36617.1 AIM36610.1 AIM36610.1 carA carA adk adk murA murA AIM36566.1 AIM36566.1 purH purH apt apt AIM36527.1 AIM36527.1 AIM36507.1 AIM36507.1 queE queE folD folD queA queA AIM36459.1 AIM36459.1 AIM36432.1 AIM36432.1 AIM36299.1 AIM36299.1 ppnK ppnK AIM36231.1 AIM36231.1 AIM37811.1 AIM37811.1 tdk tdk AIM36181.1 AIM36181.1 AIM36168.1 AIM36168.1 AIM36146.1 AIM36146.1 dnaX dnaX pncB pncB thyA thyA AIM36013.1 AIM36013.1 AIM35988.1 AIM35988.1 AIM35253.1 AIM35253.1 rpoC rpoC rpoB rpoB nusG nusG queH queH AIM35937.1 AIM35937.1 pyrH pyrH purE purE purK purK AIM35914.1 AIM35914.1 AIM35907.1 AIM35907.1 tgt tgt accD accD purC purC AIM35761.1 AIM35761.1 AIM35753.1 AIM35753.1 AIM35750.1 AIM35750.1 rpoA rpoA AIM35629.1 AIM35629.1 pdhA pdhA AIM35606.1 AIM35606.1 ndk ndk dnaG dnaG AIM35546.1 AIM35546.1 AIM35529.1 AIM35529.1 AIM35439.1 AIM35439.1 purD purD AIM35418.1 AIM35418.1 nadD nadD gmk gmk AIM35381.1 AIM35381.1 AIM35380.1 AIM35380.1 nadA nadA AIM35371.1 AIM35371.1 AIM35366.1 AIM35366.1 AIM35354.1 AIM35354.1 AIM35352.1 AIM35352.1 AIM35331.1 AIM35331.1 AIM39318.1 AIM39318.1 AIM39317.1 AIM39317.1 polA polA AIM39234.1 AIM39234.1 AIM39213.1 AIM39213.1 AIM39183.1 AIM39183.1 AIM39182.1 AIM39182.1 AIM39178.1 AIM39178.1 AIM39177.1 AIM39177.1 AIM39152.1 AIM39152.1 AIM39130.1 AIM39130.1 AIM39119.1 AIM39119.1 AIM39118.1 AIM39118.1 AIM39077.1 AIM39077.1 AIM39034.1 AIM39034.1 AIM38988.1 AIM38988.1 fcl fcl dacA dacA AIM38867.1 AIM38867.1 AIM38839.1 AIM38839.1 AIM38793.1 AIM38793.1 AIM38792.1 AIM38792.1 AIM38775.1 AIM38775.1 atpD atpD nadE nadE AIM38726.1 AIM38726.1 AIM38717.1 AIM38717.1 AIM38687.1 AIM38687.1 AIM38644.1 AIM38644.1 pyrB pyrB priA priA atpB atpB AIM38562.1 AIM38562.1 atpF atpF atpH atpH atpA atpA atpG atpG AIM38501.1 AIM38501.1 AIM38497.1 AIM38497.1 AIM38482.1 AIM38482.1 AIM38476.1 AIM38476.1 pyrG pyrG AIM38292.1 AIM38292.1 AIM38253.1 AIM38253.1 AIM38157.1 AIM38157.1 AIM38141.1 AIM38141.1 AIM38135.1 AIM38135.1 AIM38104.1 AIM38104.1 AIM38074.1 AIM38074.1 AIM37991.1 AIM37991.1 AIM37928.1 AIM37928.1 purL purL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (496 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (190 aa)
AIM37777.1Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (636 aa)
AIM37762.1Nitrogen utilization protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (315 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (193 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (215 aa)
AIM37690.1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
AIM37643.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
AIM37618.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AIM37604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (205 aa)
AIM37567.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AIM37566.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AIM37565.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (382 aa)
AIM37544.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1016 aa)
accAacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
AIM37493.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1474 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (346 aa)
AIM37447.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
AIM37424.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (278 aa)
AIM37412.1Reverse transcriptase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (156 aa)
AIM37302.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (188 aa)
AIM37287.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (284 aa)
AIM37142.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
AIM37138.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
AIM37129.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (166 aa)
AIM37098.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa)
AIM37090.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
AIM37067.1Aspartate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AIM37064.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
AIM37049.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
AIM36951.1ECF subfamily RNA polymerase sigma-24 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
AIM36839.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
AIM36831.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa)
AIM36808.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (978 aa)
AIM36797.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
AIM36784.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
coaAPantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AIM36768.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
AIM36759.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (324 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (412 aa)
AIM36683.1RNA polymerase sigma54 factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
AIM36671.1RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (286 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (516 aa)
AIM36633.1Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (365 aa)
AIM36621.1DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (535 aa)
AIM36617.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
AIM36610.1Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (366 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (441 aa)
AIM36566.1Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
AIM36527.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
AIM36507.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (207 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa)
queAS-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (349 aa)
AIM36459.1Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
AIM36432.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (218 aa)
AIM36299.1NIPSNAP family containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa)
AIM36231.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
AIM37811.1DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AIM36181.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
AIM36168.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AIM36146.1Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (603 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (390 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (273 aa)
AIM36013.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (420 aa)
AIM35988.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
AIM35253.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1425 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1269 aa)
nusGAntitermination protein NusG; Participates in transcription elongation, termination and antitermination. (181 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (216 aa)
AIM35937.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
AIM35914.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
AIM35907.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (304 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AIM35761.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
AIM35753.1Uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
AIM35750.1NadR; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa)
AIM35629.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
AIM35606.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (664 aa)
AIM35546.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (461 aa)
AIM35529.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
AIM35439.1RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (166 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (424 aa)
AIM35418.1Nicotinamide mononucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (191 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (189 aa)
AIM35381.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
AIM35380.1DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (331 aa)
AIM35371.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (530 aa)
AIM35366.1Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AIM35354.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
AIM35352.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
AIM35331.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AIM39318.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
AIM39317.1RNA polymerase Rpb6; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (935 aa)
AIM39234.1Deoxycytidine triphosphate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
AIM39213.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (71 aa)
AIM39183.1Glycerol-3-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AIM39182.1Glycerol-3-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AIM39178.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa)
AIM39177.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (289 aa)
AIM39152.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AIM39130.1dCTP deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AIM39119.1Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AIM39118.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (779 aa)
AIM39077.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
AIM39034.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
AIM38988.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (315 aa)
dacAMembrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (264 aa)
AIM38867.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
AIM38839.1RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
AIM38793.1Ribonucleotide-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (328 aa)
AIM38792.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (701 aa)
AIM38775.1ATP synthase subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
atpDATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (500 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (546 aa)
AIM38726.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AIM38717.1acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (638 aa)
AIM38687.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
AIM38644.1Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (827 aa)
atpBATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (362 aa)
AIM38562.1ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
atpFATP F0F1 synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (166 aa)
atpHATPase; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (181 aa)
atpAATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (524 aa)
atpGATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (297 aa)
AIM38501.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
AIM38497.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (449 aa)
AIM38482.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AIM38476.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa)
AIM38292.1Reverse transcriptase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AIM38253.1RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)
AIM38157.1RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
AIM38141.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)
AIM38135.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
AIM38104.1Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AIM38074.1Reverse transcriptase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AIM37991.1Phosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AIM37928.1RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (167 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1224 aa)
Your Current Organism:
Sphingobacterium sp. ML3W
NCBI taxonomy Id: 1538644
Other names: S. sp. ML3W
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