STRINGSTRING
ADZ25361.1 ADZ25361.1 ADZ25901.1 ADZ25901.1 thyA thyA ADZ25989.1 ADZ25989.1 ADZ26912.1 ADZ26912.1 ADZ27951.1 ADZ27951.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ25361.1TIGRFAM: Dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; KEGG: nmu:Nmul_A2063 dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase. (131 aa)
ADZ25901.1FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; KEGG: nmu:Nmul_A1909 FolC bifunctional protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; Belongs to the folylpolyglutamate synthase family. (432 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
ADZ25989.1Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
ADZ26912.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa)
ADZ27951.1TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: nmu:Nmul_A0881 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (162 aa)
Your Current Organism:
Nitrosomonas sp. AL212
NCBI taxonomy Id: 153948
Other names: N. sp. AL212
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.