STRINGSTRING
ADZ25350.1 ADZ25350.1 ADZ25392.1 ADZ25392.1 hemC hemC hemL hemL ADZ25546.1 ADZ25546.1 ADZ25580.1 ADZ25580.1 ADZ25581.1 ADZ25581.1 ADZ25582.1 ADZ25582.1 ADZ25583.1 ADZ25583.1 gltX gltX hemA hemA ADZ26075.1 ADZ26075.1 ADZ26448.1 ADZ26448.1 ADZ26449.1 ADZ26449.1 ADZ26450.1 ADZ26450.1 hemH hemH ADZ26685.1 ADZ26685.1 ADZ26687.1 ADZ26687.1 ADZ26688.1 ADZ26688.1 cysN cysN cysD cysD ADZ26691.1 ADZ26691.1 cysG cysG ADZ26918.1 ADZ26918.1 ADZ26920.1 ADZ26920.1 ADZ26922.1 ADZ26922.1 ADZ26923.1 ADZ26923.1 cysA cysA ADZ27026.1 ADZ27026.1 ADZ27196.1 ADZ27196.1 hemF hemF hemE hemE ADZ27884.1 ADZ27884.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ25350.1Sulfate ABC transporter, periplasmic sulfate-binding protein; KEGG: nmu:Nmul_A0507 thiosulphate-binding protein; TIGRFAM: Thiosulphate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1. (332 aa)
ADZ25392.1Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (261 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (318 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: nmu:Nmul_A2629 glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III. (426 aa)
ADZ25546.1KEGG: tgr:Tgr7_0639 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1. (199 aa)
ADZ25580.1KEGG: gca:Galf_1982 hypothetical protein. (72 aa)
ADZ25581.1KEGG: gca:Galf_1981 nitrite and sulphite reductase 4Fe-4S region; PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like. (580 aa)
ADZ25582.1PFAM: Uncharacterised conserved protein UCP030820; KEGG: hse:Hsero_3100 hypothetical protein. (177 aa)
ADZ25583.1Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. (232 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (464 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (417 aa)
ADZ26075.1Porphobilinogen synthase; KEGG: neu:NE2457 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (334 aa)
ADZ26448.1cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (201 aa)
ADZ26449.1KEGG: neu:NE0635 hypothetical protein. (192 aa)
ADZ26450.1KEGG: net:Neut_1916 TonB-dependent vitamin B12 receptor; TIGRFAM: TonB-dependent vitamin B12 receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug. (617 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (361 aa)
ADZ26685.1PFAM: Transposase, IS4-like; KEGG: atu:Atu4436 IS5 family transposase. (326 aa)
ADZ26687.1TIGRFAM: UDP-glucose 4-epimerase; KEGG: nmu:Nmul_A0260 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (344 aa)
ADZ26688.1KEGG: nmu:Nmul_A0913 hypothetical protein. (319 aa)
cysNSulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (634 aa)
cysDTIGRFAM: Sulphate adenylyltransferase, small subunit; KEGG: pzu:PHZ_c2263 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase. (298 aa)
ADZ26691.1Hypothetical protein. (30 aa)
cysGuroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (465 aa)
ADZ26918.1PFAM: Protein of unknown function DUF2292; KEGG: mei:Msip34_2148 hypothetical protein. (65 aa)
ADZ26920.1Sulfate ABC transporter, periplasmic sulfate-binding protein; KEGG: nmu:Nmul_A0507 thiosulphate-binding protein; TIGRFAM: Thiosulphate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1. (332 aa)
ADZ26922.1Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
ADZ26923.1KEGG: nmu:Nmul_A0504 sulfate ABC transporter, permease protein CysW; TIGRFAM: Sulphate ABC transporter, permease protein CysW; Sulphate ABC transporter permease protein 2; PFAM: Binding-protein-dependent transport systems inner membrane component. (307 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (366 aa)
ADZ27026.1Phosphoadenylyl-sulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (238 aa)
ADZ27196.1KEGG: neu:NE1756 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00701; PFAM: Uncharacterised protein family UPF0093. (145 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (298 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (357 aa)
ADZ27884.1Coproporphyrinogen dehydrogenase; PFAM: HemN, C-terminal; KEGG: slt:Slit_0423 oxygen-independent coproporphyrinogen III oxidase; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (481 aa)
Your Current Organism:
Nitrosomonas sp. AL212
NCBI taxonomy Id: 153948
Other names: N. sp. AL212
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