STRINGSTRING
ADZ25361.1 ADZ25361.1 ADZ25901.1 ADZ25901.1 ADZ25931.1 ADZ25931.1 thyA thyA ADZ25989.1 ADZ25989.1 ADZ26072.1 ADZ26072.1 coaX coaX engB engB ADZ26340.1 ADZ26340.1 ADZ26660.1 ADZ26660.1 ADZ26912.1 ADZ26912.1 ADZ26917.1 ADZ26917.1 nadA nadA ADZ27951.1 ADZ27951.1 panB panB panC panC
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ25361.1TIGRFAM: Dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; KEGG: nmu:Nmul_A2063 dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase. (131 aa)
ADZ25901.1FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; KEGG: nmu:Nmul_A1909 FolC bifunctional protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; Belongs to the folylpolyglutamate synthase family. (432 aa)
ADZ25931.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (532 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
ADZ25989.1Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
ADZ26072.1TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; KEGG: meh:M301_1880 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal. (331 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
engBRibosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (198 aa)
ADZ26340.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)
ADZ26660.1PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; KEGG: vdi:Vdis_0590 2-dehydropantoate 2-reductase. (340 aa)
ADZ26912.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa)
ADZ26917.1TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; KEGG: nmu:Nmul_A1543 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; Belongs to the NadC/ModD family. (289 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (367 aa)
ADZ27951.1TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: nmu:Nmul_A0881 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (162 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (274 aa)
Your Current Organism:
Nitrosomonas sp. AL212
NCBI taxonomy Id: 153948
Other names: N. sp. AL212
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