STRINGSTRING
CSCA_0064 CSCA_0064 CSCA_0076 CSCA_0076 ilvD ilvD CSCA_0379 CSCA_0379 CSCA_0573 CSCA_0573 CSCA_0815 CSCA_0815 CSCA_1055 CSCA_1055 CSCA_1096 CSCA_1096 CSCA_1166 CSCA_1166 CSCA_1267 CSCA_1267 CSCA_1297 CSCA_1297 CSCA_1338 CSCA_1338 CSCA_1339 CSCA_1339 CSCA_1340 CSCA_1340 CSCA_1341 CSCA_1341 CSCA_1342 CSCA_1342 CSCA_1352 CSCA_1352 CSCA_1535 CSCA_1535 CSCA_1573 CSCA_1573 CSCA_1616 CSCA_1616 CSCA_1705 CSCA_1705 CSCA_1706 CSCA_1706 leuB leuB leuD leuD leuC leuC leuA leuA ilvC ilvC CSCA_1714 CSCA_1714 CSCA_1716 CSCA_1716 CSCA_1733 CSCA_1733 CSCA_1735 CSCA_1735 CSCA_1737 CSCA_1737 CSCA_1766 CSCA_1766 CSCA_1881 CSCA_1881 CSCA_1968 CSCA_1968 ilvC-2 ilvC-2 CSCA_2041 CSCA_2041 CSCA_2051 CSCA_2051 CSCA_2098 CSCA_2098 CSCA_2109 CSCA_2109 CSCA_2110 CSCA_2110 CSCA_2111 CSCA_2111 CSCA_2112 CSCA_2112 CSCA_2386 CSCA_2386 CSCA_2387 CSCA_2387 CSCA_2388 CSCA_2388 CSCA_2389 CSCA_2389 CSCA_2390 CSCA_2390 CSCA_2553 CSCA_2553 CSCA_2554 CSCA_2554 CSCA_2555 CSCA_2555 CSCA_2556 CSCA_2556 CSCA_2629 CSCA_2629 CSCA_2759 CSCA_2759 ackA ackA CSCA_2820 CSCA_2820 CSCA_3212 CSCA_3212 CSCA_3215 CSCA_3215 CSCA_3517 CSCA_3517 CSCA_3617 CSCA_3617 CSCA_3671 CSCA_3671 CSCA_3672 CSCA_3672 pckA pckA CSCA_3853 CSCA_3853 CSCA_3877 CSCA_3877 CSCA_4329 CSCA_4329 CSCA_4330 CSCA_4330 CSCA_4350 CSCA_4350 CSCA_4351 CSCA_4351 CSCA_4352 CSCA_4352 CSCA_4353 CSCA_4353 CSCA_4495 CSCA_4495 CSCA_4496 CSCA_4496 CSCA_4675 CSCA_4675 CSCA_4726 CSCA_4726 CSCA_4896 CSCA_4896 CSCA_5029 CSCA_5029 CSCA_5030 CSCA_5030 CSCA_5031 CSCA_5031 CSCA_5032 CSCA_5032 CSCA_5033 CSCA_5033 CSCA_5134 CSCA_5134 CSCA_5135 CSCA_5135 CSCA_5151 CSCA_5151 CSCA_5275 CSCA_5275 CSCA_5289 CSCA_5289
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSCA_0064(S)-2-hydroxy-acid oxidase. (340 aa)
CSCA_0076Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (873 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (552 aa)
CSCA_0379Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). (393 aa)
CSCA_0573Malic enzyme. (390 aa)
CSCA_0815Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (280 aa)
CSCA_1055Lactate/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (318 aa)
CSCA_1096Hypothetical protein. (494 aa)
CSCA_1166Aspartate racemase; Belongs to the aspartate/glutamate racemases family. (230 aa)
CSCA_1267Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa)
CSCA_1297Acylphosphatase. (90 aa)
CSCA_1338Hypothetical protein. (220 aa)
CSCA_13394Fe-4S binding domain protein. (69 aa)
CSCA_13403-methyl-2-oxobutanoate dehydrogenase (ferredoxin). (356 aa)
CSCA_1341Thiamine pyrophosphate enzyme. (249 aa)
CSCA_1342Pyruvate ferredoxin/flavodoxin oxidoreductase. (176 aa)
CSCA_1352Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1175 aa)
CSCA_1535Asparagine synthase (glutamine-hydrolyzing). (613 aa)
CSCA_1573Reductase flavoprotein subunit. (485 aa)
CSCA_1616Ethanolamine utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (208 aa)
CSCA_1705Acetolactate synthase, small subunit. (116 aa)
CSCA_1706Acetolactate synthase, large subunit, biosynthetic type. (535 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (163 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (421 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
CSCA_1714Aminotransferase class I and II. (543 aa)
CSCA_1716Asparaginase/glutaminase. (326 aa)
CSCA_1733Succinate dehydrogenase. (598 aa)
CSCA_1735Succinate dehydrogenase and fumarate reductase iron-sulfur protein. (103 aa)
CSCA_1737Pyruvate, phosphate dikinase. (392 aa)
CSCA_1766Aspartate racemase; Belongs to the aspartate/glutamate racemases family. (228 aa)
CSCA_1881Fumarate lyase. (475 aa)
CSCA_1968Acetolactate synthase, large subunit, biosynthetic type. (553 aa)
ilvC-2Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
CSCA_2041Aminotransferase class I and II. (438 aa)
CSCA_2051Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (879 aa)
CSCA_2098Aminotransferase class I and II. (399 aa)
CSCA_2109Pyruvate synthase subunit porB. (313 aa)
CSCA_2110Pyruvate synthase subunit porA. (393 aa)
CSCA_2111Pyruvate synthase subunit porD. (102 aa)
CSCA_2112Pyruvate synthase subunit PorC. (192 aa)
CSCA_2386acetyl-CoA synthetase (ADP-forming), alpha and beta subunits. (698 aa)
CSCA_2387Oxidoreductase subunit. (179 aa)
CSCA_2388Hypothetical protein. (247 aa)
CSCA_2389Keto/oxoacid ferredoxin oxidoreductase, beta subunit. (351 aa)
CSCA_2390Oxidoreductase ferredoxin subunit. (65 aa)
CSCA_2553Thiamine pyrophosphate protein domain protein TPP-binding. (314 aa)
CSCA_2554Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (396 aa)
CSCA_2555Pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit. (97 aa)
CSCA_2556Pyruvate ferredoxin/flavodoxin oxidoreductase. (216 aa)
CSCA_2629Coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family. (517 aa)
CSCA_2759Aminotransferase class I and II. (397 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
CSCA_2820Phosphate acetyltransferase. (334 aa)
CSCA_3212Aminotransferase class IV. (275 aa)
CSCA_3215Pyruvate:ferredoxin oxidoreductase. (1167 aa)
CSCA_3517Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (877 aa)
CSCA_3617Cat1. (500 aa)
CSCA_3671Isocitrate dehydrogenase (NAD(+)). (334 aa)
CSCA_3672Pyruvate carboxyltransferase. (456 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
CSCA_3853Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). (390 aa)
CSCA_3877Branched-chain amino acid aminotransferase. (341 aa)
CSCA_4329Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit. (280 aa)
CSCA_4330Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type. (186 aa)
CSCA_43504Fe-4S binding domain protein. (69 aa)
CSCA_43513-methyl-2-oxobutanoate dehydrogenase (ferredoxin). (356 aa)
CSCA_4352Thiamine pyrophosphate enzyme. (249 aa)
CSCA_4353Pyruvate ferredoxin/flavodoxin oxidoreductase. (176 aa)
CSCA_4495Acetaldehyde dehydrogenase (acetylating). (534 aa)
CSCA_4496Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (216 aa)
CSCA_4675Formate acetyltransferase. (749 aa)
CSCA_4726FAD binding domain protein. (641 aa)
CSCA_4896Aconitate hydratase domain protein. (767 aa)
CSCA_5029Hypothetical protein. (230 aa)
CSCA_50304Fe-4S ferredoxin iron-sulfur binding domain protein. (67 aa)
CSCA_5031Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (359 aa)
CSCA_50323-methyl-2-oxobutanoate dehydrogenase (ferredoxin). (245 aa)
CSCA_5033Pyruvate ferredoxin/flavodoxin oxidoreductase. (181 aa)
CSCA_5134Formate acetyltransferase. (749 aa)
CSCA_5135Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (239 aa)
CSCA_5151Aminotransferase class I and II. (395 aa)
CSCA_5275Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (218 aa)
CSCA_5289Acetyl-CoA hydrolase. (502 aa)
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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