(18 nodes) Mixed, incl. Quinone metabolic process, and Carbapenem biosynthesis network (Sphingomonas taxi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIT05539.1	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	proB	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
	AIT07343.1	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
	AIT07376.1	Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	AIT07403.1	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
	AIT07405.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
	AIT07406.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	proA	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa)
	AIT07473.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
	nadD	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (206 aa)
	rsfS	Ribosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (134 aa)
	rlmH	50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (140 aa)
	AIT08292.1	Metalloendopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
	AIT07477.1	Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. (454 aa)
	AIT07478.1	Disulfide bond formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
	coq7	Ubiquinone biosynthesis protein UbiB; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (186 aa)
	AIT07480.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
	ubiG	3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (241 aa)

Your Current Organism:

Sphingomonas taxi

NCBI taxonomy Id: 1549858
Other names: ATCC 55669, Erwinia taxi, S. taxi, strain STJ.EPI.H7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIT05539.1	AIT07376.1	MC45_03000	MC45_14470	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.527
AIT05539.1	ubiG	MC45_03000	MC45_15445	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.	0.712
AIT07343.1	AIT07403.1	MC45_14255	MC45_14625	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.575
AIT07343.1	AIT07405.1	MC45_14255	MC45_14635	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.739
AIT07343.1	AIT07478.1	MC45_14255	MC45_15125	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	Disulfide bond formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.638
AIT07343.1	coq7	MC45_14255	MC45_15130	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis protein UbiB; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.	0.940
AIT07376.1	AIT05539.1	MC45_14470	MC45_03000	Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.527
AIT07376.1	coq7	MC45_14470	MC45_15130	Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis protein UbiB; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.	0.614
AIT07376.1	ubiG	MC45_14470	MC45_15445	Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.	0.972
AIT07403.1	AIT07343.1	MC45_14625	MC45_14255	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.575
AIT07403.1	AIT07405.1	MC45_14625	MC45_14635	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.954
AIT07403.1	AIT07406.1	MC45_14625	MC45_14640	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.738
AIT07405.1	AIT07343.1	MC45_14635	MC45_14255	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.739
AIT07405.1	AIT07403.1	MC45_14635	MC45_14625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.954
AIT07405.1	AIT07406.1	MC45_14635	MC45_14640	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.738
AIT07405.1	coq7	MC45_14635	MC45_15130	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis protein UbiB; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.	0.504
AIT07406.1	AIT07403.1	MC45_14640	MC45_14625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secreted (periplasmic)-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.738
AIT07406.1	AIT07405.1	MC45_14640	MC45_14635	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.738
AIT07473.1	AIT07477.1	MC45_15095	MC45_15120	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family.	0.408
AIT07473.1	AIT07478.1	MC45_15095	MC45_15125	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Disulfide bond formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.412