STRINGSTRING
AIT06162.1 AIT06162.1 AIT06171.1 AIT06171.1 AIT06185.1 AIT06185.1 AIT08065.1 AIT08065.1 proB proB AIT06277.1 AIT06277.1 sufC sufC AIT06291.1 AIT06291.1 bioD bioD argG argG AIT06330.1 AIT06330.1 AIT06335.1 AIT06335.1 AIT08092.1 AIT08092.1 AIT06377.1 AIT06377.1 ileS ileS AIT06392.1 AIT06392.1 lon lon clpX clpX gatB gatB gatA gatA gatC gatC AIT06419.1 AIT06419.1 miaA miaA AIT06451.1 AIT06451.1 AIT06454.1 AIT06454.1 groEL groEL groS groS ychF ychF queC queC argS argS ftsA ftsA murC murC murD murD murF murF murE murE AIT06533.1 AIT06533.1 AIT08138.1 AIT08138.1 metK metK AIT06573.1 AIT06573.1 AIT06577.1 AIT06577.1 hisG hisG thiL thiL AIT06604.1 AIT06604.1 tmk tmk AIT06626.1 AIT06626.1 mfd-2 mfd-2 AIT08152.1 AIT08152.1 parE parE dnaJ dnaJ dnaK dnaK grpE grpE gshB gshB priA priA atpD atpD atpG atpG atpA atpA AIT06699.1 AIT06699.1 AIT06752.1 AIT06752.1 glyS glyS glyQ glyQ gmk gmk hisE hisE AIT06785.1 AIT06785.1 mutS mutS thrS thrS AIT06801.1 AIT06801.1 AIT06810.1 AIT06810.1 AIT06830.1 AIT06830.1 AIT06835.1 AIT06835.1 AIT06851.1 AIT06851.1 tdk tdk AIT06878.1 AIT06878.1 AIT06902.1 AIT06902.1 AIT06903.1 AIT06903.1 AIT06910.1 AIT06910.1 parC parC purC purC purS purS purQ purQ guaA guaA adk adk AIT08193.1 AIT08193.1 AIT06978.1 AIT06978.1 pstB pstB argB argB AIT07010.1 AIT07010.1 uvrB uvrB AIT07021.1 AIT07021.1 AIT07033.1 AIT07033.1 AIT08204.1 AIT08204.1 AIT07044.1 AIT07044.1 uvrA uvrA xylB xylB AIT07097.1 AIT07097.1 nrdR nrdR AIT07151.1 AIT07151.1 AIT07165.1 AIT07165.1 AIT07167.1 AIT07167.1 fliI fliI AIT07197.1 AIT07197.1 AIT07208.1 AIT07208.1 AIT08251.1 AIT08251.1 lysK lysK sucC sucC prs prs gltX-2 gltX-2 AIT07240.1 AIT07240.1 AIT08254.1 AIT08254.1 ruvA ruvA ruvB ruvB AIT07269.1 AIT07269.1 tilS tilS ftsH ftsH AIT07292.1 AIT07292.1 AIT07294.1 AIT07294.1 purK purK clpB clpB AIT07311.1 AIT07311.1 purD purD AIT07331.1 AIT07331.1 AIT07339.1 AIT07339.1 AIT07340.1 AIT07340.1 AIT07358.1 AIT07358.1 AIT07362.1 AIT07362.1 AIT07377.1 AIT07377.1 coaE coaE AIT07388.1 AIT07388.1 rho rho AIT07399.1 AIT07399.1 leuS leuS AIT07418.1 AIT07418.1 ftsE ftsE AIT07422.1 AIT07422.1 nadD nadD smc smc AIT07509.1 AIT07509.1 AIT07513.1 AIT07513.1 AIT07536.1 AIT07536.1 hisS hisS AIT07576.1 AIT07576.1 cbiA cbiA cobN cobN coaD coaD clpA clpA AIT07674.1 AIT07674.1 AIT07675.1 AIT07675.1 AIT08316.1 AIT08316.1 mnmA mnmA AIT07688.1 AIT07688.1 AIT07739.1 AIT07739.1 AIT07745.1 AIT07745.1 AIT07751.1 AIT07751.1 AIT07752.1 AIT07752.1 kdpB kdpB kdpC kdpC AIT08346.1 AIT08346.1 AIT07778.1 AIT07778.1 AIT07781.1 AIT07781.1 AIT07786.1 AIT07786.1 AIT07788.1 AIT07788.1 AIT08351.1 AIT08351.1 panC panC gyrB gyrB recF recF pheS pheS pheT pheT AIT07863.1 AIT07863.1 ackA ackA AIT07870.1 AIT07870.1 AIT07881.1 AIT07881.1 ppnK ppnK mfd mfd AIT05166.1 AIT05166.1 tyrS tyrS serS serS ispE ispE recA recA alaS alaS gyrA gyrA AIT05265.1 AIT05265.1 AIT05322.1 AIT05322.1 radA radA dnaA dnaA trpS trpS AIT07923.1 AIT07923.1 AIT07931.1 AIT07931.1 glpK glpK aroK aroK accA accA valS valS AIT05431.1 AIT05431.1 cysC cysC cysD cysD AIT05460.1 AIT05460.1 AIT07944.1 AIT07944.1 AIT05493.1 AIT05493.1 nnrE nnrE AIT05520.1 AIT05520.1 AIT05521.1 AIT05521.1 pckA pckA AIT05527.1 AIT05527.1 ndk ndk AIT05544.1 AIT05544.1 ntrC ntrC AIT05546.1 AIT05546.1 metG metG acsA acsA AIT05574.1 AIT05574.1 AIT05586.1 AIT05586.1 aspS aspS ppk ppk AIT05599.1 AIT05599.1 purM purM glgC glgC AIT05626.1 AIT05626.1 accD accD AIT05645.1 AIT05645.1 AIT05652.1 AIT05652.1 AIT05664.1 AIT05664.1 AIT07971.1 AIT07971.1 AIT05670.1 AIT05670.1 AIT07978.1 AIT07978.1 AIT05702.1 AIT05702.1 pyrH pyrH lolD lolD pyrG pyrG glk glk mutL mutL AIT05772.1 AIT05772.1 acsA-2 acsA-2 AIT05801.1 AIT05801.1 mdcB mdcB secA secA AIT05818.1 AIT05818.1 AIT07995.1 AIT07995.1 AIT05834.1 AIT05834.1 anmK anmK AIT05840.1 AIT05840.1 gltX gltX AIT05859.1 AIT05859.1 coaX coaX AIT05877.1 AIT05877.1 pgk pgk AIT05893.1 AIT05893.1 AIT08008.1 AIT08008.1 cysS cysS proS proS thrB thrB AIT05972.1 AIT05972.1 AIT05982.1 AIT05982.1 glnA glnA AIT06002.1 AIT06002.1 AIT06011.1 AIT06011.1 AIT06030.1 AIT06030.1 AIT06051.1 AIT06051.1 carB carB carA carA AIT08046.1 AIT08046.1 AIT08048.1 AIT08048.1 AIT08053.1 AIT08053.1 dnaX dnaX purL purL nadE nadE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIT06162.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
AIT06171.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
AIT06185.1Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
AIT08065.1Peptidase C39; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
AIT06277.1FeS assembly SUF system protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
sufCCysteine desulfurase; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AIT06291.1PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (205 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
AIT06330.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
AIT06335.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AIT08092.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (777 aa)
AIT06377.1Chromosome partitioning protein ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (317 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (928 aa)
AIT06392.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (308 aa)
lonDNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (797 aa)
clpXClp protease ATP-binding protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)
gatBglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (489 aa)
gatAglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (498 aa)
gatCglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (100 aa)
AIT06419.1Plasmid partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (311 aa)
AIT06451.1Elongation factor 3; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
AIT06454.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
groELMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (547 aa)
groSMolecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (95 aa)
ychFGTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (231 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (420 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (472 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (431 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (454 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (471 aa)
AIT06533.1Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AIT08138.1DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (470 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (405 aa)
AIT06573.1Cobalamin biosynthesis protein CobS; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AIT06577.1Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
hisGATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (212 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (299 aa)
AIT06604.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (811 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)
AIT06626.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
mfd-2DEAD/DEAH box helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1047 aa)
AIT08152.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (660 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (373 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (633 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (184 aa)
gshBGlutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (318 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (723 aa)
atpDATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (493 aa)
atpGATP synthase F0F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
atpAATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (509 aa)
AIT06699.1Flagellar protein FlaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AIT06752.1Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (885 aa)
glySglycyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (721 aa)
glyQglycyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (218 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
AIT06785.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (859 aa)
thrSthreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (663 aa)
AIT06801.1UDP-N-acetylmuramate--alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
AIT06810.1ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (430 aa)
AIT06830.1Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AIT06835.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AIT06851.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
tdkThymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
AIT06878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AIT06902.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
AIT06903.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
AIT06910.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (750 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (259 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (76 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (222 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (518 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
AIT08193.1Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
AIT06978.1Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (252 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
AIT07010.1Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (732 aa)
AIT07021.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (648 aa)
AIT07033.1Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (889 aa)
AIT08204.1Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
AIT07044.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (487 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (966 aa)
xylBXylulose kinase; Catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AIT07097.17, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
nrdRNrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (158 aa)
AIT07151.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
AIT07165.1Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (295 aa)
AIT07167.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
fliIATP synthase; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
AIT07197.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (763 aa)
AIT07208.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
AIT08251.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (905 aa)
lysKlysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (526 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
gltX-2glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (442 aa)
AIT07240.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AIT08254.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (198 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa)
AIT07269.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (484 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (343 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (657 aa)
AIT07292.1glutamyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (290 aa)
AIT07294.1cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (182 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (351 aa)
clpBATPase AAA; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (859 aa)
AIT07311.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (419 aa)
AIT07331.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)
AIT07339.1Metal ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
AIT07340.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
AIT07358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (984 aa)
AIT07362.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AIT07377.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (185 aa)
AIT07388.1Phosphate kinase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (272 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (418 aa)
AIT07399.1Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
leuSleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (833 aa)
AIT07418.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
ftsECell division protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (236 aa)
AIT07422.1Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (206 aa)
smcChromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1128 aa)
AIT07509.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
AIT07513.1Cytochrome C biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. (184 aa)
AIT07536.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (420 aa)
hisShistidyl-tRNA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AIT07576.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (439 aa)
cobNCobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (1084 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa)
clpAClp protease ClpX; ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (771 aa)
AIT07674.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (824 aa)
AIT07675.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (821 aa)
AIT08316.1Excinuclease ABC subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
mnmAThiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (371 aa)
AIT07688.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
AIT07739.1alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AIT07745.1Rod shape-determining protein MreB; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AIT07751.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
AIT07752.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (678 aa)
kdpCATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (188 aa)
AIT08346.1Cobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (173 aa)
AIT07778.1Cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
AIT07781.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AIT07786.1Circadian clock protein KaiC; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
AIT07788.1Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AIT08351.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (841 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (351 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (368 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (787 aa)
AIT07863.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (659 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (353 aa)
AIT07870.1Nitrogen fixation protein FixL; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
AIT07881.1Arginine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (258 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1160 aa)
AIT05166.1ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (409 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (277 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (886 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (938 aa)
AIT05265.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AIT05322.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (456 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (472 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa)
AIT07923.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AIT07931.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (496 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (163 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (896 aa)
AIT05431.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
cysCAdenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (637 aa)
cysDSulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AIT05460.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (369 aa)
AIT07944.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AIT05493.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
nnrECarbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (462 aa)
AIT05520.1Nucleotide-binding protein; Displays ATPase and GTPase activities. (302 aa)
AIT05521.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa)
AIT05527.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (245 aa)
ndkPhosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
AIT05544.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
ntrCChemotaxis protein CheY; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (471 aa)
AIT05546.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (516 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
AIT05574.1DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA. (552 aa)
AIT05586.1Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (457 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (610 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (721 aa)
AIT05599.1Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (420 aa)
AIT05626.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
AIT05645.1Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (437 aa)
AIT05652.1DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
AIT05664.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)
AIT07971.1Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AIT05670.1Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
AIT07978.1General secretion pathway protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
AIT05702.1Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (243 aa)
lolDABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. (223 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (614 aa)
AIT05772.1Rod shape-determining protein MreB; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
acsA-2acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (635 aa)
AIT05801.1Malonate decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
mdcBtriphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family. (277 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (915 aa)
AIT05818.1DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1140 aa)
AIT07995.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
AIT05834.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (355 aa)
AIT05840.1Cell division protein ZipA; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (468 aa)
AIT05859.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (766 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa)
AIT05877.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (402 aa)
AIT05893.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (178 aa)
AIT08008.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (509 aa)
thrBSerine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (317 aa)
AIT05972.1Pilus assembly protein CpaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
AIT05982.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AIT06002.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AIT06011.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (579 aa)
AIT06030.1Phytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
AIT06051.1Ubiquinol-cytochrome C reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1107 aa)
carACarbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (393 aa)
AIT08046.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AIT08048.1Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AIT08053.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (548 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (739 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (681 aa)
Your Current Organism:
Sphingomonas taxi
NCBI taxonomy Id: 1549858
Other names: ATCC 55669, Erwinia taxi, S. taxi, strain STJ.EPI.H7
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