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AIT06163.1 AIT06163.1 AIT06179.1 AIT06179.1 AIT06207.1 AIT06207.1 AIT06213.1 AIT06213.1 AIT06216.1 AIT06216.1 AIT06224.1 AIT06224.1 AIT06227.1 AIT06227.1 AIT06270.1 AIT06270.1 AIT06301.1 AIT06301.1 AIT08085.1 AIT08085.1 AIT06365.1 AIT06365.1 AIT06366.1 AIT06366.1 AIT06378.1 AIT06378.1 AIT06381.1 AIT06381.1 ilvC ilvC AIT06431.1 AIT06431.1 AIT06472.1 AIT06472.1 AIT08140.1 AIT08140.1 AIT06716.1 AIT06716.1 AIT06722.1 AIT06722.1 AIT08168.1 AIT08168.1 AIT06791.1 AIT06791.1 AIT06792.1 AIT06792.1 AIT06818.1 AIT06818.1 dapB dapB AIT06855.1 AIT06855.1 AIT06989.1 AIT06989.1 AIT07035.1 AIT07035.1 AIT07075.1 AIT07075.1 AIT07113.1 AIT07113.1 AIT07142.1 AIT07142.1 AIT07149.1 AIT07149.1 AIT07152.1 AIT07152.1 AIT08243.1 AIT08243.1 folD folD AIT07282.1 AIT07282.1 AIT08261.1 AIT08261.1 gpsA gpsA AIT07350.1 AIT07350.1 aroE aroE AIT07442.1 AIT07442.1 AIT07463.1 AIT07463.1 AIT07495.1 AIT07495.1 AIT07510.1 AIT07510.1 AIT07572.1 AIT07572.1 AIT07595.1 AIT07595.1 AIT07621.1 AIT07621.1 AIT08314.1 AIT08314.1 AIT07708.1 AIT07708.1 AIT07717.1 AIT07717.1 AIT07735.1 AIT07735.1 AIT07753.1 AIT07753.1 AIT07756.1 AIT07756.1 AIT07757.1 AIT07757.1 AIT07831.1 AIT07831.1 AIT07826.1 AIT07826.1 AIT05116.1 AIT05116.1 AIT05121.1 AIT05121.1 AIT05146.1 AIT05146.1 AIT05177.1 AIT05177.1 AIT05191.1 AIT05191.1 AIT05203.1 AIT05203.1 AIT05218.1 AIT05218.1 AIT07895.1 AIT07895.1 AIT05236.1 AIT05236.1 AIT05247.1 AIT05247.1 AIT05251.1 AIT05251.1 AIT05280.1 AIT05280.1 AIT05290.1 AIT05290.1 AIT05291.1 AIT05291.1 AIT05299.1 AIT05299.1 AIT05309.1 AIT05309.1 AIT07918.1 AIT07918.1 AIT05333.1 AIT05333.1 AIT05339.1 AIT05339.1 proC proC AIT05389.1 AIT05389.1 AIT05400.1 AIT05400.1 AIT05446.1 AIT05446.1 AIT05505.1 AIT05505.1 AIT05575.1 AIT05575.1 AIT05605.1 AIT05605.1 AIT05606.1 AIT05606.1 sucD sucD mdh mdh AIT05630.1 AIT05630.1 AIT07975.1 AIT07975.1 AIT05691.1 AIT05691.1 AIT05707.1 AIT05707.1 dxr dxr argC argC zwf zwf AIT05764.1 AIT05764.1 ahcY ahcY asd asd gapA gapA AIT05898.1 AIT05898.1 AIT05902.1 AIT05902.1 AIT05904.1 AIT05904.1 AIT05921.1 AIT05921.1 AIT05939.1 AIT05939.1 AIT05944.1 AIT05944.1 AIT08019.1 AIT08019.1 AIT05989.1 AIT05989.1 AIT06023.1 AIT06023.1 AIT06050.1 AIT06050.1 AIT08054.1 AIT08054.1 AIT06112.1 AIT06112.1 AIT06129.1 AIT06129.1 AIT06138.1 AIT06138.1 AIT08058.1 AIT08058.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIT06163.1Saccharopine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
AIT06179.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
AIT06207.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AIT06213.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AIT06216.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AIT06224.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AIT06227.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AIT06270.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
AIT06301.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (298 aa)
AIT08085.1Galactose 1-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AIT06365.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (279 aa)
AIT06366.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AIT06378.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AIT06381.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AIT06431.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AIT06472.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1534 aa)
AIT08140.1Malonic semialdehyde reductase; NADP(+)-dependent; catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde, catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
AIT06716.1enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
AIT06722.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa)
AIT08168.1NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AIT06791.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AIT06792.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (752 aa)
AIT06818.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (242 aa)
AIT06855.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AIT06989.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
AIT07035.1Sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AIT07075.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (332 aa)
AIT07113.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (290 aa)
AIT07142.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
AIT07149.1NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
AIT07152.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AIT08243.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
AIT07282.1acetoacetyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AIT08261.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (325 aa)
AIT07350.1Cyclohexadienyl dehydrogenase; Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (264 aa)
AIT07442.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AIT07463.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AIT07495.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
AIT07510.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (262 aa)
AIT07572.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
AIT07595.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AIT07621.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AIT08314.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AIT07708.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
AIT07717.1F420-dependent NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AIT07735.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
AIT07753.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AIT07756.1NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AIT07757.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
AIT07831.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
AIT07826.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AIT05116.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AIT05121.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
AIT05146.1Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (273 aa)
AIT05177.1Protein CapI; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
AIT05191.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (772 aa)
AIT05203.1Sodium:proton exchanger; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (596 aa)
AIT05218.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AIT07895.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AIT05236.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AIT05247.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AIT05251.1DltE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
AIT05280.1Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (611 aa)
AIT05290.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
AIT05291.1NmrA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AIT05299.1Ketoacyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AIT05309.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (295 aa)
AIT07918.1Sodium:proton exchanger; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (588 aa)
AIT05333.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AIT05339.1UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (433 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
AIT05389.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AIT05400.1Glucose-fructose oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
AIT05446.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AIT05505.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AIT05575.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AIT05605.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AIT05606.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
sucDsuccinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AIT05630.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (335 aa)
AIT07975.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (368 aa)
AIT05691.1Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (350 aa)
AIT05707.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa)
AIT05764.13-oxoacyl-ACP synthase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (473 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
AIT05898.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (670 aa)
AIT05902.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AIT05904.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AIT05921.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
AIT05939.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AIT05944.1Glucose-fructose oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
AIT08019.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
AIT05989.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
AIT06023.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (281 aa)
AIT06050.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AIT08054.1Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AIT06112.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
AIT06129.1Inositol-3-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
AIT06138.13-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AIT08058.1NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
Your Current Organism:
Sphingomonas taxi
NCBI taxonomy Id: 1549858
Other names: ATCC 55669, Erwinia taxi, S. taxi, strain STJ.EPI.H7
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