(11 nodes) Mixed, incl. Iron hydrogenase, and Biotin and Thiamin Synthesis associated domain network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC39000.1	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
	APC39464.1	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
	APC39465.1	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
	APC39702.1	2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
	APC39733.1	NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
	APC39734.1	NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
	APC42603.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
	APC40498.1	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	APC40594.1	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
	APC40858.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
	APC42404.1	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC39000.1	APC39464.1	A7L45_02425	A7L45_04985	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
APC39000.1	APC39465.1	A7L45_02425	A7L45_04990	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
APC39000.1	APC39734.1	A7L45_02425	A7L45_06455	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.649
APC39000.1	APC40498.1	A7L45_02425	A7L45_10680	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.968
APC39000.1	APC40594.1	A7L45_02425	A7L45_11195	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.552
APC39000.1	APC42404.1	A7L45_02425	A7L45_21360	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.746
APC39000.1	APC42603.1	A7L45_02425	A7L45_06460	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817
APC39464.1	APC39000.1	A7L45_04985	A7L45_02425	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
APC39464.1	APC39465.1	A7L45_04985	A7L45_04990	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
APC39464.1	APC40498.1	A7L45_04985	A7L45_10680	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
APC39464.1	APC42404.1	A7L45_04985	A7L45_21360	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
APC39464.1	APC42603.1	A7L45_04985	A7L45_06460	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
APC39465.1	APC39000.1	A7L45_04990	A7L45_02425	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
APC39465.1	APC39464.1	A7L45_04990	A7L45_04985	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron-only hydrogenase system regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
APC39465.1	APC39734.1	A7L45_04990	A7L45_06455	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
APC39465.1	APC40498.1	A7L45_04990	A7L45_10680	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.519
APC39465.1	APC40594.1	A7L45_04990	A7L45_11195	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
APC39465.1	APC42404.1	A7L45_04990	A7L45_21360	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
APC39465.1	APC42603.1	A7L45_04990	A7L45_06460	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.759
APC39702.1	APC39733.1	A7L45_06280	A7L45_06450	2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.872