(39 nodes) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain, and OmpR/PhoB-type DNA-binding domain network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC38688.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (450 aa)
	APC38721.1	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
	APC38901.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC38904.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
	APC38926.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	APC38929.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	APC39024.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
	APC39025.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC39027.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC42542.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
	APC39125.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APC39126.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
	APC42557.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	APC39682.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (485 aa)
	APC39844.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
	APC39845.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	APC39846.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC39847.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
	APC39852.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (486 aa)
	APC42624.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	APC40151.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
	APC40152.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APC40165.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
	APC40279.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (315 aa)
	APC40502.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
	APC40503.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC40601.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
	APC40602.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC42687.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	APC42686.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
	APC41700.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
	APC41702.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
	APC41714.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
	APC41879.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (688 aa)
	APC42137.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (482 aa)
	APC42804.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	APC42397.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC42425.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (487 aa)
	APC42426.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC38688.1	APC38721.1	A7L45_00685	A7L45_00855	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
APC38688.1	APC38901.1	A7L45_00685	A7L45_01865	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
APC38688.1	APC38904.1	A7L45_00685	A7L45_01880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Histidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.560
APC38688.1	APC38926.1	A7L45_00685	A7L45_02005	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
APC38688.1	APC38929.1	A7L45_00685	A7L45_02020	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.554
APC38688.1	APC39024.1	A7L45_00685	A7L45_02545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689
APC38688.1	APC39025.1	A7L45_00685	A7L45_02550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.719
APC38688.1	APC39027.1	A7L45_00685	A7L45_02560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.801
APC38688.1	APC39125.1	A7L45_00685	A7L45_03110	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
APC38688.1	APC39126.1	A7L45_00685	A7L45_03115	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.541
APC38688.1	APC39682.1	A7L45_00685	A7L45_06180	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.671
APC38688.1	APC39844.1	A7L45_00685	A7L45_07055	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.674
APC38688.1	APC39845.1	A7L45_00685	A7L45_07060	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
APC38688.1	APC39846.1	A7L45_00685	A7L45_07070	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.805
APC38688.1	APC39847.1	A7L45_00685	A7L45_07075	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.675
APC38688.1	APC39852.1	A7L45_00685	A7L45_07105	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.892
APC38688.1	APC40151.1	A7L45_00685	A7L45_08755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.657
APC38688.1	APC40152.1	A7L45_00685	A7L45_08760	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
APC38688.1	APC40165.1	A7L45_00685	A7L45_08835	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.893
APC38688.1	APC40279.1	A7L45_00685	A7L45_09475	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.645