(5 nodes) Mixed, incl. D-glucosamine PTS permease activity, and Short-chain dehydrogenase/reductase, conserved site network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC38834.1	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (272 aa)
	APC42532.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
	srlA	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
	APC38838.1	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
	APC38839.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC38834.1	APC38838.1	A7L45_01505	A7L45_01530	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
APC38834.1	APC38839.1	A7L45_01505	A7L45_01535	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
APC38834.1	APC42532.1	A7L45_01505	A7L45_01515	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.965
APC38834.1	srlA	A7L45_01505	A7L45_01525	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
APC38838.1	APC38834.1	A7L45_01530	A7L45_01505	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.985
APC38838.1	APC38839.1	A7L45_01530	A7L45_01535	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APC38838.1	APC42532.1	A7L45_01530	A7L45_01515	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
APC38838.1	srlA	A7L45_01530	A7L45_01525	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APC38839.1	APC38834.1	A7L45_01535	A7L45_01505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.987
APC38839.1	APC38838.1	A7L45_01535	A7L45_01530	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APC38839.1	APC42532.1	A7L45_01535	A7L45_01515	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
APC38839.1	srlA	A7L45_01535	A7L45_01525	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APC42532.1	APC38834.1	A7L45_01515	A7L45_01505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.965
APC42532.1	APC38838.1	A7L45_01515	A7L45_01530	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
APC42532.1	APC38839.1	A7L45_01515	A7L45_01535	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
APC42532.1	srlA	A7L45_01515	A7L45_01525	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
srlA	APC38834.1	A7L45_01525	A7L45_01505	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.993
srlA	APC38838.1	A7L45_01525	A7L45_01530	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
srlA	APC38839.1	A7L45_01525	A7L45_01535	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
srlA	APC42532.1	A7L45_01525	A7L45_01515	PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988