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uxuA-2 uxuA-2 APC38723.1 APC38723.1 APC38967.1 APC38967.1 APC42543.1 APC42543.1 APC39043.1 APC39043.1 APC39572.1 APC39572.1 APC39573.1 APC39573.1 pduC pduC pduD pduD pduE pduE ilvD ilvD APC39777.1 APC39777.1 uxuA uxuA APC39883.1 APC39883.1 hutU hutU APC40179.1 APC40179.1 iolE iolE hisB hisB trpA trpA trpB trpB dapA dapA A7L45_18645 A7L45_18645 APC42010.1 APC42010.1 fabZ fabZ APC42228.1 APC42228.1 eno eno aroD aroD APC40789.1 APC40789.1 nnrE nnrE leuC leuC leuD leuD APC41610.1 APC41610.1 APC42011.1 APC42011.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uxuA-2Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (355 aa)
APC38723.1Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
APC38967.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
APC42543.1Oleate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
APC39043.12-hydroxyglutaryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
APC39572.16-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
APC39573.12-hydroxyglutaryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
pduCPropanediol dehydratase; With pduED catalyzes the formation of propionaldehyde from 1,2-propanediol; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
pduDPropanediol dehydratase; With PduCE catalyzes the formation of propionaldehyde from 1,2-propanediol; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
pduEPropanediol dehydratase; With pduCD catalyzes the formation of propionaldehyde from 1,2-propanediol; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (556 aa)
APC39777.1Altronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (355 aa)
APC39883.1Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (572 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (675 aa)
APC40179.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
iolEMyo-inosose-2 dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). (298 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (391 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa)
A7L45_18645Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (351 aa)
APC42010.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (321 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa)
APC42228.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (352 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (254 aa)
APC40789.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
nnrEBifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...] (500 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (163 aa)
APC41610.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
APC42011.1uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
Your Current Organism:
Clostridium estertheticum
NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum
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