(17 nodes) Intramolecular oxidoreductase activity, interconverting aldoses and ketoses network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC40739.1	Fucose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
	nagB	Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (241 aa)
	tpiA	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
	APC38774.1	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
	pgi	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (450 aa)
	APC38966.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	APC39156.1	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
	trpF	N-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (230 aa)
	rhaA	L-rhamnose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the rhamnose isomerase family. (418 aa)
	araA	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (488 aa)
	APC42591.1	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
	uxaC	Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
	kduI	5-dehydro-4-deoxy-D-glucuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (276 aa)
	APC40208.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
	APC40215.1	5-deoxyglucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	hisA	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	trpF-2	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (198 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC38774.1	APC39156.1	A7L45_01140	A7L45_03285	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
APC38774.1	araA	A7L45_01140	A7L45_04895	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	0.468
APC38774.1	pgi	A7L45_01140	A7L45_01545	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	0.582
APC38774.1	tpiA	A7L45_01140	A7L45_19490	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.651
APC38774.1	uxaC	A7L45_01140	A7L45_06660	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.425
APC39156.1	APC38774.1	A7L45_03285	A7L45_01140	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
APC42591.1	nagB	A7L45_05400	A7L45_17960	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.921
APC42591.1	pgi	A7L45_05400	A7L45_01545	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	0.952
APC42591.1	tpiA	A7L45_05400	A7L45_19490	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.495
araA	APC38774.1	A7L45_04895	A7L45_01140	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
araA	pgi	A7L45_04895	A7L45_01545	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	0.417
araA	rhaA	A7L45_04895	A7L45_04770	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	L-rhamnose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the rhamnose isomerase family.	0.439
araA	tpiA	A7L45_04895	A7L45_19490	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.416
kduI	uxaC	A7L45_06720	A7L45_06660	5-dehydro-4-deoxy-D-glucuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.	Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
nagB	APC42591.1	A7L45_17960	A7L45_05400	Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
nagB	pgi	A7L45_17960	A7L45_01545	Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	0.943
pgi	APC38774.1	A7L45_01545	A7L45_01140	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.582
pgi	APC42591.1	A7L45_01545	A7L45_05400	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
pgi	araA	A7L45_01545	A7L45_04895	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.	0.417
pgi	nagB	A7L45_01545	A7L45_17960	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.	Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.943