(73 nodes) Histidine kinase-like ATPases network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC41700.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
	APC38688.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (450 aa)
	APC38721.1	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
	APC38904.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
	APC38929.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	APC38935.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
	APC38941.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
	APC38946.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
	APC39024.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
	APC42542.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
	APC39085.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
	APC39095.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
	APC39101.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	APC42552.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
	APC39126.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
	APC42555.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	APC39154.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
	APC42557.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	APC39184.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
	APC39225.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
	APC39238.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	APC39339.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (604 aa)
	APC39407.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
	APC39428.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	APC39510.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (589 aa)
	APC39580.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
	APC39669.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	APC39682.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (485 aa)
	APC39822.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	APC39844.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
	APC39847.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
	APC39852.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (486 aa)
	APC39859.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
	APC39866.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
	APC39908.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
	APC39936.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (457 aa)
	APC39944.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
	APC42624.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	APC42628.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	APC40088.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	APC40109.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
	APC42638.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (605 aa)
	APC40151.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
	APC40165.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
	APC42651.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
	APC40261.1	Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
	APC40279.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (315 aa)
	htpG	Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (626 aa)
	APC40502.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
	APC40533.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
	APC42667.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	APC40601.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
	APC40649.1	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
	spoIIAB	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (142 aa)
	APC42687.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	APC40874.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	mutL	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (658 aa)
	APC41187.1	Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (680 aa)
	APC41503.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
	APC41509.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
	APC41586.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
	APC41636.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
	APC41645.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
	APC41693.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
	APC41716.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (215 aa)
	APC41757.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
	APC41879.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (688 aa)
	APC41894.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	APC42137.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (482 aa)
	APC42203.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (652 aa)
	APC42804.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	APC42425.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (487 aa)
	APC42448.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC38688.1	APC38721.1	A7L45_00685	A7L45_00855	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
APC38688.1	APC38904.1	A7L45_00685	A7L45_01880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Histidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.560
APC38688.1	APC38929.1	A7L45_00685	A7L45_02020	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.554
APC38688.1	APC38935.1	A7L45_00685	A7L45_02060	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666
APC38688.1	APC38941.1	A7L45_00685	A7L45_02095	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.660
APC38688.1	APC38946.1	A7L45_00685	A7L45_02130	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.581
APC38688.1	APC39024.1	A7L45_00685	A7L45_02545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689
APC38688.1	APC39085.1	A7L45_00685	A7L45_02885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.455
APC38688.1	APC39095.1	A7L45_00685	A7L45_02935	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.528
APC38688.1	APC39101.1	A7L45_00685	A7L45_02970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666
APC38688.1	APC39126.1	A7L45_00685	A7L45_03115	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.541
APC38688.1	APC39184.1	A7L45_00685	A7L45_03465	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.638
APC38688.1	APC39225.1	A7L45_00685	A7L45_03685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
APC38688.1	APC39238.1	A7L45_00685	A7L45_03750	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.668
APC38688.1	APC39669.1	A7L45_00685	A7L45_06105	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.667
APC38688.1	APC39682.1	A7L45_00685	A7L45_06180	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.671
APC38688.1	APC39822.1	A7L45_00685	A7L45_06940	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
APC38688.1	APC39844.1	A7L45_00685	A7L45_07055	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.674
APC38688.1	APC39847.1	A7L45_00685	A7L45_07075	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.675
APC38688.1	APC39852.1	A7L45_00685	A7L45_07105	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.892