(68 nodes) cheY-homologous receiver domain network (Clostridium estertheticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC40503.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC40566.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
	APC40602.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC40650.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	APC42686.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
	APC40873.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
	APC41003.1	Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (272 aa)
	APC41185.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	cheB-2	Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (356 aa)
	APC41504.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	APC41510.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	APC41592.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
	APC41637.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	APC41644.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	APC41692.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (533 aa)
	APC41702.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
	APC41714.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
	APC41715.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	APC41758.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
	APC41895.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	APC41899.1	Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (271 aa)
	APC42397.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC42426.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
	APC42447.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	APC40190.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
	APC40152.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APC40143.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (536 aa)
	APC40142.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (523 aa)
	APC40108.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APC40089.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APC40073.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC39943.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	APC39935.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	APC39907.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	APC39865.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	APC39858.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APC39846.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC39845.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	APC39823.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC39670.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APC39579.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
	APC39555.1	Chemotaxis protein CheV; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
	APC39511.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
	APC39427.1	Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (272 aa)
	APC39408.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	APC39340.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (510 aa)
	APC39237.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC39224.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	APC39185.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	APC39155.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
	APC39139.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	APC39125.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APC39122.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
	APC42549.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	APC39094.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	APC39086.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APC39027.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC39025.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APC38945.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APC38940.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	APC38934.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC38926.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	APC38901.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APC40259.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
	APC40260.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
	cheB	Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (345 aa)
	APC42658.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
	APC40532.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)

Your Current Organism:

Clostridium estertheticum

NCBI taxonomy Id: 1552
Other names: C. estertheticum subsp. estertheticum, Clostridium estertheticum subsp. estertheticum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC38901.1	APC41185.1	A7L45_01865	A7L45_14435	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.441
APC38926.1	APC41185.1	A7L45_02005	A7L45_14435	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
APC38926.1	APC41592.1	A7L45_02005	A7L45_16645	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.415
APC38926.1	APC41714.1	A7L45_02005	A7L45_17375	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
APC38934.1	APC41702.1	A7L45_02055	A7L45_17315	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.551
APC38934.1	APC41714.1	A7L45_02055	A7L45_17375	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.635
APC38940.1	APC41592.1	A7L45_02090	A7L45_16645	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
APC38945.1	APC41714.1	A7L45_02125	A7L45_17375	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.504
APC39025.1	APC41185.1	A7L45_02550	A7L45_14435	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.400
APC39027.1	APC40503.1	A7L45_02560	A7L45_10710	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903
APC39086.1	APC41714.1	A7L45_02890	A7L45_17375	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.536
APC39094.1	APC39185.1	A7L45_02930	A7L45_03470	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
APC39094.1	APC41592.1	A7L45_02930	A7L45_16645	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.501
APC39125.1	APC41592.1	A7L45_03110	A7L45_16645	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.485
APC39155.1	APC40259.1	A7L45_03280	A7L45_09360	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.486
APC39155.1	APC40566.1	A7L45_03280	A7L45_11035	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
APC39155.1	APC41715.1	A7L45_03280	A7L45_17380	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.536
APC39185.1	APC39094.1	A7L45_03470	A7L45_02930	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
APC39185.1	APC41714.1	A7L45_03470	A7L45_17375	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.735
APC39224.1	APC39408.1	A7L45_03680	A7L45_04695	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.497