STRINGSTRING
OJG67859.1 OJG67859.1 OJG67842.1 OJG67842.1 OJG67833.1 OJG67833.1 OJG67809.1 OJG67809.1 rbsK rbsK OJG64054.1 OJG64054.1 OJG64567.1 OJG64567.1 OJG64564.1 OJG64564.1 OJG64562.1 OJG64562.1 OJG68556.1 OJG68556.1 OJG68543.1 OJG68543.1 OJG68508.1 OJG68508.1 OJG68488.1 OJG68488.1 OJG68470.1 OJG68470.1 OJG68469.1 OJG68469.1 OJG68456.1 OJG68456.1 OJG68449.1 OJG68449.1 OJG68402.1 OJG68402.1 OJG68400.1 OJG68400.1 OJG68366.1 OJG68366.1 OJG68338.1 OJG68338.1 OJG68323.1 OJG68323.1 OJG68316.1 OJG68316.1 adk adk OJG68264.1 OJG68264.1 iolC iolC gpmA gpmA OJG68227.1 OJG68227.1 OJG68221.1 OJG68221.1 coaA coaA OJG64742.1 OJG64742.1 anmK anmK OJG64773.1 OJG64773.1 OJG64769.1 OJG64769.1 OJG64767.1 OJG64767.1 OJG64953.1 OJG64953.1 OJG64929.1 OJG64929.1 OJG65164.1 OJG65164.1 hprK hprK OJG65388.1 OJG65388.1 OJG65384.1 OJG65384.1 OJG65383.1 OJG65383.1 OJG65368.1 OJG65368.1 glpK-2 glpK-2 OJG65640.1 OJG65640.1 OJG65791.1 OJG65791.1 OJG65781.1 OJG65781.1 OJG69058.1 OJG69058.1 OJG69047.1 OJG69047.1 thrB thrB OJG69037.1 OJG69037.1 OJG69030.1 OJG69030.1 pyrH pyrH OJG69009.1 OJG69009.1 pgi pgi OJG68941.1 OJG68941.1 OJG68913.1 OJG68913.1 aroK aroK cmk cmk OJG68810.1 OJG68810.1 OJG68805.1 OJG68805.1 OJG68791.1 OJG68791.1 OJG68758.1 OJG68758.1 OJG68736.1 OJG68736.1 OJG68686.1 OJG68686.1 OJG68684.1 OJG68684.1 OJG68605.1 OJG68605.1 OJG69085.1 OJG69085.1 pfkA pfkA OJG69118.1 OJG69118.1 OJG69126.1 OJG69126.1 OJG69138.1 OJG69138.1 OJG69150.1 OJG69150.1 OJG67725.1 OJG67725.1 OJG67728.1 OJG67728.1 OJG67742.1 OJG67742.1 OJG67336.1 OJG67336.1 OJG67398.1 OJG67398.1 coaE coaE OJG67482.1 OJG67482.1 OJG67501.1 OJG67501.1 OJG67193.1 OJG67193.1 prs-2 prs-2 ackA ackA OJG67279.1 OJG67279.1 OJG67286.1 OJG67286.1 pgk pgk tpiA tpiA eno eno OJG67306.1 OJG67306.1 OJG67014.1 OJG67014.1 OJG67015.1 OJG67015.1 OJG67016.1 OJG67016.1 OJG67083.1 OJG67083.1 OJG67099.1 OJG67099.1 OJG67104.1 OJG67104.1 udk udk OJG67154.1 OJG67154.1 OJG66877.1 OJG66877.1 OJG66892.1 OJG66892.1 OJG66923.1 OJG66923.1 ldh ldh OJG66772.1 OJG66772.1 OJG66820.1 OJG66820.1 OJG66826.1 OJG66826.1 OJG69159.1 OJG69159.1 argB argB OJG69194.1 OJG69194.1 OJG69225.1 OJG69225.1 OJG69241.1 OJG69241.1 OJG69247.1 OJG69247.1 OJG69251.1 OJG69251.1 OJG69280.1 OJG69280.1 thiM thiM OJG69285.1 OJG69285.1 OJG69289.1 OJG69289.1 citG citG OJG69341.1 OJG69341.1 OJG69349.1 OJG69349.1 pdhA pdhA glpK glpK OJG66672.1 OJG66672.1 galK galK tmk tmk OJG66556.1 OJG66556.1 OJG66598.1 OJG66598.1 OJG66131.1 OJG66131.1 OJG66134.1 OJG66134.1 OJG66155.1 OJG66155.1 OJG65736.1 OJG65736.1 OJG65739.1 OJG65739.1 OJG65742.1 OJG65742.1 gmk gmk prs prs ispE ispE proB proB OJG67623.1 OJG67623.1 OJG67622.1 OJG67622.1 OJG67621.1 OJG67621.1 OJG67605.1 OJG67605.1 OJG67604.1 OJG67604.1 OJG67603.1 OJG67603.1 tdk tdk OJG68120.1 OJG68120.1 selD selD OJG68096.1 OJG68096.1 OJG68079.1 OJG68079.1 OJG68003.1 OJG68003.1 nadK nadK OJG67962.1 OJG67962.1 OJG67892.1 OJG67892.1 OJG67880.1 OJG67880.1 OJG67878.1 OJG67878.1 OJG67869.1 OJG67869.1 OJG67844.1 OJG67844.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OJG67859.1Carbamate kinase; Belongs to the carbamate kinase family. (312 aa)
OJG67842.1Sigma-54 dependent DNA-binding response regulator. (923 aa)
OJG67833.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
OJG67809.1Hypothetical protein. (106 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
OJG64054.1PTS system, beta-glucoside-specific IIABC component. (638 aa)
OJG64567.1PTS system, sucrose-specific IIBC component. (653 aa)
OJG64564.1Fructokinase. (290 aa)
OJG64562.1Hypothetical protein. (309 aa)
OJG68556.1Capsular exopolysaccharide family protein. (233 aa)
OJG68543.1Sensor histidine kinase. (366 aa)
OJG68508.1Aspartate kinase; Belongs to the aspartokinase family. (461 aa)
OJG68488.1Ketose-bisphosphate aldolase. (287 aa)
OJG68470.1Hypothetical protein. (339 aa)
OJG68469.1Hypothetical protein. (142 aa)
OJG68456.1PTS system, glucose-like IIB component. (526 aa)
OJG68449.1PTS system, glucose-like IIB component. (482 aa)
OJG68402.1Glycerate kinase; Belongs to the glycerate kinase type-1 family. (376 aa)
OJG68400.1Hypothetical protein. (884 aa)
OJG68366.1Hypothetical protein. (440 aa)
OJG68338.1PTS system, beta-glucoside-specific IIABC component. (618 aa)
OJG68323.1PTS system, beta-glucoside-specific IIABC component. (588 aa)
OJG68316.1PTS system, beta-glucoside-specific IIABC component. (626 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa)
OJG68264.1Hypothetical protein. (101 aa)
iolC5-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP). (319 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (228 aa)
OJG68227.1Fructokinase. (287 aa)
OJG68221.1Hypothetical protein. (568 aa)
coaAPantothenate kinase. (315 aa)
OJG64742.1ROK family protein. (291 aa)
anmKHypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa)
OJG64773.1PTS system, beta-glucoside-specific IIABC component. (626 aa)
OJG64769.1Hypothetical protein. (102 aa)
OJG64767.1Hypothetical protein. (887 aa)
OJG64953.1Sensor histidine kinase. (349 aa)
OJG64929.1Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (321 aa)
OJG65164.1PTS system, lactose/cellobiose family IIB component. (111 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (315 aa)
OJG65388.1PTS system, lactose/cellobiose family IIB component. (109 aa)
OJG65384.1PTS system, lactose/cellobiose family IIB component. (114 aa)
OJG65383.1Sigma-54 factor interaction domain-containing protein. (904 aa)
OJG65368.1Hypothetical protein. (189 aa)
glpK-2Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa)
OJG65640.1Sensor histidine kinase. (341 aa)
OJG65791.1Hypothetical protein. (448 aa)
OJG65781.1PTS system, beta-glucoside-specific IIABC component. (632 aa)
OJG69058.1PTS system IIBC component. (478 aa)
OJG69047.1Phosphomethylpyrimidine kinase. (274 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (257 aa)
OJG69037.1Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (285 aa)
OJG69030.1Diacylglycerol kinase. (106 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
OJG69009.1Hypothetical protein. (485 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa)
OJG68941.1PTS system, N-acetylglucosamine-specific IIBC component. (653 aa)
OJG68913.1Hypothetical protein. (416 aa)
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (166 aa)
cmkCytidylate kinase. (222 aa)
OJG68810.1Hypothetical protein. (172 aa)
OJG68805.1Hypothetical protein. (98 aa)
OJG68791.1Sensory box histidine kinase. (573 aa)
OJG68758.1Sensor histidine kinase. (489 aa)
OJG68736.1Hypothetical protein. (167 aa)
OJG68686.1Pyruvate, phosphate dikinase. (869 aa)
OJG68684.1Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
OJG68605.1Carbamate kinase; Belongs to the carbamate kinase family. (312 aa)
OJG69085.1Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
OJG69118.1Hypothetical protein. (192 aa)
OJG69126.1Ethanolamine utilization protein EutQ. (151 aa)
OJG69138.1Hypothetical protein. (468 aa)
OJG69150.1PTS system, beta-glucoside-specific IIABC component. (610 aa)
OJG67725.1Serine/threonine protein kinase. (717 aa)
OJG67728.1Thiamine pyrophosphokinase. (209 aa)
OJG67742.1Nucleoside diphosphate kinase. (133 aa)
OJG67336.1Sensor histidine kinase. (500 aa)
OJG67398.1PTS system, trehalose-specific IIBC component. (489 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
OJG67482.1Hypothetical protein. (202 aa)
OJG67501.1PTS system, beta-glucoside-specific IIABC component. (612 aa)
OJG67193.1Hypothetical protein. (476 aa)
prs-2Ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
OJG67279.1RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (737 aa)
OJG67286.1Hypothetical protein. (311 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
OJG67306.1Hypothetical protein. (498 aa)
OJG67014.1Mevalonate kinase. (314 aa)
OJG67015.1Diphosphomevalonate decarboxylase. (332 aa)
OJG67016.1Phosphomevalonate kinase. (282 aa)
OJG67083.1Carbohydrate kinase. (336 aa)
OJG67099.1Hypothetical protein. (434 aa)
OJG67104.1Hypothetical protein. (359 aa)
udkUridine kinase. (209 aa)
OJG67154.1Hypothetical protein. (179 aa)
OJG66877.1Gluconate kinase. (509 aa)
OJG66892.1Hypothetical protein. (305 aa)
OJG66923.1Hypothetical protein. (371 aa)
ldhL-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa)
OJG66772.1Carbamate kinase; Belongs to the carbamate kinase family. (305 aa)
OJG66820.1PTS system, glucose-like IIB component. (459 aa)
OJG66826.1PTS system, beta-glucoside-specific IIABC component. (641 aa)
OJG69159.1Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (315 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (250 aa)
OJG69194.1PAS domain S-box protein. (609 aa)
OJG69225.1Carbohydrate kinase, FGGY family protein. (541 aa)
OJG69241.1Fructokinase. (291 aa)
OJG69247.1Fructose-1,6-bisphosphate aldolase, class II. (288 aa)
OJG69251.1PTS system, alpha-glucoside-specific IIBC component. (534 aa)
OJG69280.1Phosphomethylpyrimidine kinase. (266 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (237 aa)
OJG69285.1YegS//BmrU family lipid kinase. (302 aa)
OJG69289.1Hypothetical protein. (508 aa)
citGtriphosphoribosyl-dephospho-CoA synthase CitG. (251 aa)
OJG69341.1Hypothetical protein. (606 aa)
OJG69349.1Hypothetical protein. (408 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)
OJG66672.1Glucokinase. (323 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (389 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
OJG66556.1PTS system, IIBC component. (725 aa)
OJG66598.1Aminoglycoside phosphotransferase. (259 aa)
OJG66131.1Hypothetical protein. (127 aa)
OJG66134.1PTS system, glucose-like IIB component. (448 aa)
OJG66155.11-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (304 aa)
OJG65736.11-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (312 aa)
OJG65739.1PTS system IIB component. (161 aa)
OJG65742.1PTS system IIA component. (134 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
prsRibose-phosphate pyrophosphokinase 1; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (283 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (264 aa)
OJG67623.1Dihydroxyacetone kinase, L subunit. (195 aa)
OJG67622.1Dihydroxyacetone kinase, DhaK subunit. (327 aa)
OJG67621.1Hypothetical protein. (330 aa)
OJG67605.1PTS system, mannose/fructose/sorbose family, IIB component. (332 aa)
OJG67604.1PTS system, mannose/fructose/sorbose family, IIB component. (164 aa)
OJG67603.1Sigma-54 factor interaction domain-containing protein. (979 aa)
tdkThymidine kinase. (197 aa)
OJG68120.1Hypothetical protein. (287 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (340 aa)
OJG68096.1Carbamate kinase; Belongs to the carbamate kinase family. (315 aa)
OJG68079.1Hypothetical protein. (193 aa)
OJG68003.1YegS//BmrU family lipid kinase. (319 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa)
OJG67962.1Hypothetical protein. (144 aa)
OJG67892.1Hypothetical protein. (460 aa)
OJG67880.1Deoxynucleoside kinase. (213 aa)
OJG67878.1YegS//BmrU family lipid kinase. (354 aa)
OJG67869.11-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (277 aa)
OJG67844.1PTS system mannose/fructose/sorbose-specific IIB component. (156 aa)
Your Current Organism:
Enterococcus moraviensis
NCBI taxonomy Id: 155617
Other names: ATCC BAA-383, CCM 4856, CCUG 45913, CIP 107130, E. moraviensis, Enterococcus moraviensis Svec et al. 2001, LMG 19486, LMG:19486, NBRC 100710, strain 330
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