STRINGSTRING
OJG67727.1 OJG67727.1 OJG67728.1 OJG67728.1 plsX plsX OJG67742.1 OJG67742.1 OJG67338.1 OJG67338.1 OJG67344.1 OJG67344.1 purD purD purH purH purN purN purM purM purF purF purL purL purQ purQ purS purS purC purC OJG67368.1 OJG67368.1 purK purK purE purE xpt xpt OJG67408.1 OJG67408.1 coaE coaE dacA dacA prs-2 prs-2 ackA ackA OJG67278.1 OJG67278.1 OJG67279.1 OJG67279.1 OJG67286.1 OJG67286.1 pgk pgk tpiA tpiA eno eno OJG66989.1 OJG66989.1 OJG67015.1 OJG67015.1 OJG67016.1 OJG67016.1 udk udk OJG67108.1 OJG67108.1 OJG67154.1 OJG67154.1 OJG67160.1 OJG67160.1 OJG66885.1 OJG66885.1 cinA cinA OJG66942.1 OJG66942.1 OJG66943.1 OJG66943.1 OJG66739.1 OJG66739.1 ldh ldh OJG66761.1 OJG66761.1 OJG66772.1 OJG66772.1 fabZ-2 fabZ-2 OJG66823.1 OJG66823.1 deoC-2 deoC-2 deoB deoB gpmA gpmA rpiA rpiA adk adk OJG68303.1 OJG68303.1 OJG68304.1 OJG68304.1 OJG68380.1 OJG68380.1 OJG68381.1 OJG68381.1 OJG68390.1 OJG68390.1 OJG68488.1 OJG68488.1 thiI thiI ispG ispG OJG68571.1 OJG68571.1 OJG67813.1 OJG67813.1 OJG67859.1 OJG67859.1 OJG67869.1 OJG67869.1 OJG67878.1 OJG67878.1 OJG67880.1 OJG67880.1 OJG67930.1 OJG67930.1 OJG67967.1 OJG67967.1 OJG67974.1 OJG67974.1 OJG67992.1 OJG67992.1 nadK nadK OJG68000.1 OJG68000.1 OJG68003.1 OJG68003.1 gpsA gpsA deoC deoC OJG65153.1 OJG65153.1 OJG64929.1 OJG64929.1 guaB guaB OJG64737.1 OJG64737.1 OJG68180.1 OJG68180.1 guaA guaA coaA coaA add add glpK-2 glpK-2 zwf zwf folD folD OJG65687.1 OJG65687.1 OJG65771.1 OJG65771.1 lacD-3 lacD-3 lacD-2 lacD-2 OJG65736.1 OJG65736.1 lacD lacD OJG66155.1 OJG66155.1 OJG66150.1 OJG66150.1 OJG66149.1 OJG66149.1 moaA moaA moaC moaC OJG66145.1 OJG66145.1 OJG66141.1 OJG66141.1 OJG66139.1 OJG66139.1 OJG66594.1 OJG66594.1 OJG66587.1 OJG66587.1 OJG68007.1 OJG68007.1 OJG68008.1 OJG68008.1 OJG68052.1 OJG68052.1 nadE nadE atpB-2 atpB-2 atpE atpE atpF-2 atpF-2 atpH atpH atpA-2 atpA-2 atpG atpG atpD-2 atpD-2 atpC atpC OJG68071.1 OJG68071.1 OJG66586.1 OJG66586.1 OJG66585.1 OJG66585.1 nnrD nnrD OJG66698.1 OJG66698.1 tmk tmk OJG66672.1 OJG66672.1 OJG66666.1 OJG66666.1 glpK glpK OJG66637.1 OJG66637.1 nadD nadD OJG66631.1 OJG66631.1 accA accA accD accD OJG66628.1 OJG66628.1 fabZ fabZ pdhA pdhA OJG69357.1 OJG69357.1 OJG69330.1 OJG69330.1 OJG69329.1 OJG69329.1 OJG69314.1 OJG69314.1 OJG69285.1 OJG69285.1 OJG69282.1 OJG69282.1 thiM thiM thiE thiE OJG69247.1 OJG69247.1 araA araA OJG69222.1 OJG69222.1 OJG69206.1 OJG69206.1 OJG69159.1 OJG69159.1 OJG69119.1 OJG69119.1 OJG69116.1 OJG69116.1 OJG69113.1 OJG69113.1 OJG69091.1 OJG69091.1 pfkA pfkA OJG69085.1 OJG69085.1 coaD coaD OJG69071.1 OJG69071.1 OJG69056.1 OJG69056.1 guaC guaC OJG69030.1 OJG69030.1 pyrH pyrH OJG69007.1 OJG69007.1 dxr dxr pgi pgi rph rph OJG68954.1 OJG68954.1 OJG68951.1 OJG68951.1 apt apt plsY plsY OJG68879.1 OJG68879.1 ispH ispH OJG68862.1 OJG68862.1 thyA thyA OJG68837.1 OJG68837.1 cmk cmk OJG68810.1 OJG68810.1 pyrE pyrE pyrF pyrF pyrD pyrD pyrK pyrK carB carB carA carA pyrC pyrC pyrB pyrB OJG68716.1 OJG68716.1 pyrG pyrG atpD atpD atpB atpB atpA atpA OJG68674.1 OJG68674.1 OJG68610.1 OJG68610.1 OJG68605.1 OJG68605.1 OJG65362.1 OJG65362.1 OJG68079.1 OJG68079.1 OJG68096.1 OJG68096.1 OJG68099.1 OJG68099.1 OJG68116.1 OJG68116.1 tdk tdk upp upp OJG67569.1 OJG67569.1 purA purA OJG67647.1 OJG67647.1 ispF ispF ispE ispE glmU glmU OJG67682.1 OJG67682.1 prs prs OJG67706.1 OJG67706.1 gmk gmk
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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OJG67727.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
OJG67728.1Thiamine pyrophosphokinase. (209 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa)
OJG67742.1Nucleoside diphosphate kinase. (133 aa)
OJG67338.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
OJG67344.1Inositol monophosphatase. (253 aa)
purDPhosphoribosylamine-glycine ligase; Belongs to the GARS family. (421 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (507 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (195 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (346 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (454 aa)
purLPhosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (739 aa)
purQPhosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (213 aa)
purSPhosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (82 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (244 aa)
OJG67368.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (154 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa)
OJG67408.1Hypothetical protein. (159 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (295 aa)
prs-2Ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
OJG67278.1Deoxyribose-phosphate aldolase. (215 aa)
OJG67279.1RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (737 aa)
OJG67286.1Hypothetical protein. (311 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
OJG66989.1Hypothetical protein. (109 aa)
OJG67015.1Diphosphomevalonate decarboxylase. (332 aa)
OJG67016.1Phosphomevalonate kinase. (282 aa)
udkUridine kinase. (209 aa)
OJG67108.1HAD superfamily hydrolase. (218 aa)
OJG67154.1Hypothetical protein. (179 aa)
OJG67160.1Phosphoglycerate mutase. (272 aa)
OJG66885.1Hypothetical protein. (367 aa)
cinACompetence/damage-inducible protein CinA domain; Belongs to the CinA family. (415 aa)
OJG66942.1Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (184 aa)
OJG66943.1Hypothetical protein. (164 aa)
OJG66739.1Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa)
ldhL-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa)
OJG66761.1Hypothetical protein. (368 aa)
OJG66772.1Carbamate kinase; Belongs to the carbamate kinase family. (305 aa)
fabZ-2(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase 1; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa)
OJG66823.1Ribulose-phosphate 3-epimerase. (207 aa)
deoC-2Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (379 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (228 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa)
OJG68303.1Hypothetical protein. (108 aa)
OJG68304.1Hypothetical protein. (212 aa)
OJG68380.1Hypothetical protein; Belongs to the 5'-nucleotidase family. (402 aa)
OJG68381.1Hypothetical protein; Belongs to the 5'-nucleotidase family. (508 aa)
OJG68390.1Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (498 aa)
OJG68488.1Ketose-bisphosphate aldolase. (287 aa)
thiItRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (363 aa)
OJG68571.1Ribonucleoside-diphosphate reductase, class 1b, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
OJG67813.1Hypothetical protein. (134 aa)
OJG67859.1Carbamate kinase; Belongs to the carbamate kinase family. (312 aa)
OJG67869.11-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (277 aa)
OJG67878.1YegS//BmrU family lipid kinase. (354 aa)
OJG67880.1Deoxynucleoside kinase. (213 aa)
OJG67930.1Hypothetical protein. (284 aa)
OJG67967.1MutT/nudix family protein. (193 aa)
OJG67974.11-acylglycerol-3-phosphate O-acyltransferase. (201 aa)
OJG67992.1Hypothetical protein. (226 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa)
OJG68000.1Phosphoglycerate mutase. (188 aa)
OJG68003.1YegS//BmrU family lipid kinase. (319 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa)
OJG65153.1Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (482 aa)
OJG64929.1Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (321 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa)
OJG64737.16-phosphogluconolactonase. (369 aa)
OJG68180.1Hypothetical protein. (123 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (552 aa)
coaAPantothenate kinase. (315 aa)
addAdenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (335 aa)
glpK-2Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa)
folDFolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
OJG65687.1Hypothetical protein. (234 aa)
OJG65771.1Hypothetical protein; Belongs to the phosphoglycerate mutase family. (204 aa)
lacD-3Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (329 aa)
lacD-2Tagatose 1,6-diphosphate aldolase 2; Belongs to the aldolase LacD family. (335 aa)
OJG65736.11-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (312 aa)
lacDTagatose 1,6-diphosphate aldolase 2; Belongs to the aldolase LacD family. (327 aa)
OJG66155.11-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (304 aa)
OJG66150.1Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (324 aa)
OJG66149.1Molybdenum cofactor synthesis domain-containing protein. (154 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (294 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (166 aa)
OJG66145.1Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (400 aa)
OJG66141.1Hypothetical protein. (186 aa)
OJG66139.1Hypothetical protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (171 aa)
OJG66594.1HIT family protein. (142 aa)
OJG66587.1Hypothetical protein. (342 aa)
OJG68007.1Phosphopantothenoylcysteine decarboxylase. (180 aa)
OJG68008.1Phosphopantothenate-cysteine ligase. (255 aa)
OJG68052.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (490 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (275 aa)
atpB-2ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (196 aa)
atpEATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (70 aa)
atpF-2ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (175 aa)
atpHATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (165 aa)
atpA-2ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (518 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (306 aa)
atpD-2ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa)
atpCATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
OJG68071.1Hypothetical protein. (49 aa)
OJG66586.1Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. (289 aa)
OJG66585.1CDP-diacylglycerol-serine O-phosphatidyltransferase. (201 aa)
nnrDYjeF family domain-containing protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (283 aa)
OJG66698.1Hypothetical protein. (325 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
OJG66672.1Glucokinase. (323 aa)
OJG66666.1Alpha-glycerophosphate oxidase. (611 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)
OJG66637.1HD domain-containing protein. (186 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
OJG66631.1Hypothetical protein. (110 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (261 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
OJG66628.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase 2; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (139 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
OJG69357.1Dihydrolipoamide acetyltransferase. (548 aa)
OJG69330.1Citrate (Pro-3S)-lyase, beta subunit; Belongs to the HpcH/HpaI aldolase family. (288 aa)
OJG69329.1Citrate lyase, alpha subunit. (509 aa)
OJG69314.1Hypothetical protein. (280 aa)
OJG69285.1YegS//BmrU family lipid kinase. (302 aa)
OJG69282.1Hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (225 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (237 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (200 aa)
OJG69247.1Fructose-1,6-bisphosphate aldolase, class II. (288 aa)
araAL-arabinose isomerase 2; Catalyzes the conversion of L-arabinose to L-ribulose. (475 aa)
OJG69222.1Hypothetical protein. (148 aa)
OJG69206.1Ser/Thr protein phosphatase; Belongs to the 5'-nucleotidase family. (460 aa)
OJG69159.1Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (315 aa)
OJG69119.1Hypothetical protein. (241 aa)
OJG69116.1Hypothetical protein; Belongs to the phosphoglycerate mutase family. (194 aa)
OJG69113.1Hypothetical protein. (139 aa)
OJG69091.1Hypothetical protein; Belongs to the 5'-nucleotidase family. (767 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
OJG69085.1Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (146 aa)
OJG69071.1ComE operon protein 2. (169 aa)
OJG69056.1Phosphoglycerate mutase. (231 aa)
guaCGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (282 aa)
OJG69030.1Diacylglycerol kinase. (106 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
OJG69007.1Phosphatidate cytidylyltransferase; Belongs to the CDS family. (253 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (384 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (449 aa)
OJG68954.1MutT/nudix family protein; Belongs to the Nudix hydrolase family. (147 aa)
OJG68951.1HD domain-containing protein. (456 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (206 aa)
OJG68879.1Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (475 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (331 aa)
OJG68862.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (315 aa)
OJG68837.1MazG family protein. (105 aa)
cmkCytidylate kinase. (222 aa)
OJG68810.1Hypothetical protein. (172 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (167 aa)
pyrFOrotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (204 aa)
pyrDDihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (308 aa)
pyrKDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (260 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1059 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (359 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (427 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)
OJG68716.1hydroxymethylglutaryl-CoA synthase. (383 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (211 aa)
atpBV-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (443 aa)
atpAV-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (595 aa)
OJG68674.1Hypothetical protein. (193 aa)
OJG68610.1Hypothetical protein. (140 aa)
OJG68605.1Carbamate kinase; Belongs to the carbamate kinase family. (312 aa)
OJG65362.1Hypothetical protein. (167 aa)
OJG68079.1Hypothetical protein. (193 aa)
OJG68096.1Carbamate kinase; Belongs to the carbamate kinase family. (315 aa)
OJG68099.1Hypothetical protein. (193 aa)
OJG68116.1ferredoxin-NADP(+) reductase subunit alpha. (279 aa)
tdkThymidine kinase. (197 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
OJG67569.1AMP-binding protein. (509 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
OJG67647.1dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (159 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (283 aa)
glmUglmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (471 aa)
OJG67682.15-nucleotidase. (1253 aa)
prsRibose-phosphate pyrophosphokinase 1; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
OJG67706.1CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (167 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
Your Current Organism:
Enterococcus moraviensis
NCBI taxonomy Id: 155617
Other names: ATCC BAA-383, CCM 4856, CCUG 45913, CIP 107130, E. moraviensis, Enterococcus moraviensis Svec et al. 2001, LMG 19486, LMG:19486, NBRC 100710, strain 330
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