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| | atpB | V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (443 aa) |
| | OJG68607.1 | Hypothetical protein. (265 aa) |
| | OJG68668.1 | Hypothetical protein. (483 aa) |
| | OJG68674.1 | Hypothetical protein. (193 aa) |
| | atpA | V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (595 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (211 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa) |
| | OJG68714.1 | Hypothetical protein. (151 aa) |
| | OJG68716.1 | hydroxymethylglutaryl-CoA synthase. (383 aa) |
| | OJG68761.1 | Sulfatase. (697 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (427 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (359 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1059 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (260 aa) |
| | pyrD | Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (308 aa) |
| | pyrF | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (204 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (167 aa) |
| | OJG68804.1 | KH domain-containing protein; Belongs to the UPF0109 family. (82 aa) |
| | OJG68810.1 | Hypothetical protein. (172 aa) |
| | OJG68834.1 | TPR domain-containing protein. (419 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (315 aa) |
| | OJG68862.1 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (331 aa) |
| | OJG68878.1 | Hypothetical protein. (141 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | OJG68910.1 | Hypothetical protein. (145 aa) |
| | OJG68951.1 | HD domain-containing protein. (456 aa) |
| | OJG68954.1 | MutT/nudix family protein; Belongs to the Nudix hydrolase family. (147 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (277 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (384 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | OJG69056.1 | Phosphoglycerate mutase. (231 aa) |
| | OJG69057.1 | RpiR family phosphosugar-binding transcriptional regulator. (286 aa) |
| | murQ | N-acetylmuramic acid 6-phosphate etherase 2; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (295 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (146 aa) |
| | OJG69082.1 | Cell division protein FtsW; Belongs to the SEDS family. (383 aa) |
| | OJG69085.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa) |
| | OJG69097.1 | N-acetylglucosamine-6-phosphate deacetylase. (384 aa) |
| | OJG69105.1 | Hypothetical protein. (241 aa) |
| | OJG69116.1 | Hypothetical protein; Belongs to the phosphoglycerate mutase family. (194 aa) |
| | OJG69119.1 | Hypothetical protein. (241 aa) |
| | OJG69159.1 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (315 aa) |
| | OJG69173.1 | Hypothetical protein; Belongs to the SEDS family. (362 aa) |
| | araA | L-arabinose isomerase 2; Catalyzes the conversion of L-arabinose to L-ribulose. (475 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa) |
| | OJG69247.1 | Fructose-1,6-bisphosphate aldolase, class II. (288 aa) |
| | OJG69249.1 | Hypothetical protein. (257 aa) |
| | murC | UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (445 aa) |
| | OJG69300.1 | Hypothetical protein. (144 aa) |
| | OJG69304.1 | Hypothetical protein. (140 aa) |
| | OJG69314.1 | Hypothetical protein. (280 aa) |
| | OJG65674.1 | Hypothetical protein. (253 aa) |
| | OJG69329.1 | Citrate lyase, alpha subunit. (509 aa) |
| | OJG69330.1 | Citrate (Pro-3S)-lyase, beta subunit; Belongs to the HpcH/HpaI aldolase family. (288 aa) |
| | OJG69342.1 | Hypothetical protein. (404 aa) |
| | OJG69357.1 | Dihydrolipoamide acetyltransferase. (548 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase 2; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (139 aa) |
| | OJG66628.1 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (261 aa) |
| | OJG66645.1 | Hypothetical protein. (199 aa) |
| | OJG66647.1 | Hypothetical protein. (490 aa) |
| | OJG66651.1 | Penicillin-binding protein 2B. (707 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa) |
| | OJG66666.1 | Alpha-glycerophosphate oxidase. (611 aa) |
| | OJG66672.1 | Glucokinase. (323 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa) |
| | OJG66698.1 | Hypothetical protein. (325 aa) |
| | OJG66701.1 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (200 aa) |
| | dltA | D-alanine-poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] (505 aa) |
| | OJG66708.1 | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. (395 aa) |
| | dltC | D-alanine-poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (78 aa) |
| | OJG66710.1 | D-alanyl-lipoteichoic acid biosynthesis protein DltD. (423 aa) |
| | OJG66723.1 | Hypothetical protein. (341 aa) |
| | OJG66539.1 | Glucosamine-6-phosphate deaminase. (232 aa) |
| | OJG66543.1 | Hypothetical protein. (255 aa) |
| | OJG66554.1 | Hypothetical protein. (212 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L- lysine ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (506 aa) |
| | OJG66587.1 | Hypothetical protein. (342 aa) |
| | OJG65687.1 | Hypothetical protein. (234 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (321 aa) |
| | murD | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (456 aa) |
| | murG | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa) |
| | glpK-2 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa) |
| | OJG65399.1 | Hypothetical protein. (297 aa) |
| | OJG65406.1 | Glycosyl transferase, group 2 family protein. (241 aa) |
| | OJG65410.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (190 aa) |
| | OJG65411.1 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (342 aa) |
| | OJG65412.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (280 aa) |
| | OJG65134.1 | UTP-glucose-1-phosphate uridylyltransferase. (298 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa) |
| | OJG65142.1 | Pyrimidine-nucleoside phosphorylase. (431 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa) |
| | OJG64929.1 | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (321 aa) |
| | OJG64949.1 | Hypothetical protein. (555 aa) |
| | guaB | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | anmK | Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa) |
| | OJG64737.1 | 6-phosphogluconolactonase. (369 aa) |
| | OJG68180.1 | Hypothetical protein. (123 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (552 aa) |
| | coaA | Pantothenate kinase. (315 aa) |
| | OJG68233.1 | Pyrimidine-nucleoside phosphorylase. (433 aa) |
| | deoC-2 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | OJG68235.1 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (131 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (379 aa) |
| | OJG68241.1 | Inosine/guanosine/xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa) |
| | deoD | Purine nucleoside phosphorylase deoD-type. (235 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (228 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa) |
| | OJG68304.1 | Hypothetical protein. (212 aa) |
| | OJG68334.1 | Hypothetical protein. (227 aa) |
| | OJG68382.1 | Hypothetical protein. (182 aa) |
| | OJG68458.1 | Hypothetical protein. (263 aa) |
| | OJG68467.1 | Phosphosugar-binding transcriptional regulator. (251 aa) |
| | OJG68488.1 | Ketose-bisphosphate aldolase. (287 aa) |
| | OJG68496.1 | Chitinase family 2 protein; Belongs to the glycosyl hydrolase 18 family. (349 aa) |
| | OJG68497.1 | Chitin binding protein. (218 aa) |
| | OJG68504.1 | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (337 aa) |
| | OJG66154.1 | RpiR family phosphosugar-binding transcriptional regulator. (247 aa) |
| | OJG66155.1 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (304 aa) |
| | lacD | Tagatose 1,6-diphosphate aldolase 2; Belongs to the aldolase LacD family. (327 aa) |
| | OJG65726.1 | VanZ family protein. (154 aa) |
| | OJG65736.1 | 1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (312 aa) |
| | OJG65743.1 | Hypothetical protein. (394 aa) |
| | lacD-2 | Tagatose 1,6-diphosphate aldolase 2; Belongs to the aldolase LacD family. (335 aa) |
| | lacD-3 | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (329 aa) |
| | OJG65767.1 | Hypothetical protein. (395 aa) |
| | OJG65769.1 | Hypothetical protein. (336 aa) |
| | OJG65771.1 | Hypothetical protein; Belongs to the phosphoglycerate mutase family. (204 aa) |
| | gcvPA | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (438 aa) |
| | OJG65665.1 | Extracellular protein. (395 aa) |
| | OJG68532.1 | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (381 aa) |
| | mltG | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (480 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (363 aa) |
| | OJG68555.1 | Hypothetical protein. (281 aa) |
| | OJG68559.1 | Hypothetical protein. (159 aa) |
| | OJG68560.1 | Hypothetical protein. (160 aa) |
| | OJG68562.1 | Hypothetical protein. (421 aa) |
| | OJG68566.1 | Nucleotide sugar dehydrogenase. (389 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (233 aa) |
| | OJG68571.1 | Ribonucleoside-diphosphate reductase, class 1b, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa) |
| | OJG68590.1 | Hypothetical protein. (171 aa) |
| | OJG64561.1 | Hypothetical protein. (251 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (310 aa) |
| | OJG67821.1 | Acetyltransferase. (144 aa) |
| | OJG67841.1 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (229 aa) |
| | OJG67847.1 | Phosphosugar-binding protein. (346 aa) |
| | OJG67848.1 | MocD family protein; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid. (334 aa) |
| | OJG67869.1 | 1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (277 aa) |
| | OJG67955.1 | Acyltransferase. (586 aa) |
| | OJG67967.1 | MutT/nudix family protein. (193 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | OJG67992.1 | Hypothetical protein. (226 aa) |
| | OJG68000.1 | Phosphoglycerate mutase. (188 aa) |
| | OJG68007.1 | Phosphopantothenoylcysteine decarboxylase. (180 aa) |
| | OJG68008.1 | Phosphopantothenate-cysteine ligase. (255 aa) |
| | OJG68044.1 | Hypothetical protein. (559 aa) |
| | OJG68046.1 | Hypothetical protein. (340 aa) |
| | atpB-2 | ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (196 aa) |
| | atpE | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (70 aa) |
| | atpF-2 | ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (175 aa) |
| | atpH | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (165 aa) |
| | atpA-2 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (518 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (306 aa) |
| | atpD-2 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa) |
| | atpC | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | murA-2 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (432 aa) |
| | OJG68071.1 | Hypothetical protein. (49 aa) |
| | OJG68072.1 | Hypothetical protein. (209 aa) |
| | OJG68079.1 | Hypothetical protein. (193 aa) |
| | OJG68085.1 | Hypothetical protein. (345 aa) |
| | OJG68087.1 | Cobyric acid synthase. (231 aa) |
| | OJG68088.1 | Mur ligase. (445 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | OJG67569.1 | AMP-binding protein. (509 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | OJG67643.1 | Hypothetical protein. (238 aa) |
| | OJG67647.1 | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (159 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (216 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (283 aa) |
| | glmU | glmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (471 aa) |
| | prs | Ribose-phosphate pyrophosphokinase 1; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | OJG67700.1 | Hypothetical protein. (144 aa) |
| | OJG67708.1 | Hypothetical protein; Belongs to the peptidase S11 family. (476 aa) |
| | OJG67715.1 | Hypothetical protein; Belongs to the peptidase S11 family. (482 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa) |
| | OJG67727.1 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | OJG67742.1 | Nucleoside diphosphate kinase. (133 aa) |
| | OJG67338.1 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (421 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (507 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (195 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (346 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (454 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (739 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (213 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (82 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (244 aa) |
| | OJG67368.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (154 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | OJG67391.1 | Hypothetical protein. (427 aa) |
| | OJG67429.1 | Hypothetical protein. (386 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | OJG67449.1 | Hypothetical protein. (265 aa) |
| | OJG67464.1 | Hypothetical protein. (287 aa) |
| | OJG67164.1 | Hypothetical protein. (540 aa) |
| | OJG67165.1 | Hypothetical protein. (295 aa) |
| | OJG67166.1 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. (220 aa) |
| | OJG67170.1 | Hypothetical protein. (237 aa) |
| | OJG67171.1 | Hypothetical protein. (301 aa) |
| | OJG67173.1 | Hypothetical protein. (829 aa) |
| | OJG67175.1 | NAD-dependent epimerase/dehydratase. (324 aa) |
| | dacA | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (295 aa) |
| | glmS | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (606 aa) |
| | prs-2 | Ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | OJG67278.1 | Deoxyribose-phosphate aldolase. (215 aa) |
| | OJG67279.1 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (737 aa) |
| | OJG67283.1 | Hypothetical protein. (367 aa) |
| | OJG67286.1 | Hypothetical protein. (311 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | OJG66997.1 | Hypothetical protein. (240 aa) |
| | OJG67015.1 | Diphosphomevalonate decarboxylase. (332 aa) |
| | OJG67016.1 | Phosphomevalonate kinase. (282 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (230 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (346 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa) |
| | ddl | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (354 aa) |
| | udk | Uridine kinase. (209 aa) |
| | OJG67108.1 | HAD superfamily hydrolase. (218 aa) |
| | OJG67135.1 | Type 2 phosphatidic acid phosphatase. (198 aa) |
| | OJG67154.1 | Hypothetical protein. (179 aa) |
| | OJG67158.1 | Hypothetical protein. (160 aa) |
| | OJG67160.1 | Phosphoglycerate mutase. (272 aa) |
| | OJG66874.1 | Hypothetical protein. (239 aa) |
| | OJG66885.1 | Hypothetical protein. (367 aa) |
| | OJG66943.1 | Hypothetical protein. (164 aa) |
| | OJG66973.1 | Hypothetical protein. (526 aa) |
| | OJG66977.1 | Hypothetical protein. (255 aa) |
| | OJG66739.1 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa) |
| | ldh | L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa) |
| | OJG66753.1 | Iron-sulfur cluster binding protein. (381 aa) |
| | OJG66773.1 | Hypothetical protein. (158 aa) |
| | fabZ-2 | (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase 1; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa) |
| | OJG66783.1 | Hypothetical protein. (364 aa) |
| | OJG66802.1 | Hypothetical protein. (341 aa) |
| | OJG66823.1 | Ribulose-phosphate 3-epimerase. (207 aa) |
