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yhaR yhaR tdcC tdcC tdcB tdcB tdcA tdcA tdcR tdcR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yhaROrf, hypothetical protein; Residues 1 to 150 of 150 are 99.33 pct identical to residues 1 to 150 of 150 from Escherichia coli K-12 Strain MG1655: B3113. (150 aa)
tdcCAnaerobically inducible L-threonine, L-serine permease; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. (443 aa)
tdcBThreonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to [...] (329 aa)
tdcATranscriptional activator of tdc operon; Transcriptional activator for the tdcABCDE operon. Belongs to the LysR transcriptional regulatory family. (312 aa)
tdcRThreonine dehydratase operon activator protein; Residues 1 to 114 of 114 are 97.36 pct identical to residues 1 to 114 of 114 from Escherichia coli K-12 Strain MG1655: B3119. (114 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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