STRINGSTRING
htrA htrA yaeO yaeO phoE phoE tsx tsx ompF ompF ompA ompA helD helD yciD yciD ompC-2 ompC-2 ydbH ydbH ydgD ydgD ydgA ydgA asmA asmA ompC ompC yhcB yhcB yhjG yhjG yicH yicH btuB btuB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
htrAPeriplasmic serine protease Do; DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. It degrades transiently denatured and unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions. DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins. Its proteolytic activity is essen [...] (474 aa)
yaeOOrf, hypothetical protein; Residues 1 to 86 of 86 are 100.00 pct identical to residues 1 to 86 of 86 from Escherichia coli K-12 Strain MG1655: B0189. (86 aa)
phoEOuter membrane pore protein E (E,Ic,NmpAB); Residues 1 to 351 of 351 are 99.71 pct identical to residues 1 to 351 of 351 from Escherichia coli K-12 Strain MG1655: B0241; Belongs to the Gram-negative porin family. (351 aa)
tsxNucleoside channel; Functions as substrate-specific channel for nucleosides and deoxynucleosides; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (294 aa)
ompFOuter membrane protein 1a (Ia;b;F); Residues 1 to 362 of 362 are 99.44 pct identical to residues 1 to 362 of 362 from Escherichia coli K-12 Strain MG1655: B0929; Belongs to the Gram-negative porin family. (362 aa)
ompAOuter membrane protein 3a (II*;G;d); With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (346 aa)
helDDNA helicase IV; Residues 1 to 684 of 684 are 99.85 pct identical to residues 1 to 684 of 684 from Escherichia coli K-12 Strain MG1655: B0962. (684 aa)
yciDPutative outer membrane protein; Residues 1 to 212 of 212 are 96.69 pct identical to residues 1 to 212 of 212 from Escherichia coli K-12 Strain MG1655: B1256. (212 aa)
ompC-2Putative outer membrane porin protein; Residues 6 to 366 of 366 are 66.66 pct identical to residues 8 to 365 of 365 from GenPept 118 : gi|215369|gb|AAA32301.1| (J02580) outer membrane porin protein [Bacteriophage PA-2]; Belongs to the Gram-negative porin family. (366 aa)
ydbHOrf, hypothetical protein; Residues 1 to 879 of 879 are 97.95 pct identical to residues 1 to 879 of 879 from Escherichia coli K-12 Strain MG1655: B1381. (879 aa)
ydgDOrf, hypothetical protein; Residues 1 to 273 of 273 are 99.26 pct identical to residues 1 to 273 of 273 from Escherichia coli K-12 Strain MG1655: B1598; Belongs to the peptidase S1B family. (273 aa)
ydgAOrf, hypothetical protein; Residues 1 to 502 of 502 are 99.20 pct identical to residues 1 to 502 of 502 from Escherichia coli K-12 Strain MG1655: B1614. (502 aa)
asmASuppressor of ompF assembly mutants; Residues 1 to 617 of 617 are 99.51 pct identical to residues 1 to 617 of 617 from Escherichia coli K-12 Strain MG1655: B2064. (617 aa)
ompCOuter membrane protein 1b (Ib;c); Forms pores that allow passive diffusion of small molecules across the outer membrane. (367 aa)
yhcBOrf, hypothetical protein; Residues 1 to 134 of 134 are 100.00 pct identical to residues 1 to 134 of 134 from Escherichia coli K-12 Strain MG1655: B3233; To H.influenzae HI_1628. (134 aa)
yhjGOrf, hypothetical protein; Residues 1 to 691 of 691 are 99.71 pct identical to residues 1 to 691 of 691 from Escherichia coli K-12 Strain MG1655: B3524. (691 aa)
yicHOrf, hypothetical protein; Residues 1 to 569 of 569 are 98.76 pct identical to residues 1 to 569 of 569 from Escherichia coli K-12 Strain MG1655: B3655. (569 aa)
btuBOuter membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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