(6 nodes) Mixed, incl. ubiE/COQ5 methyltransferase family, and Methyltransferase domain network (Escherichia coli O157H7 EDL933)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	smtA	S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. (261 aa)
	yecD	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family. (199 aa)
	yecE	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family. (272 aa)
	yecN	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869. (141 aa)
	yecO	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa)
	yecP	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (323 aa)

Your Current Organism:

Escherichia coli O157H7 EDL933

NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
smtA	yecO	Z1268	Z2923	S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	0.826
smtA	yecP	Z1268	Z2924	S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	0.786
yecD	yecE	Z2920	Z2921	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	0.913
yecD	yecN	Z2920	Z2922	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	0.917
yecD	yecO	Z2920	Z2923	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	0.613
yecD	yecP	Z2920	Z2924	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	0.589
yecE	yecD	Z2921	Z2920	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	0.913
yecE	yecN	Z2921	Z2922	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	0.890
yecE	yecO	Z2921	Z2923	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	0.584
yecE	yecP	Z2921	Z2924	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	0.616
yecN	yecD	Z2922	Z2920	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	0.917
yecN	yecE	Z2922	Z2921	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	0.890
yecN	yecO	Z2922	Z2923	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	0.819
yecN	yecP	Z2922	Z2924	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	0.648
yecO	smtA	Z2923	Z1268	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.	0.826
yecO	yecD	Z2923	Z2920	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	Orf, hypothetical protein; Residues 1 to 199 of 199 are 100.00 pct identical to residues 1 to 199 of 199 from Escherichia coli K-12 Strain MG1655: B1867; Belongs to the isochorismatase family.	0.613
yecO	yecE	Z2923	Z2921	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	Orf, hypothetical protein; Residues 1 to 272 of 272 are 99.63 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B1868; Belongs to the UPF0759 family.	0.584
yecO	yecN	Z2923	Z2922	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	Orf, hypothetical protein; Residues 1 to 141 of 141 are 100.00 pct identical to residues 1 to 141 of 141 from Escherichia coli K-12 Strain MG1655: B1869.	0.819
yecO	yecP	Z2923	Z2924	Orf, hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	0.995
yecP	smtA	Z2924	Z1268	Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.	S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.	0.786

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