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leuO leuO yacH yacH eaeH eaeH psiF psiF rna rna ybeF ybeF abrB abrB ybhC ybhC ybhB ybhB yccT yccT Z1354 Z1354 Z1530 Z1530 grvA grvA csgG csgG csgF csgF csgE csgE csgD csgD csgB csgB csgA csgA csgC csgC ycfT ycfT Z1918 Z1918 Z1920 Z1920 ychP ychP ydcE ydcE ydcL ydcL ydcK ydcK hslJ hslJ osmB osmB ydiY ydiY fliT fliT sbmC sbmC yehR yehR Z3336 Z3336 yfaZ yfaZ yfaO yfaO yraQ yraQ yhjL yhjL Z4945 Z4945 yhjM yhjM yhjN yhjN yhjOP yhjOP Z4949 Z4949 Z4950 Z4950 yhjR yhjR yhjS yhjS yhjT yhjT yhjU yhjU yiaT yiaT yjcO yjcO yjgN yjgN iadA iadA yjiG yjiG yjiH yjiH Z5930 Z5930 yjiJ yjiJ yjjA yjjA yjjQ yjjQ bglJ bglJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
leuOProbable transcriptional activator for leuABCD operon; Residues 1 to 320 of 320 are 99.06 pct identical to residues 54 to 373 of 373 from Escherichia coli K-12 Strain MG1655: B0076; Belongs to the LysR transcriptional regulatory family. (320 aa)
yacHPutative membrane protein; Residues 1 to 617 of 617 are 96.92 pct identical to residues 1 to 617 of 617 from Escherichia coli K-12 Strain MG1655: B0117. (617 aa)
eaeHPutative adhesin; Residues 64 to 1384 of 1417 are 32.54 pct identical to residues 158 to 1460 of 2383 from GenPept 118 : gi|1788288|gb|AAC75042.1| (AE000289) putative factor [Escherichia coli]. (1417 aa)
psiFInduced by phosphate starvation; Residues 1 to 112 of 112 are 100.00 pct identical to residues 1 to 112 of 112 from Escherichia coli K-12 Strain MG1655: B0384. (112 aa)
rnaRNase I, cleaves phosphodiester bond between any two nucleotides; Residues 1 to 268 of 268 are 99.25 pct identical to residues 1 to 268 of 268 from Escherichia coli K-12 Strain MG1655: B0611; Belongs to the RNase T2 family. (268 aa)
ybeFHypothetical protein; Residues 1 to 266 of 266 are 98.87 pct identical to residues 1 to 266 of 266 from Escherichia coli K-12 Strain MG1655: B0629; Belongs to the LysR transcriptional regulatory family. (266 aa)
abrBPutative transport protein; Residues 1 to 363 of 363 are 98.07 pct identical to residues 1 to 363 of 363 from Escherichia coli K-12 Strain MG1655: B0715. (363 aa)
ybhCPutative pectinesterase; Residues 1 to 427 of 427 are 99.29 pct identical to residues 1 to 427 of 427 from Escherichia coli K-12 Strain MG1655: B0772. (427 aa)
ybhBOrf, hypothetical protein; Residues 1 to 158 of 158 are 99.36 pct identical to residues 1 to 158 of 158 from Escherichia coli K-12 Strain MG1655: B0773. (158 aa)
yccTOrf, hypothetical protein; Residues 1 to 220 of 220 are 100.00 pct identical to residues 1 to 220 of 220 from Escherichia coli K-12 Strain MG1655: B0964; Belongs to the UPF0319 family. (220 aa)
Z1354Putative endopeptidase of cryptic prophage CP-933M; Residues 1 to 155 of 155 are 100.00 pct identical to residues 1 to 155 of 155 from GenPept 118 : gi|5881639|dbj|BAA84330.1| (AP000363) Rz [Bacteriophage VT2-Sa]. (155 aa)
Z1530Hypothetical protein; Residues 12 to 160 of 163 are 29.53 pct identical to residues 7 to 152 of 154 from GenPept 118 : gi|4324611|gb|AAD16955.1| (AF106566) FidL [Salmonella typhimurium]. (163 aa)
grvAHypothetical protein; Residues 1 to 268 of 270 are 28.62 pct identical to residues 32 to 280 of 285 from GenPept 118 : gi|4324612|gb|AAD16956.1| (AF106566) putative transcriptional regulator MarT [Salmonella typhimurium]. (270 aa)
csgGCurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (277 aa)
csgFCurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (138 aa)
csgECurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (129 aa)
csgDPutative 2-component transcriptional regulator for 2nd curli operon; Residues 1 to 216 of 216 are 99.07 pct identical to residues 1 to 216 of 216 from Escherichia coli K-12 Strain MG1655: B1040. (216 aa)
csgBMinor curlin subunit precursor, similar ro CsgA; Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers (By similarity); Belongs to the CsgA/CsgB family. (151 aa)
csgACurlin major subunit, coiled surface structures; Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin; Belongs to the CsgA/CsgB family. (152 aa)
csgCPutative curli production protein; Residues 1 to 110 of 110 are 98.18 pct identical to residues 1 to 110 of 110 from Escherichia coli K-12 Strain MG1655: B1043. (110 aa)
ycfTOrf, hypothetical protein; Residues 1 to 357 of 357 are 98.87 pct identical to residues 1 to 357 of 357 from Escherichia coli K-12 Strain MG1655: B1115. (357 aa)
Z1918Putative membrane protein of prophage CP-933X; Residues 1 to 498 of 973 are 95.78 pct identical to residues 1 to 498 of 1122 from GenPept 118 : gi|1787636|gb|AAC74454.1| (AE000234) putative membrane protein [Escherichia coli]. (973 aa)
Z1920Putative tail fiber protein of prophage CP-933X; Residues 1 to 191 of 193 are 94.76 pct identical to residues 1 to 191 of 191 from GenPept 118 : gi|2367120|gb|AAC74619.1| (AE000252) orf, hypothetical protein [Escherichia coli]. (193 aa)
ychPHypothetical protein; Residues 1 to 417 of 417 are 99.52 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B1220. (417 aa)
ydcEHypothetical protein; Residues 14 to 88 of 88 are 100.00 pct identical to residues 1 to 75 of 77 from Escherichia coli K-12 Strain MG1655: B1461; Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily. (88 aa)
ydcLOrf, hypothetical protein; Residues 1 to 222 of 222 are 100.00 pct identical to residues 1 to 222 of 222 from Escherichia coli K-12 Strain MG1655: B1431. (222 aa)
ydcKOrf, hypothetical protein; Residues 1 to 326 of 326 are 98.46 pct identical to residues 1 to 326 of 326 from Escherichia coli K-12 Strain MG1655: B1428. (326 aa)
hslJHeat shock protein hslJ; Residues 1 to 140 of 140 are 99.28 pct identical to residues 1 to 140 of 140 from Escherichia coli K-12 Strain MG1655: B1379. (140 aa)
osmBOsmotically inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival (By similarity). (72 aa)
ydiYOrf, hypothetical protein; Residues 1 to 252 of 252 are 99.60 pct identical to residues 1 to 252 of 252 from Escherichia coli K-12 Strain MG1655: B1722. (252 aa)
fliTFlagellar biosynthesis; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (121 aa)
sbmCSbmC protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. (157 aa)
yehROrf, hypothetical protein; Residues 1 to 157 of 157 are 100.00 pct identical to residues 1 to 157 of 157 from Escherichia coli K-12 Strain MG1655: B2123. (157 aa)
Z3336Putative endopeptidase Rz for prophage CP-933V; Residues 1 to 155 of 155 are 98.70 pct identical to residues 1 to 155 of 155 from GenPept 118 : gi|5881639|dbj|BAA84330.1| (AP000363) Rz [Bacteriophage VT2-Sa]. (155 aa)
yfaZOrf, hypothetical protein; Residues 1 to 187 of 187 are 98.93 pct identical to residues 1 to 187 of 187 from Escherichia coli K-12 Strain MG1655: B2250. (187 aa)
yfaOOrf, hypothetical protein; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily. (141 aa)
yraQOrf, hypothetical protein; Residues 1 to 346 of 346 are 99.42 pct identical to residues 1 to 346 of 346 from Escherichia coli K-12 Strain MG1655: B3151. (346 aa)
yhjLPutative oxidoreductase subunit; Required for maximal bacterial cellulose synthesis. Belongs to the AcsC/BcsC family. (1002 aa)
Z4945Hypothetical protein; Residues 11 to 134 of 166 are 99.19 pct identical to residues 20 to 143 of 1166 from Escherichia coli K-12 Strain MG1655: B3530. (166 aa)
yhjMPutative endoglucanase; Hydrolyzes carboxymethylcellulose; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (368 aa)
yhjNOrf, hypothetical protein; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (775 aa)
yhjOPPutative cellulose synthase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix (By similarity). (888 aa)
Z4949Hypothetical protein; Residues 1 to 178 of 178 are 98.87 pct identical to residues 65 to 242 of 242 from Escherichia coli K-12 Strain MG1655: B3534. (178 aa)
Z4950Hypothetical protein; Residues 10 to 65 of 65 are 100.00 pct identical to residues 2 to 57 of 242 from Escherichia coli K-12 Strain MG1655: B3534. (65 aa)
yhjROrf, hypothetical protein; Residues 1 to 62 of 62 are 96.77 pct identical to residues 1 to 62 of 62 from Escherichia coli K-12 Strain MG1655: B3535. (62 aa)
yhjSPutative protease; Residues 1 to 523 of 523 are 99.80 pct identical to residues 1 to 523 of 523 from Escherichia coli K-12 Strain MG1655: B3536. (523 aa)
yhjTOrf, hypothetical protein; Residues 1 to 62 of 62 are 100.00 pct identical to residues 1 to 62 of 62 from Escherichia coli K-12 Strain MG1655: B3537. (62 aa)
yhjUOrf, hypothetical protein; Residues 1 to 559 of 559 are 99.46 pct identical to residues 1 to 559 of 559 from Escherichia coli K-12 Strain MG1655: B3538. (559 aa)
yiaTPutative outer membrane protein; Residues 1 to 246 of 246 are 99.18 pct identical to residues 1 to 246 of 246 from Escherichia coli K-12 Strain MG1655: B3584. (246 aa)
yjcOOrf, hypothetical protein; Residues 1 to 229 of 229 are 100.00 pct identical to residues 1 to 229 of 229 from Escherichia coli K-12 Strain MG1655: B4078. (229 aa)
yjgNOrf, hypothetical protein; Residues 19 to 407 of 407 are 96.91 pct identical to residues 5 to 393 of 393 from Escherichia coli K-12 Strain MG1655: B4257. (407 aa)
iadAIsoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. (390 aa)
yjiGOrf, hypothetical protein; Residues 1 to 153 of 153 are 100.00 pct identical to residues 1 to 153 of 153 from Escherichia coli K-12 Strain MG1655: B4329. (153 aa)
yjiHOrf, hypothetical protein; Residues 1 to 231 of 231 are 100.00 pct identical to residues 1 to 231 of 231 from Escherichia coli K-12 Strain MG1655: B4330. (231 aa)
Z5930Hypothetical protein; Residues 1 to 101 of 148 are 95.04 pct identical to residues 1 to 101 of 218 from Escherichia coli K-12 Strain MG1655: B4331. (148 aa)
yjiJPutative transport protein; Residues 1 to 387 of 392 are 90.69 pct identical to residues 1 to 387 of 392 from Escherichia coli K-12 Strain MG1655: B4332. (392 aa)
yjjAPutative glycoprotein/receptor; Residues 1 to 165 of 165 are 99.39 pct identical to residues 1 to 165 of 165 from Escherichia coli K-12 Strain MG1655: B4360. (165 aa)
yjjQPutative regulator; Residues 1 to 241 of 241 are 100.00 pct identical to residues 1 to 241 of 241 from Escherichia coli K-12 Strain MG1655: B4365. (241 aa)
bglJ2-component transcriptional regulator; Residues 1 to 225 of 225 are 100.00 pct identical to residues 1 to 225 of 225 from Escherichia coli K-12 Strain MG1655: B4366. (225 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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