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Z0415 Z0415 Z0416 Z0416 Z0417 Z0417 Z0418 Z0418 Z0419 Z0419 yneE yneE tam tam lsrG lsrG yneB yneB lsrB lsrB ydeZ ydeZ ydeY ydeY lsrA lsrA ydeW ydeW ydeV ydeV tqsA tqsA araH_B araH_B araH_A araH_A araG araG araF araF mglC mglC mglA mglA mglB mglB yphB yphB yphC_2 yphC_2 yphC_1 yphC_1 yphD yphD yphE yphE yphF yphF yphG yphG yphH yphH rbsD rbsD rbsA rbsA rbsC rbsC rbsB rbsB rbsK rbsK rbsR rbsR Z5689 Z5689 Z5690 Z5690 rbsA2 rbsA2 ytfQ ytfQ ytfR ytfR ytfT ytfT yjfF yjfF yjiS yjiS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Z0415Putative periplasmic binding protein, probable substrate ribose; Residues 16 to 324 of 328 are 27.38 pct identical to residues 15 to 335 of 340 from GenPept 118 : gi|1787795|gb|AAC74589.1| (AE000249) putative LACI-type transcriptional regulator [Escherichia coli]. (328 aa)
Z0416Putative ATP-binding component of transport system; Residues 5 to 86 of 86 are 53.65 pct identical to residues 13 to 93 of 104 from GenPept 118 : gi|5459215|emb|CAB48888.1| (AL096837) putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]. (86 aa)
Z0417Putative ATP-binding component of transport system, probably ribose specific; Residues 13 to 392 of 392 are 36.64 pct identical to residues 114 to 491 of 493 from GenPept 118 : gi|2636119|emb|CAB15611.1| (Z99122) ribose ABC transporter (ATP-binding protein) [Bacillus subtilis]. (392 aa)
Z0418Putative permease component of transport system, probably ribose specific; Residues 16 to 309 of 323 are 36.05 pct identical to residues 32 to 316 of 651 from GenPept 118 : gi|6714794|emb|CAB66286.1| (AL136519) bifunctional carbohydrate binding and transport protein. [Streptomyces coelicolor A3(2)]; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
Z0419Putative permease component of transport system, probably ribose specific; Residues 14 to 303 of 318 are 34.69 pct identical to residues 26 to 311 of 322 from GenPept 118 : gi|2636120|emb|CAB15612.1| (Z99122) ribose ABC transporter (permease) [Bacillus subtilis]; Belongs to the binding-protein-dependent transport system permease family. (318 aa)
yneEOrf, hypothetical protein; Residues 1 to 321 of 321 are 99.37 pct identical to residues 1 to 321 of 321 from Escherichia coli K-12 Strain MG1655: B1520. (321 aa)
tamPutative enzyme; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate at high affinity and of cis-aconitate, isocitrate, and citrate at lower velocities and affinities; Belongs to the methyltransferase superfamily. Tam family. (252 aa)
lsrGOrf, hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family. (96 aa)
yneBOrf, hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa)
lsrBPutative LACI-type transcriptional regulator; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity). (340 aa)
ydeZPutative transport system permease protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (330 aa)
ydeYPutative transport system permease protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (342 aa)
lsrAPutative ATP-binding component of a transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity). (511 aa)
ydeWPutative transcriptional regulator, sorC family; Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity). (317 aa)
ydeVPutative kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (530 aa)
tqsAPutative transport protein; Residues 1 to 344 of 344 are 99.12 pct identical to residues 1 to 344 of 344 from Escherichia coli K-12 Strain MG1655: B1601. (344 aa)
araH_BPartial high-affinity L-arabinose transport system; Residues 1 to 115 of 235 are 98.26 pct identical to residues 95 to 209 of 234 from Escherichia coli K-12 Strain MG1655: B1899. (235 aa)
araH_APartial high-affinity L-arabinose transport system; Residues 1 to 87 of 87 are 100.00 pct identical to residues 1 to 87 of 234 from Escherichia coli K-12 Strain MG1655: B1899. (87 aa)
araGATP-binding component of high-affinity L-arabinose transport system; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa)
araFL-arabinose-binding periplasmic protein; Residues 1 to 329 of 329 are 98.78 pct identical to residues 1 to 329 of 329 from Escherichia coli K-12 Strain MG1655: B1901. (329 aa)
mglCMethyl-galactoside transport and galactose taxis; Residues 1 to 336 of 336 are 99.70 pct identical to residues 1 to 336 of 336 from Escherichia coli K-12 Strain MG1655: B2148; Belongs to the binding-protein-dependent transport system permease family. (336 aa)
mglAATP-binding component of methyl-galactoside transport and galactose taxis; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system. (506 aa)
mglBGalactose-binding transport protein; Residues 1 to 332 of 332 are 99.69 pct identical to residues 1 to 332 of 332 from Escherichia coli K-12 Strain MG1655: B2150. (332 aa)
yphBOrf, hypothetical protein; Residues 1 to 290 of 290 are 98.96 pct identical to residues 1 to 290 of 290 from Escherichia coli K-12 Strain MG1655: B2544. (290 aa)
yphC_2Putative oxidoreductase; Residues 1 to 277 of 277 are 99.27 pct identical to residues 88 to 364 of 364 from Escherichia coli K-12 Strain MG1655: B2545. (277 aa)
yphC_1Putative oxidoreductase; Residues 1 to 74 of 74 are 98.64 pct identical to residues 1 to 74 of 364 from Escherichia coli K-12 Strain MG1655: B2545. (74 aa)
yphDPutative transport system permease protein; Residues 1 to 332 of 332 are 99.09 pct identical to residues 1 to 332 of 332 from Escherichia coli K-12 Strain MG1655: B2546; Belongs to the binding-protein-dependent transport system permease family. (332 aa)
yphEPutative ATP-binding component of a transport system; Residues 1 to 503 of 503 are 99.00 pct identical to residues 1 to 503 of 503 from Escherichia coli K-12 Strain MG1655: B2547. (503 aa)
yphFPutative LACI-type transcriptional regulator; Residues 1 to 327 of 327 are 99.08 pct identical to residues 1 to 327 of 327 from Escherichia coli K-12 Strain MG1655: B2548. (327 aa)
yphGOrf, hypothetical protein; Residues 1 to 1124 of 1124 are 98.04 pct identical to residues 1 to 1124 of 1124 from Escherichia coli K-12 Strain MG1655: B2549. (1124 aa)
yphHPutative NAGC-like transcriptional regulator; Residues 1 to 399 of 399 are 98.99 pct identical to residues 1 to 399 of 399 from Escherichia coli K-12 Strain MG1655: B2550. (399 aa)
rbsDD-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (143 aa)
rbsAATP-binding component of D-ribose high-affinity transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
rbsCD-ribose high-affinity transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane. (321 aa)
rbsBD-ribose periplasmic binding protein; Residues 1 to 296 of 296 are 99.66 pct identical to residues 1 to 296 of 296 from Escherichia coli K-12 Strain MG1655: B3751. (296 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
rbsRRegulator for rbs operon; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon (By similarity). (330 aa)
Z5689Putative periplasmic ribose-binding protein of ABC transport system; Residues 6 to 309 of 313 are 35.04 pct identical to residues 348 to 651 of 651 from GenPept 118 : gi|6714794|emb|CAB66286.1| (AL136519) bifunctional carbohydrate binding and transport protein. [Streptomyces coelicolor A3(2)]. (313 aa)
Z5690Putative permease of ribose ABC transport system; Residues 2 to 318 of 324 are 43.78 pct identical to residues 3 to 321 of 322 from GenPept 118 : gi|2636120|emb|CAB15612.1| (Z99122) ribose ABC transporter (permease) [Bacillus subtilis]; Belongs to the binding-protein-dependent transport system permease family. (324 aa)
rbsA2Putative ATP-binding protein of ribose ABC transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (517 aa)
ytfQPutative LACI-type transcriptional regulator; Residues 1 to 318 of 318 are 99.68 pct identical to residues 1 to 318 of 318 from Escherichia coli K-12 Strain MG1655: B4227. (318 aa)
ytfRPutative ATP-binding component of ABC transporter; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport. Responsible for energy coupling to the transport system. (500 aa)
ytfTPutative transport system permease protein; Residues 1 to 341 of 341 are 98.82 pct identical to residues 1 to 341 of 341 from Escherichia coli K-12 Strain MG1655: B4230; Belongs to the binding-protein-dependent transport system permease family. (341 aa)
yjfFPutative transport system permease protein; Residues 1 to 323 of 323 are 99.69 pct identical to residues 1 to 323 of 323 from Escherichia coli K-12 Strain MG1655: B4231; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
yjiSOrf, hypothetical protein; Residues 1 to 54 of 54 are 90.74 pct identical to residues 1 to 54 of 54 from Escherichia coli K-12 Strain MG1655: B4341. (54 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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