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fabA fabA fabH fabH fabD fabD fabG fabG acpP acpP fabF fabF fabI fabI fabB fabB ucpA ucpA fabF-2 fabF-2 fabG-2 fabG-2 fabF-3 fabF-3
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query proteins and first shell of interactors
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second shell of interactors
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fabABeta-hydroxydecanoyl thioester dehydrase, trans-2-decenoyl-ACP isomerase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity). (172 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. (317 aa)
fabDmalonyl-CoA-[acyl-carrier-protein] transacylase; Residues 1 to 309 of 309 are 99.35 pct identical to residues 1 to 309 of 309 from Escherichia coli K-12 Strain MG1655: B1092; Belongs to the FabD family. (309 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (78 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis (By similarity); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (413 aa)
fabIEnoyl-[acyl-carrier-protein] reductase (NADH); Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity). Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. (262 aa)
fabB3-oxoacyl-[acyl-carrier-protein] synthase I; Residues 1 to 406 of 406 are 99.50 pct identical to residues 1 to 406 of 406 from Escherichia coli K-12 Strain MG1655: B2323; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
ucpAPutative oxidoreductase; Residues 1 to 285 of 285 are 99.64 pct identical to residues 1 to 285 of 285 from Escherichia coli K-12 Strain MG1655: B2426; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
fabF-2Putative 3-oxoacyl-[ACP] synthase; Residues 4 to 384 of 389 are 31.29 pct identical to residues 8 to 403 of 407 from GenPept 118 : gi|2808747|emb|CAA16177.1| (AL021409) 3-oxoacyl-[acyl-carrier-protein] synthase [Streptomyces coelicolor A3(2)]; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (389 aa)
fabG-2Putative beta-ketoacyl-ACP reductase; Residues 1 to 242 of 243 are 57.02 pct identical to residues 1 to 241 of 242 from GenPept 118 : gi|7226957|gb|AAF42050.1| (AE002520) 3-oxoacyl-(acyl-carrier-protein) reductase [Neisseria meningitidis MC58]. (243 aa)
fabF-3Putative beta-ketoacyl-ACP synthase; Residues 3 to 408 of 409 are 55.09 pct identical to residues 2 to 412 of 414 from GenPept 118 : gi|1651213|dbj|BAA13559.1| (D88189) beta-ketoacyl-ACP synthase IV [Actinobacillus actinomycetemcomitans]; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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