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fabH fabH fabD fabD fabG fabG fabF fabF fabF-2 fabF-2 fabG-2 fabG-2 fabF-3 fabF-3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Your Input:
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. (317 aa)
fabDmalonyl-CoA-[acyl-carrier-protein] transacylase; Residues 1 to 309 of 309 are 99.35 pct identical to residues 1 to 309 of 309 from Escherichia coli K-12 Strain MG1655: B1092; Belongs to the FabD family. (309 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis (By similarity); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (413 aa)
fabF-2Putative 3-oxoacyl-[ACP] synthase; Residues 4 to 384 of 389 are 31.29 pct identical to residues 8 to 403 of 407 from GenPept 118 : gi|2808747|emb|CAA16177.1| (AL021409) 3-oxoacyl-[acyl-carrier-protein] synthase [Streptomyces coelicolor A3(2)]; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (389 aa)
fabG-2Putative beta-ketoacyl-ACP reductase; Residues 1 to 242 of 243 are 57.02 pct identical to residues 1 to 241 of 242 from GenPept 118 : gi|7226957|gb|AAF42050.1| (AE002520) 3-oxoacyl-(acyl-carrier-protein) reductase [Neisseria meningitidis MC58]. (243 aa)
fabF-3Putative beta-ketoacyl-ACP synthase; Residues 3 to 408 of 409 are 55.09 pct identical to residues 2 to 412 of 414 from GenPept 118 : gi|1651213|dbj|BAA13559.1| (D88189) beta-ketoacyl-ACP synthase IV [Actinobacillus actinomycetemcomitans]; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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