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frvA frvA sorB sorB sorF sorF sgaT sgaT ptsI ptsI crr crr murP murP srlB srlB ascF ascF ptsP ptsP cmtA cmtA cmtB cmtB Z4876 Z4876 ptsO ptsO ptsN ptsN agaB agaB Z4488 Z4488 Z4487 Z4487 agaW agaW agaV agaV fruB fruB fruA fruA fryC fryC fryB fryB ptsH ptsH fryA fryA celC celC malX malX ycgC ycgC ptsG ptsG Z1088 Z1088 Z1087 Z1087 nagE nagE Z4877 Z4877 mtlA mtlA glvC glvC frvB frvB ptsA ptsA frwB frwB frwD frwD sorA sorA yadI yadI sgaB sgaB ptxA ptxA treB treB gatA gatA gatB gatB gatC gatC manZ manZ manY manY manX manX celA celA celB celB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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frvAPTS system, fructose-specific IIA component; Residues 1 to 148 of 148 are 97.97 pct identical to residues 1 to 148 of 148 from Escherichia coli K-12 Strain MG1655: B3900. (148 aa)
sorBPutative sorbose PTS component; Residues 1 to 159 of 164 are 86.79 pct identical to residues 1 to 159 of 164 from GenPept 118 : gi|43941|emb|CAA46858.1| (X66059) EIII-B Sor PTS [Klebsiella pneumoniae]. (164 aa)
sorFPutative sorbose PTS component; Residues 1 to 135 of 135 are 71.85 pct identical to residues 1 to 135 of 135 from GenPept 118 : gi|43940|emb|CAA46857.1| (X66059) EIII-F Sor PTS [Klebsiella pneumoniae]. (135 aa)
sgaTOrf, hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (484 aa)
ptsIPEP-protein phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
crrPTS system, glucose-specific IIA component; Residues 1 to 169 of 169 are 99.40 pct identical to residues 1 to 169 of 169 from Escherichia coli K-12 Strain MG1655: B2417. (169 aa)
murPPutative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. (474 aa)
srlBPTS system, glucitol/sorbitol-specific enzyme IIA component; Residues 1 to 123 of 123 are 98.37 pct identical to residues 1 to 123 of 123 from Escherichia coli K-12 Strain MG1655: B2704. (123 aa)
ascFPTS system enzyme II ABC (asc), cryptic, transports specific beta-glucosides; Residues 1 to 485 of 485 are 97.93 pct identical to residues 1 to 485 of 485 from Escherichia coli K-12 Strain MG1655: B2715. (485 aa)
ptsPPTS system, enzyme I, transcriptional regulator (with NPR and NTR proteins); Residues 1 to 748 of 748 are 99.86 pct identical to residues 1 to 748 of 748 from Escherichia coli K-12 Strain MG1655: B2829; Belongs to the PEP-utilizing enzyme family. (748 aa)
cmtAPTS system, mannitol-specific enzyme II component, cryptic; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (462 aa)
cmtBPTS system, mannitol-specific enzyme II component, cryptic; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (147 aa)
Z4876Putative phosphotransferase system enzyme subunit; Residues 1 to 92 of 93 are 35.48 pct identical to residues 1 to 93 of 94 from GenPept 118 : gi|1788409|gb|AAC75154.1| (AE000298) galactitol-specific enzyme IIB of phosphotransferase system [Escherichia coli]. (93 aa)
ptsOPhosphocarrier protein HPr-like NPr, nitrogen related, exchanges phosphate with Enzyme I, Hpr; Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr then transfers it to EIIA-Ntr. Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins; Belongs [...] (90 aa)
ptsNPhosphotransferase system enzyme IIA, regulates N metabolism; Residues 1 to 163 of 163 are 99.38 pct identical to residues 1 to 163 of 163 from Escherichia coli K-12 Strain MG1655: B3204. (163 aa)
agaBPTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 1 (EIIB-AGA); Residues 1 to 158 of 158 are 99.36 pct identical to residues 1 to 158 of 158 from Escherichia coli K-12 Strain MG1655: B3138. (158 aa)
Z4488Putative phosphotransferase system enzyme subunit; Residues 1 to 131 of 144 are 57.25 pct identical to residues 1 to 131 of 146 from GenPept 118 : gi|1732202|gb|AAC44682.1| (U65015) PTS permease for mannose subunit IIIMan N terminal domain [Vibrio furnissii]. (144 aa)
Z4487Putative phosphotransferase system enzyme subunit; Residues 20 to 288 of 292 are 83.64 pct identical to residues 21 to 289 of 293 from GenPept 118 : gi|1732201|gb|AAC44681.1| (U65015) PTS permease for mannose subunit IIBMan [Vibrio furnissii]. (292 aa)
agaWPutative phosphotransferase system enzyme subunit; Residues 1 to 259 of 259 are 78.76 pct identical to residues 1 to 258 of 258 from GenPept 118 : gi|1732200|gb|AAC44680.1| (U65015) PTS permease for mannose subunit IIPMan [Vibrio furnissii]. (259 aa)
agaVPTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA); Residues 1 to 169 of 169 are 98.22 pct identical to residues 1 to 169 of 169 from Escherichia coli K-12 Strain MG1655: B3133. (169 aa)
fruBPTS system, fructose-specific IIA/fpr component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. (376 aa)
fruAPTS system, fructose-specific transport protein; Residues 1 to 563 of 563 are 99.46 pct identical to residues 1 to 563 of 563 from Escherichia coli K-12 Strain MG1655: B2167. (563 aa)
fryCPutative transport protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (415 aa)
fryBPutative PTS system enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport. (108 aa)
ptsHPTS system protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (85 aa)
fryAPutative PTS system enzyme IIA component, enzyme I; Multifunctional protein that includes general (non sugar- specific) and sugar-specific components of the phosphoenolpyruvate- dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport. (831 aa)
celCPEP-dependent phosphotransferase enzyme III for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2). (116 aa)
malXPTS system, maltose and glucose-specific II ABC; Residues 1 to 530 of 530 are 99.43 pct identical to residues 1 to 530 of 530 from Escherichia coli K-12 Strain MG1655: B1621. (530 aa)
ycgCPutative PTS system enzyme I; Residues 1 to 473 of 473 are 98.52 pct identical to residues 1 to 473 of 473 from Escherichia coli K-12 Strain MG1655: B1198; Belongs to the PEP-utilizing enzyme family. (473 aa)
ptsGPTS system, glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. (477 aa)
Z1088Hypothetical protein; Residues 4 to 101 of 106 are 28.57 pct identical to residues 2 to 97 of 101 from GenPept 118 : gi|1790638|gb|AAC77151.1| (AE000491) orf, hypothetical protein [Escherichia coli]. (106 aa)
Z1087Hypothetical protein; Residues 1 to 440 of 447 are 38.18 pct identical to residues 20 to 450 of 484 from GenPept 118 : gi|2367358|gb|AAC77150.1| (AE000491) orf, hypothetical protein [Escherichia coli]. (447 aa)
nagEPTS system, N-acetylglucosamine-specific enzyme IIABC; Residues 1 to 648 of 648 are 99.53 pct identical to residues 1 to 648 of 648 from Escherichia coli K-12 Strain MG1655: B0679. (648 aa)
Z4877Putative phosphotransferase system enzyme subunit; Residues 22 to 432 of 462 are 45.89 pct identical to residues 5 to 415 of 419 from GenPept 118 : gi|4512376|dbj|BAA75340.1| (AB011837) PTS system galactitol-specific enzyme IIC component [Bacillus halodurans]. (462 aa)
mtlAPTS system, mannitol-specific enzyme IIABC components; Residues 1 to 637 of 637 are 99.37 pct identical to residues 1 to 637 of 637 from Escherichia coli K-12 Strain MG1655: B3599. (637 aa)
glvCPutative PTS component; Residues 1 to 370 of 540 are 99.45 pct identical to residues 86 to 455 of 455 from Escherichia coli K-12 Strain MG1655: B3683. (540 aa)
frvBPTS system, fructose-like enzyme IIBC component; Residues 1 to 481 of 481 are 99.17 pct identical to residues 1 to 485 of 485 from Escherichia coli K-12 Strain MG1655: B3899. (481 aa)
ptsAPEP-protein phosphotransferase system enzyme I; Residues 1 to 711 of 711 are 99.57 pct identical to residues 1 to 711 of 711 from Escherichia coli K-12 Strain MG1655: B3947. (711 aa)
frwBPTS system fructose-like IIB component 1; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrwABC PTS system is involved in fructose transport. (106 aa)
frwDPTS system fructose-like IIB component 2; Residues 1 to 113 of 113 are 98.23 pct identical to residues 1 to 113 of 113 from Escherichia coli K-12 Strain MG1655: B3953. (113 aa)
sorAPutative sorbose PTS component; Residues 1 to 265 of 265 are 92.10 pct identical to residues 1 to 266 of 266 from GenPept 118 : gi|43942|emb|CAA46859.1| (X66059) first subunit of EII-Sor [Klebsiella pneumoniae]. (265 aa)
yadIPutative PTS enzyme II B component; Residues 1 to 146 of 146 are 98.63 pct identical to residues 1 to 146 of 146 from Escherichia coli K-12 Strain MG1655: B0129. (146 aa)
sgaBOrf, hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (101 aa)
ptxAPutative PTS system enzyme II A component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (154 aa)
treBPTS system enzyme II, trehalose specific; Residues 1 to 473 of 473 are 99.57 pct identical to residues 1 to 473 of 473 from Escherichia coli K-12 Strain MG1655: B4240. (473 aa)
gatAGalactitol-specific enzyme IIA of phosphotransferase system; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport. (150 aa)
gatBGalactitol-specific enzyme IIB of phosphotransferase system; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport. (94 aa)
gatCPTS system galactitol-specific enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport. (451 aa)
manZPTS enzyme IID, mannose-specific; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (286 aa)
manYPTS enzyme IIC, mannose-specific; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (266 aa)
manXPTS enzyme IIAB, mannose-specific; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (323 aa)
celAPEP-dependent phosphotransferase enzyme IV for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2). (106 aa)
celBPEP-dependent phosphotransferase enzyme II for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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