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zwf zwf hisD hisD ugd ugd gnd gnd fcI fcI wcaG wcaG gatD gatD yeiQ yeiQ yeaU yeaU ydjJ ydjJ celF celF ydiB ydiB hdhA hdhA ldhA ldhA adhP adhP sfcA sfcA uxaB uxaB ydfG ydfG ydfI ydfI adhE adhE icdA icdA fabG fabG ycdW ycdW rutE rutE ybiC ybiC ybdH ybdH ybbQ ybbQ apbA apbA ribD ribD adhC adhC yahK yahK yaeM yaeM leuB leuB pdxA pdxA thrA thrA yjjN yjjN uxuB uxuB yjgB yjgB melA melA murB murB gldA gldA metL metL yihU yihU fadB fadB wecC wecC ilvC ilvC glvA glvA tdh tdh gpsA gpsA mtlD mtlD yiaY yiaY yiaE yiaE aroE aroE mdh mdh yhaE yhaE yqhE yqhE yqhD yqhD gpr gpr serA serA kduD kduD fucO fucO guaB guaB maeB maeB eutG eutG fadJ fadJ pdxB pdxB arnA arnA
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zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
hisDL-histidinal:NAD+ oxidoreductase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
ugdUDP-glucose 6-dehydrogenase; Residues 1 to 388 of 388 are 99.22 pct identical to residues 1 to 388 of 388 from Escherichia coli K-12 Strain MG1655: B2028; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (388 aa)
gndGluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
fcIFucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
wcaGPutative nucleotide di-P-sugar epimerase or dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
gatDGalactitol-1-phosphate dehydrogenase; Converts galactitol 1-phosphate to tagatose 6-phosphate. (346 aa)
yeiQPutative oxidoreductase; Residues 1 to 488 of 488 are 98.36 pct identical to residues 1 to 488 of 488 from Escherichia coli K-12 Strain MG1655: B2172; Belongs to the mannitol dehydrogenase family. (488 aa)
yeaUPutative tartrate dehydrogenase; Residues 1 to 361 of 361 are 99.72 pct identical to residues 1 to 361 of 361 from Escherichia coli K-12 Strain MG1655: B1800. (361 aa)
ydjJPutative oxidoreductase; Residues 1 to 347 of 347 are 99.42 pct identical to residues 1 to 347 of 347 from Escherichia coli K-12 Strain MG1655: B1774. (347 aa)
celFPhospho-beta-glucosidase; Residues 1 to 450 of 450 are 98.88 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B1734. (450 aa)
ydiBPutative oxidoreductase; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD. (288 aa)
hdhANAD-dependent 7alpha-hydroxysteroid dehydrogenase, dehydroxylation of bile acids; Catalyzes the oxidation of the 7-alpha-hydroxy group of primary bile acids such as cholate. (255 aa)
ldhAFermentative D-lactate dehydrogenase, NAD-dependent; Residues 1 to 329 of 329 are 99.69 pct identical to residues 1 to 329 of 329 from Escherichia coli K-12 Strain MG1655: B1380; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
adhPAlcohol dehydrogenase; Residues 1 to 345 of 346 are 99.42 pct identical to residues 1 to 345 of 346 from Escherichia coli K-12 Strain MG1655: B1478. (346 aa)
sfcANAD-linked malate dehydrogenase (malic enzyme); Residues 1 to 574 of 574 are 99.47 pct identical to residues 1 to 574 of 574 from Escherichia coli K-12 Strain MG1655: B1479; Belongs to the malic enzymes family. (574 aa)
uxaBAltronate oxidoreductase; Residues 1 to 483 of 483 are 99.58 pct identical to residues 1 to 483 of 483 from Escherichia coli K-12 Strain MG1655: B1521; Belongs to the mannitol dehydrogenase family. UxaB subfamily. (483 aa)
ydfGPutative oxidoreductase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimidine degradation sin [...] (248 aa)
ydfIPutative oxidoreductase; Residues 1 to 486 of 486 are 98.14 pct identical to residues 1 to 486 of 486 from Escherichia coli K-12 Strain MG1655: B1542; Belongs to the mannitol dehydrogenase family. (486 aa)
adhECoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. (891 aa)
icdAIsocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136. (416 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
ycdWPutative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. (325 aa)
rutEPutative enzyme; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted; Belongs to the nitroreductase family. HadB/RutE subfamily. (196 aa)
ybiCPutative dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of 2-oxoglutarate, phenylpyruvate and (4-hydroxyphenyl)pyruvate, leading to the respective 2-hydroxycarboxylate in vitro. Shows a preference for NADPH over NADH as a redox partner. Do not catalyze the reverse reactions. (361 aa)
ybdHPutative oxidoreductase; Residues 1 to 362 of 362 are 98.89 pct identical to residues 1 to 362 of 362 from Escherichia coli K-12 Strain MG1655: B0599. (362 aa)
ybbQPutative oxidoreductase; Residues 1 to 292 of 292 are 98.97 pct identical to residues 1 to 292 of 292 from Escherichia coli K-12 Strain MG1655: B0509. (292 aa)
apbAInvolved in thiamin biosynthesis, alternative pyrimidine biosynthesis; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa)
ribDBifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
adhCAlcohol dehydrogenase class III; Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
yahKPutative oxidoreductase; Residues 1 to 349 of 349 are 99.42 pct identical to residues 1 to 349 of 349 from Escherichia coli K-12 Strain MG1655: B0325. (349 aa)
yaeMPutative ATP-binding component of a transport system; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (398 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (364 aa)
pdxAPyridoxine biosynthesis; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa)
thrAAspartokinase I, homoserine dehydrogenase I; Residues 1 to 820 of 820 are 99.75 pct identical to residues 1 to 820 of 820 from Escherichia coli K-12 Strain MG1655: B0002; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa)
yjjNPutative oxidoreductase; Residues 1 to 345 of 345 are 99.42 pct identical to residues 1 to 345 of 345 from Escherichia coli K-12 Strain MG1655: B4358. (345 aa)
uxuBMannonate oxidoreductase; Residues 1 to 486 of 486 are 99.58 pct identical to residues 1 to 486 of 486 from Escherichia coli K-12 Strain MG1655: B4323; Belongs to the mannitol dehydrogenase family. (486 aa)
yjgBPutative oxidoreductase; Residues 1 to 353 of 353 are 99.15 pct identical to residues 1 to 353 of 353 from Escherichia coli K-12 Strain MG1655: B4269. (353 aa)
melAAlpha-galactosidase; Residues 1 to 451 of 451 are 98.89 pct identical to residues 1 to 451 of 451 from Escherichia coli K-12 Strain MG1655: B4119. (451 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. (342 aa)
gldAGlycerol dehydrogenase, (NAD); Residues 1 to 380 of 380 are 99.73 pct identical to residues 1 to 380 of 380 from Escherichia coli K-12 Strain MG1655: B3945. (380 aa)
metLAspartokinase II and homoserine dehydrogenase II; Residues 1 to 810 of 810 are 99.87 pct identical to residues 1 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B3940; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa)
yihUPutative dehydrogenase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa)
fadB4-enzyme protein: 3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa)
wecCUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa)
glvAPutative 6-phospho-beta-glucosidase; Residues 1 to 440 of 440 are 75.05 pct identical to residues 1 to 441 of 441 from GenPept 118 : gi|2145152|gb|AAB63015.1| (U81185) MalH [Fusobacterium mortiferum]. (440 aa)
tdhThreonine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD+); Residues 1 to 339 of 339 are 100.00 pct identical to residues 1 to 339 of 339 from Escherichia coli K-12 Strain MG1655: B3608; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
mtlDMannitol-1-phosphate dehydrogenase; Residues 1 to 382 of 382 are 98.42 pct identical to residues 1 to 382 of 382 from Escherichia coli K-12 Strain MG1655: B3600; Belongs to the mannitol dehydrogenase family. (382 aa)
yiaYPutative oxidoreductase; Residues 1 to 381 of 383 are 98.95 pct identical to residues 1 to 381 of 382 from Escherichia coli K-12 Strain MG1655: B3589. (383 aa)
yiaEPutative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (328 aa)
aroEDehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
yhaEPutative dehydrogenase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily. (299 aa)
yqhEPutative enzyme; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). (236 aa)
yqhDPutative oxidoreductase; Residues 1 to 387 of 387 are 99.74 pct identical to residues 1 to 387 of 387 from Escherichia coli K-12 Strain MG1655: B3011. (387 aa)
gprPutative reductase; Catalyzes the stereospecific, NADPH-dependent reduction of L- glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP, which may be formed by non-enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo (By similarity). Belongs to the shaker potassium channel beta subunit family. (346 aa)
serAD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
kduD2-deoxy-D-gluconate 3-dehydrogenase; Residues 1 to 253 of 253 are 98.81 pct identical to residues 1 to 253 of 253 from Escherichia coli K-12 Strain MG1655: B2842. (253 aa)
fucOL-1,2-propanediol oxidoreductase; Residues 1 to 383 of 383 are 100.00 pct identical to residues 1 to 383 of 383 from Escherichia coli K-12 Strain MG1655: B2799. (383 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
maeBPutative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463. (759 aa)
eutGEthanolamine utilization; Residues 1 to 404 of 404 are 99.25 pct identical to residues 1 to 404 of 404 from Escherichia coli K-12 Strain MG1655: B2453. (404 aa)
fadJPutative enzyme; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (378 aa)
arnAPutative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (660 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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