STRINGSTRING
nuoG nuoG nuoC nuoC hyfB hyfB hyfD hyfD hyfG hyfG ynfH_2 ynfH_2 hycE hycE cydA cydA dmsC dmsC hyaB hyaB hyaC hyaC hycC hycC appC appC yceJ yceJ fdnI fdnI cybB cybB fdoI fdoI hybC hybC ynfH_1 ynfH_1 ydhU ydhU yodB yodB dld dld nuoN nuoN nuoM nuoM nuoL nuoL nuoK nuoK cyoC cyoC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nuoGNADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (910 aa)
nuoCNADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (600 aa)
hyfBHydrogenase 4 membrane subunit; Residues 1 to 672 of 672 are 98.95 pct identical to residues 1 to 672 of 672 from Escherichia coli K-12 Strain MG1655: B2482. (672 aa)
hyfDHydrogenase 4 membrane subunit; Residues 1 to 479 of 479 are 99.58 pct identical to residues 1 to 479 of 479 from Escherichia coli K-12 Strain MG1655: B2484. (479 aa)
hyfGHydrogenase 4 subunit; Residues 1 to 571 of 571 are 96.84 pct identical to residues 1 to 555 of 555 from Escherichia coli K-12 Strain MG1655: B2487. (571 aa)
ynfH_2Putative dimethyl sulfoxide reductase subunit C; Residues 2 to 272 of 273 are 25.26 pct identical to residues 6 to 276 of 286 from GenPept 118 : gi|5002126|gb|AAD37317.1|AF135170_8 (AF135170) dimethyl sulfoxide reductase subunit C [Yersinia pestis]. (273 aa)
hycELarge subunit of hydrogenase 3 (part of FHL complex); Residues 1 to 569 of 569 are 99.82 pct identical to residues 1 to 569 of 569 from Escherichia coli K-12 Strain MG1655: B2721. (569 aa)
cydACytochrome d terminal oxidase, polypeptide subunit I; Residues 1 to 523 of 523 are 100.00 pct identical to residues 1 to 523 of 523 from Escherichia coli K-12 Strain MG1655: B0733. (523 aa)
dmsCAnaerobic dimethyl sulfoxide reductase subunit C; Residues 1 to 287 of 287 are 98.60 pct identical to residues 1 to 287 of 287 from Escherichia coli K-12 Strain MG1655: B0896. (287 aa)
hyaBHydrogenase-1 large subunit; Residues 1 to 597 of 597 are 99.66 pct identical to residues 1 to 597 of 597 from Escherichia coli K-12 Strain MG1655: B0973; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
hyaCProbable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. (235 aa)
hycCMembrane-spanning protein of hydrogenase 3 (part of FHL complex); Residues 1 to 608 of 608 are 99.17 pct identical to residues 1 to 608 of 608 from Escherichia coli K-12 Strain MG1655: B2723. (608 aa)
appCProbable third cytochrome oxidase, subunit I; Residues 1 to 514 of 514 are 99.22 pct identical to residues 1 to 514 of 514 from Escherichia coli K-12 Strain MG1655: B0978. (514 aa)
yceJPutative cytochrome; Residues 1 to 188 of 188 are 99.46 pct identical to residues 1 to 188 of 188 from Escherichia coli K-12 Strain MG1655: B1057. (188 aa)
fdnIFormate dehydrogenase-N, nitrate-inducible, cytochrome B556(Fdn) gamma subunit; Formate dehydrogenase allows the bacterium to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. Subunit gamma is the cytochrome b556 component of the formate dehydrogenase-N, and also contains a menaquinone reduction site that receives electrons from the beta subunit (FdnH), through its hemes. Formate dehydrogenase-N is part of a system that generates proton motive force, together with the dissimilatory nitrate reductase (Nar) (By similarity). (217 aa)
cybBCytochrome b(561); Residues 1 to 188 of 188 are 99.46 pct identical to residues 1 to 188 of 188 from Escherichia coli K-12 Strain MG1655: B1418. (188 aa)
fdoIFormate dehydrogenase, cytochrome B556 (FDO) subunit; Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase (By similarity). (211 aa)
hybCProbable large subunit, hydrogenase-2; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD2 is involved in hydrogen uptake (By similarity). (567 aa)
ynfH_1Putative DMSO reductase anchor subunit; Residues 1 to 284 of 284 are 97.88 pct identical to residues 1 to 284 of 284 from Escherichia coli K-12 Strain MG1655: B1590. (284 aa)
ydhUOrf, hypothetical protein; Residues 1 to 261 of 261 are 98.08 pct identical to residues 1 to 261 of 261 from Escherichia coli K-12 Strain MG1655: B1670. (261 aa)
yodBPutative cytochrome; Residues 1 to 186 of 186 are 99.46 pct identical to residues 1 to 186 of 186 from Escherichia coli K-12 Strain MG1655: B1974. (186 aa)
dldD-lactate dehydrogenase, FAD protein, NADH independent; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa)
nuoNNADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (425 aa)
nuoMNADH dehydrogenase I chain M; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I subunit 4 family. (509 aa)
nuoLNADH dehydrogenase I chain L; Residues 1 to 613 of 613 are 99.83 pct identical to residues 1 to 613 of 613 from Escherichia coli K-12 Strain MG1655: B2278. (613 aa)
nuoKNADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Residues 1 to 204 of 204 are 99.50 pct identical to residues 1 to 204 of 204 from Escherichia coli K-12 Strain MG1655: B0430. (204 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.