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yddA yddA potA potA ycbO ycbO msbA msbA cydD cydD cydC cydC artP artP potG potG glnQ glnQ modC modC kdpA kdpA kdpB kdpB kdpC kdpC gltL gltL lapB lapB ybaR ybaR mdlB mdlB mdlA mdlA secF secF secD secD afuC afuC abc abc secA secA yabJ yabJ btuB btuB rbsA rbsA atpA atpA atpD atpD pstB pstB escN escN xylG xylG nikE nikE nikD nikD zntA zntA ugpC ugpC yhdZ yhdZ secG secG eivC eivC cysU cysU cysW cysW cysA cysA hisP hisP yojI yojI ccmA ccmA mglA mglA fliI fliI yecC yecC araG araG yebM yebM btuD btuD ycjV ycjV lsrA lsrA mgtA mgtA ytfR ytfR phnC phnC phnE phnE rbsA2 rbsA2 malK malK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
yddAPutative ATP-binding component of a transport system; Residues 1 to 561 of 561 are 99.10 pct identical to residues 1 to 561 of 561 from Escherichia coli K-12 Strain MG1655: B1496. (561 aa)
potAATP-binding component of spermidine/putrescine transport; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
ycbOOrf, hypothetical protein; Residues 1 to 333 of 333 are 97.59 pct identical to residues 1 to 333 of 333 from Escherichia coli K-12 Strain MG1655: B0936. (333 aa)
msbAATP-binding transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa)
cydDATP-binding component of cytochrome-related transport, Zn sensitive; Residues 1 to 588 of 588 are 99.31 pct identical to residues 1 to 588 of 588 from Escherichia coli K-12 Strain MG1655: B0887. (588 aa)
cydCATP-binding component of cytochrome-related transport; Residues 1 to 573 of 573 are 98.95 pct identical to residues 1 to 573 of 573 from Escherichia coli K-12 Strain MG1655: B0886. (573 aa)
artPATP-binding component of 3rd arginine transport system; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system (By similarity). (242 aa)
potGATP-binding component of putrescine transport system; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
glnQATP-binding component of glutamine high-affinity transport system; Residues 1 to 240 of 240 are 99.16 pct identical to residues 1 to 240 of 240 from Escherichia coli K-12 Strain MG1655: B0809. (240 aa)
modCATP-binding component of molybdate transport; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa)
kdpAATPase of high-affinity potassium transport system, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (557 aa)
kdpBATPase of high-affinity potassium transport system, B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCHigh-affinity potassium transport system; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (190 aa)
gltLATP-binding protein of glutamate/aspartate transport system; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for energy coupling to the transport system. (241 aa)
lapBPutative cytoplasmic membrane export protein; Residues 12 to 701 of 720 are 27.76 pct identical to residues 15 to 698 of 711 from GenPept 118 : gi|6531348|gb|AAF15371.1|U66588_3 (U66588) PaxB [Pasteurella aerogenes]. (720 aa)
ybaRPutative ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). (834 aa)
mdlBPutative ATP-binding component of a transport system; Residues 1 to 593 of 593 are 100.00 pct identical to residues 1 to 593 of 593 from Escherichia coli K-12 Strain MG1655: B0449; Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. (593 aa)
mdlAATP-binding component of a transport system; Residues 1 to 590 of 590 are 99.83 pct identical to residues 1 to 590 of 590 from Escherichia coli K-12 Strain MG1655: B0448. (590 aa)
secFProtein secretion, membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (323 aa)
secDProtein secretion; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (615 aa)
afuCPutative ATP-binding component of a transport system; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (352 aa)
abcATP-binding component of a transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
secAPreprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa)
yabJPutative ATP-binding component of a transport system; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa)
btuBOuter membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
rbsAATP-binding component of D-ribose high-affinity transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
atpAMembrane-bound ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
atpDMembrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
pstBATP-binding component of high-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)
escNescN; Residues 1 to 446 of 446 are 100.00 pct identical to residues 1 to 446 of 446 from GenPept 118 : gi|3414902|gb|AAC31513.1| (AF071034) L0034 [Escherichia coli]. (446 aa)
xylGPutative ATP-binding protein of xylose transport system; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (513 aa)
nikEATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa)
nikDATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa)
zntAZinc-transporting ATPase; Residues 1 to 732 of 732 are 98.90 pct identical to residues 1 to 732 of 732 from Escherichia coli K-12 Strain MG1655: B3469. (732 aa)
ugpCATP-binding component of sn-glycerol 3-phosphate transport system; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (369 aa)
yhdZPutative ATP-binding component of a transport system; Residues 1 to 252 of 252 are 99.20 pct identical to residues 1 to 252 of 252 from Escherichia coli K-12 Strain MG1655: B3271. (252 aa)
secGProtein export - membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity). (110 aa)
eivCType III secretion apparatus protein; Residues 10 to 396 of 439 are 63.30 pct identical to residues 1 to 386 of 432 from GenPept 118 : gi|497222|gb|AAA74038.1| (U08279) invC [Salmonella typhimurium]. (439 aa)
cysUSulfate, thiosulfate transport system permease T protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
cysWSulfate/thiosulfate transport system permease W protein; Residues 1 to 149 of 149 are 99.32 pct identical to residues 1 to 149 of 149 from Escherichia coli K-12 Strain MG1655: B2423. (149 aa)
cysAATP-binding component of sulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
hisPATP-binding component of histidine transport; Residues 1 to 257 of 257 are 99.22 pct identical to residues 1 to 257 of 257 from Escherichia coli K-12 Strain MG1655: B2306. (257 aa)
yojIPutative ATP-binding component of a transport system; Residues 1 to 547 of 547 are 99.26 pct identical to residues 1 to 547 of 547 from Escherichia coli K-12 Strain MG1655: B2211. (547 aa)
ccmAATP binding protein of heme exporter A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa)
mglAATP-binding component of methyl-galactoside transport and galactose taxis; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system. (506 aa)
fliIFlagellum-specific ATP synthase; Residues 40 to 496 of 496 are 100.00 pct identical to residues 1 to 457 of 457 from Escherichia coli K-12 Strain MG1655: B1941. (496 aa)
yecCPutative ATP-binding component of a transport system; Residues 1 to 250 of 250 are 99.59 pct identical to residues 1 to 250 of 250 from Escherichia coli K-12 Strain MG1655: B1917. (250 aa)
araGATP-binding component of high-affinity L-arabinose transport system; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa)
yebMPutative ATP-binding component of a transport system; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa)
btuDATP-binding component of vitamin B12 transport system; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
ycjVPutative ATP-binding component of a transport system; Residues 1 to 320 of 360 are 99.06 pct identical to residues 1 to 320 of 322 from Escherichia coli K-12 Strain MG1655: B1318; Belongs to the ABC transporter superfamily. (360 aa)
lsrAPutative ATP-binding component of a transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity). (511 aa)
mgtAMg2+ transport ATPase, P-type 1; Mediates magnesium influx to the cytosol; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily. (898 aa)
ytfRPutative ATP-binding component of ABC transporter; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport. Responsible for energy coupling to the transport system. (500 aa)
phnCATP-binding component of phosphonate transport; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (262 aa)
phnEMembrane channel protein component of Pn transporter; Residues 1 to 157 of 276 are 99.36 pct identical to residues 1 to 157 of 206 from Escherichia coli K-12 Strain MG1655: B4104. (276 aa)
rbsA2Putative ATP-binding protein of ribose ABC transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (517 aa)
malKATP-binding component of transport system for maltose; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (371 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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