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ada | O6-methylguanine-DNA methyltransferase; Residues 1 to 354 of 354 are 98.58 pct identical to residues 1 to 354 of 354 from Escherichia coli K-12 Strain MG1655: B2213. (354 aa) | ||||
ogt | O-6-alkylguanine-DNA/cysteine-protein methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (171 aa) |