(18 nodes) Mixed, incl. tRNA threonylcarbamoyladenosine modification, and tRNA processing network (Sphingomonas panacis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOH82970.1	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
	ybeY	rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (169 aa)
	vapC	Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (132 aa)
	AOH82973.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
	AOH82974.1	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
	miaB	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (434 aa)
	AOH82975.1	Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	fur	Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (140 aa)
	AOH82977.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
	AOH82978.1	Ribosomal-protein-alanine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
	AOH82979.1	tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
	AOH82980.1	Nitroreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
	AOH86442.1	Iron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
	AOH86443.1	Aspartyl beta-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	tsaD	tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (345 aa)
	mnmA	tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (367 aa)
	miaA	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
	AOH85438.1	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)

Your Current Organism:

Sphingomonas panacis

NCBI taxonomy Id: 1560345
Other names: JCM 30806, KCTC 42347, S. panacis, Sphingomonas panacis Singh et al. 2017, Sphingomonas sp. DCY99, strain DCY99

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOH82970.1	AOH82973.1	AWL63_02220	AWL63_02235	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
AOH82970.1	AOH82974.1	AWL63_02220	AWL63_02240	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AOH82970.1	AOH82975.1	AWL63_02220	AWL63_02250	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.620
AOH82970.1	fur	AWL63_02220	AWL63_02255	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.	0.567
AOH82970.1	miaB	AWL63_02220	AWL63_02245	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.	0.709
AOH82970.1	vapC	AWL63_02220	AWL63_02230	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.802
AOH82970.1	ybeY	AWL63_02220	AWL63_02225	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.897
AOH82973.1	AOH82970.1	AWL63_02235	AWL63_02220	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
AOH82973.1	AOH82974.1	AWL63_02235	AWL63_02240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687
AOH82973.1	vapC	AWL63_02235	AWL63_02230	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.862
AOH82973.1	ybeY	AWL63_02235	AWL63_02225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.832
AOH82974.1	AOH82970.1	AWL63_02240	AWL63_02220	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AOH82974.1	AOH82973.1	AWL63_02240	AWL63_02235	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687
AOH82974.1	AOH82975.1	AWL63_02240	AWL63_02250	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.638
AOH82974.1	AOH82977.1	AWL63_02240	AWL63_02260	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.408
AOH82974.1	AOH82979.1	AWL63_02240	AWL63_02270	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.420
AOH82974.1	fur	AWL63_02240	AWL63_02255	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.	0.649
AOH82974.1	miaB	AWL63_02240	AWL63_02245	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.	0.686
AOH82974.1	vapC	AWL63_02240	AWL63_02230	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.678
AOH82974.1	ybeY	AWL63_02240	AWL63_02225	Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.	rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.988