STRINGSTRING
AOH85075.1 AOH85075.1 queE queE AOH83972.1 AOH83972.1 AOH83971.1 AOH83971.1 AOH83940.1 AOH83940.1 nadA nadA leuC leuC leuD leuD thiG thiG aroQ aroQ AOH83896.1 AOH83896.1 AOH83895.1 AOH83895.1 AOH86619.1 AOH86619.1 AOH83874.1 AOH83874.1 AOH83873.1 AOH83873.1 AOH83857.1 AOH83857.1 AOH83842.1 AOH83842.1 AOH83841.1 AOH83841.1 AOH83793.1 AOH83793.1 AOH83712.1 AOH83712.1 fabH fabH plsX plsX proA proA pdxH pdxH gpmA gpmA ribA ribA AOH83652.1 AOH83652.1 hisC hisC bioD bioD AOH83595.1 AOH83595.1 AOH83526.1 AOH83526.1 AOH83525.1 AOH83525.1 ribB ribB ribH ribH AOH86554.1 AOH86554.1 AOH83517.1 AOH83517.1 AOH83510.1 AOH83510.1 dapF dapF argG argG AOH83484.1 AOH83484.1 AOH83482.1 AOH83482.1 AOH83470.1 AOH83470.1 queG queG panC panC AOH83441.1 AOH83441.1 aroE aroE AOH83405.1 AOH83405.1 AOH83375.1 AOH83375.1 AOH86512.1 AOH86512.1 AOH83259.1 AOH83259.1 AOH83257.1 AOH83257.1 AOH83254.1 AOH83254.1 AOH83243.1 AOH83243.1 AOH83204.1 AOH83204.1 aroC aroC AOH83187.1 AOH83187.1 AOH86484.1 AOH86484.1 AOH83181.1 AOH83181.1 AOH83162.1 AOH83162.1 AOH86478.1 AOH86478.1 acpS acpS pdxJ pdxJ AOH83086.1 AOH83086.1 AOH83083.1 AOH83083.1 thiL thiL lysA lysA argH argH hisD hisD hisG hisG coq7 coq7 tal tal AOH83013.1 AOH83013.1 AOH82960.1 AOH82960.1 AOH82946.1 AOH82946.1 AOH82896.1 AOH82896.1 AOH82862.1 AOH82862.1 tgt tgt AOH82843.1 AOH82843.1 folD folD argB argB glyA glyA AOH82817.1 AOH82817.1 pgi pgi AOH82797.1 AOH82797.1 AOH86406.1 AOH86406.1 thiC thiC ubiG ubiG AOH82782.1 AOH82782.1 AOH82751.1 AOH82751.1 AOH86400.1 AOH86400.1 AOH82750.1 AOH82750.1 AOH82747.1 AOH82747.1 AOH82726.1 AOH82726.1 putA putA AOH82719.1 AOH82719.1 kdsA kdsA AOH82665.1 AOH82665.1 AOH86374.1 AOH86374.1 AOH84002.1 AOH84002.1 argD argD AOH84014.1 AOH84014.1 proB proB AOH86640.1 AOH86640.1 queA queA AOH84035.1 AOH84035.1 bioB bioB AOH84049.1 AOH84049.1 dxs dxs AOH84063.1 AOH84063.1 queF queF mtnA mtnA mtnC mtnC mtnD mtnD mtnB mtnB AOH84146.1 AOH84146.1 asd asd AOH84183.1 AOH84183.1 AOH84192.1 AOH84192.1 proC proC AOH84197.1 AOH84197.1 AOH84219.1 AOH84219.1 AOH84225.1 AOH84225.1 AOH84251.1 AOH84251.1 dapB dapB AOH84256.1 AOH84256.1 dkgB dkgB folD-2 folD-2 AOH84385.1 AOH84385.1 AOH84416.1 AOH84416.1 hisE hisE hisF hisF hisA hisA hisH hisH hisB hisB AOH84449.1 AOH84449.1 AOH84450.1 AOH84450.1 AOH86710.1 AOH86710.1 AOH84495.1 AOH84495.1 ubiE ubiE AOH84506.1 AOH84506.1 AOH84509.1 AOH84509.1 dapE dapE AOH84550.1 AOH84550.1 apt apt AWL63_12030 AWL63_12030 AOH84597.1 AOH84597.1 panB panB serS serS mtnP mtnP AOH84710.1 AOH84710.1 AOH84761.1 AOH84761.1 AOH84777.1 AOH84777.1 cobT cobT cobS cobS AOH84782.1 AOH84782.1 cobD cobD cobQ cobQ AOH84785.1 AOH84785.1 AOH84796.1 AOH84796.1 AOH84809.1 AOH84809.1 accD accD trpA trpA trpB trpB trpF trpF aroB aroB aroK aroK accA accA dapA dapA AOH84866.1 AOH84866.1 acpP acpP AOH86783.1 AOH86783.1 argC argC hisI hisI AOH84895.1 AOH84895.1 lipA lipA AOH84918.1 AOH84918.1 pckA pckA AOH84973.1 AOH84973.1 aroA aroA AOH85022.1 AOH85022.1 AOH85047.1 AOH85047.1 AOH85048.1 AOH85048.1 cbiA cbiA AOH85051.1 AOH85051.1 AOH85052.1 AOH85052.1 AOH85053.1 AOH85053.1 AOH85054.1 AOH85054.1 AOH85055.1 AOH85055.1 AOH85056.1 AOH85056.1 cobH cobH AOH86829.1 AOH86829.1 AOH85059.1 AOH85059.1 queC queC fabZ fabZ AOH85109.1 AOH85109.1 AOH85137.1 AOH85137.1 AOH85178.1 AOH85178.1 leuD-2 leuD-2 AOH86847.1 AOH86847.1 AOH85193.1 AOH85193.1 leuC-2 leuC-2 AOH85197.1 AOH85197.1 AOH86849.1 AOH86849.1 AOH85204.1 AOH85204.1 AOH85207.1 AOH85207.1 AOH85208.1 AOH85208.1 AOH85222.1 AOH85222.1 AOH85233.1 AOH85233.1 AOH85243.1 AOH85243.1 AOH86859.1 AOH86859.1 AOH86872.1 AOH86872.1 AOH85301.1 AOH85301.1 AOH85302.1 AOH85302.1 AOH85303.1 AOH85303.1 ilvD ilvD AOH85353.1 AOH85353.1 AOH85356.1 AOH85356.1 ilvC ilvC AOH85378.1 AOH85378.1 AOH85388.1 AOH85388.1 AOH85389.1 AOH85389.1 AOH85396.1 AOH85396.1 metAA metAA metZ metZ leuB leuB AOH86899.1 AOH86899.1 carB carB carA carA asd-2 asd-2 AOH85636.1 AOH85636.1 AOH85688.1 AOH85688.1 AOH85690.1 AOH85690.1 AOH85693.1 AOH85693.1 AOH85808.1 AOH85808.1 queH queH AOH85925.1 AOH85925.1 AOH85928.1 AOH85928.1 AOH85937.1 AOH85937.1 AOH86963.1 AOH86963.1 dapF-2 dapF-2 AOH86033.1 AOH86033.1 AOH86045.1 AOH86045.1 purC purC AOH86981.1 AOH86981.1 AOH86061.1 AOH86061.1 AOH86068.1 AOH86068.1 AOH86078.1 AOH86078.1 tpiA tpiA AOH86088.1 AOH86088.1 trpD trpD trpC trpC AOH86122.1 AOH86122.1 AOH86135.1 AOH86135.1 pdxA pdxA argJ argJ dapD dapD glpX glpX thrB thrB thiE thiE ubiA ubiA AOH86220.1 AOH86220.1 AOH86240.1 AOH86240.1 AOH86250.1 AOH86250.1 AOH86262.1 AOH86262.1 glnA glnA AOH87036.1 AOH87036.1 AOH87037.1 AOH87037.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AOH85075.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
AOH83972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
AOH83971.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the membrane-bound acyltransferase family. (511 aa)
AOH83940.1Catalyzes the formation of protocatechuate from 4-hydroxybenzoate; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (331 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (266 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
AOH83896.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
AOH83895.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
AOH86619.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
AOH83874.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
AOH83873.1Phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AOH83857.1Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
AOH83842.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1000 aa)
AOH83841.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1024 aa)
AOH83793.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (396 aa)
AOH83712.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (225 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (319 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (347 aa)
proAGamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (192 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (228 aa)
ribAGTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (353 aa)
AOH83652.17, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
hisCHistidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (204 aa)
AOH83595.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
AOH83526.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (325 aa)
AOH83525.1Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (387 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (139 aa)
AOH86554.1RpsU-divergently transcribed; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AOH83517.1Cyclohexadienyl dehydrogenase; Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AOH83510.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (317 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
AOH83484.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (889 aa)
AOH83482.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (313 aa)
AOH83470.1Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
queGEpoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (374 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
AOH83441.1Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa)
AOH83405.1Thiamine monophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AOH83375.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa)
AOH86512.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AOH83259.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AOH83257.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AOH83254.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1504 aa)
AOH83243.1cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
AOH83204.1enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (359 aa)
AOH83187.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (459 aa)
AOH86484.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AOH83181.1Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AOH83162.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AOH86478.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (136 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (242 aa)
AOH83086.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
AOH83083.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (310 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa)
argHArgininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (220 aa)
coq7Ubiquinone biosynthesis protein UbiB; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (178 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (374 aa)
AOH83013.1Hydrolase Cof; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AOH82960.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AOH82946.1Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AOH82896.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (338 aa)
AOH82862.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (399 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa)
AOH82843.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (441 aa)
AOH82817.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (496 aa)
AOH82797.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (597 aa)
AOH86406.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (625 aa)
ubiGBifunctional 3-demethylubiquinol 3-O-methyltransferase/2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (240 aa)
AOH82782.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (420 aa)
AOH82751.1ATP phosphoribosyltransferase regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
AOH86400.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa)
AOH82750.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (380 aa)
AOH82747.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AOH82726.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
putADelta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1198 aa)
AOH82719.1Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (284 aa)
AOH82665.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (779 aa)
AOH86374.1Oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AOH84002.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (306 aa)
argDAcetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (397 aa)
AOH84014.1Phosphopantetheine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
AOH86640.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
AOH84035.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (358 aa)
AOH84049.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (600 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
AOH84063.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (148 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (343 aa)
mtnCEnolase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (215 aa)
mtnDCupin; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (179 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa)
AOH84146.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa)
AOH84183.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AOH84192.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
AOH84197.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
AOH84219.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AOH84225.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
AOH84251.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
AOH84256.1UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-glucuronate from UDP-glucose; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
dkgBCatalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
folD-2Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
AOH84385.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (601 aa)
AOH84416.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AOH84449.1Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (309 aa)
AOH84450.1Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (157 aa)
AOH86710.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
AOH84495.12-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
ubiEUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (243 aa)
AOH84506.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AOH84509.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (380 aa)
AOH84550.1Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (188 aa)
AWL63_12030Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (343 aa)
AOH84597.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (289 aa)
AOH84710.1Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AOH84761.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
AOH84777.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (202 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (337 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (233 aa)
AOH84782.1Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (311 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (485 aa)
AOH84785.1Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (168 aa)
AOH84796.1Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AOH84809.1Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (448 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (285 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (409 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (212 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (366 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
AOH84866.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
AOH86783.1Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (419 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa)
AOH84895.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (313 aa)
AOH84918.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa)
AOH84973.1Enterotoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (448 aa)
AOH85022.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
AOH85047.15,6-dimethylbenzimidazole synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AOH85048.1Precorrin 6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. (253 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (439 aa)
AOH85051.1Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AOH85052.1Precorrin methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
AOH85053.1precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AOH85054.1cobalt-precorrin-6A reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AOH85055.1Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AOH85056.1Catalyzes the formation of precorrin-3 from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
cobHCatalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
AOH86829.1Cobalamin biosynthesis protein CobG; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
AOH85059.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (158 aa)
AOH85109.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (246 aa)
AOH85137.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (76 aa)
AOH85178.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
leuD-23-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (204 aa)
AOH86847.13-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
AOH85193.13-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
leuC-2Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (457 aa)
AOH85197.13-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
AOH86849.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AOH85204.1Cobalamin biosynthesis protein CobY; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AOH85207.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AOH85208.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AOH85222.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AOH85233.1Gentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AOH85243.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (282 aa)
AOH86859.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AOH86872.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (998 aa)
AOH85301.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (327 aa)
AOH85302.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
AOH85303.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (196 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (573 aa)
AOH85353.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AOH85356.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AOH85378.1Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
AOH85388.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (419 aa)
AOH85389.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
AOH85396.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (402 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (350 aa)
AOH86899.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1106 aa)
carACarbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (412 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
AOH85636.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (171 aa)
AOH85688.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (253 aa)
AOH85690.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AOH85693.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (208 aa)
AOH85808.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (471 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (242 aa)
AOH85925.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AOH85928.1Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (306 aa)
AOH85937.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AOH86963.1Histone acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
dapF-2Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (266 aa)
AOH86033.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AOH86045.1Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (259 aa)
AOH86981.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (257 aa)
AOH86061.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
AOH86068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (332 aa)
AOH86078.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
AOH86088.1Anthranilate synthase; With component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (331 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (261 aa)
AOH86122.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AOH86135.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (326 aa)
argJArginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (274 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (319 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (226 aa)
ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (305 aa)
AOH86220.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
AOH86240.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AOH86250.1Inositol-3-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
AOH86262.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AOH87036.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
AOH87037.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
Your Current Organism:
Sphingomonas panacis
NCBI taxonomy Id: 1560345
Other names: JCM 30806, KCTC 42347, S. panacis, Sphingomonas panacis Singh et al. 2017, Sphingomonas sp. DCY99, strain DCY99
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