(25 nodes) HAD-like superfamily network (Sphingomonas panacis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kdpB	Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (676 aa)
	AOH87035.1	Glycerol-3-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	AOH82905.1	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (799 aa)
	AOH83013.1	Hydrolase Cof; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
	AOH83039.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
	AOH83150.1	Magnesium-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (837 aa)
	AOH83165.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (856 aa)
	AOH86492.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
	AOH83403.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	AOH83680.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	AOH83795.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	AOH83905.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (401 aa)
	phnX	Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (269 aa)
	AOH83989.1	Haloacid dehalogenase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (251 aa)
	AOH84839.1	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	AOH84710.1	Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
	AOH84623.1	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	AOH84477.1	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
	AOH84443.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	AOH84251.1	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	mtnC	Enolase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (215 aa)
	AOH86155.1	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	AOH86060.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	AOH85353.1	Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
	AOH85205.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)

Your Current Organism:

Sphingomonas panacis

NCBI taxonomy Id: 1560345
Other names: JCM 30806, KCTC 42347, S. panacis, Sphingomonas panacis Singh et al. 2017, Sphingomonas sp. DCY99, strain DCY99

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOH82905.1	AOH83795.1	AWL63_01850	AWL63_07245	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
AOH83013.1	AOH84839.1	AWL63_02475	AWL63_13570	Hydrolase Cof; Derived by automated computational analysis using gene prediction method: Protein Homology.	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.414
AOH83795.1	AOH82905.1	AWL63_07245	AWL63_01850	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
AOH84251.1	AOH84443.1	AWL63_09980	AWL63_11150	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AOH84251.1	AOH84710.1	AWL63_09980	AWL63_12780	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
AOH84443.1	AOH84251.1	AWL63_11150	AWL63_09980	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AOH84443.1	AOH84710.1	AWL63_11150	AWL63_12780	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.960
AOH84710.1	AOH84251.1	AWL63_12780	AWL63_09980	Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
AOH84710.1	AOH84443.1	AWL63_12780	AWL63_11150	Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.960
AOH84839.1	AOH83013.1	AWL63_13570	AWL63_02475	HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase Cof; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.414