STRINGSTRING
AOH82620.1 AOH82620.1 AOH82622.1 AOH82622.1 AOH82689.1 AOH82689.1 AOH82693.1 AOH82693.1 AOH82748.1 AOH82748.1 AOH82907.1 AOH82907.1 AOH82908.1 AOH82908.1 fixJ fixJ AOH82911.1 AOH82911.1 AOH82912.1 AOH82912.1 AOH86459.1 AOH86459.1 AOH83058.1 AOH83058.1 AOH83101.1 AOH83101.1 AOH83131.1 AOH83131.1 AOH86481.1 AOH86481.1 fixJ-2 fixJ-2 AOH83172.1 AOH83172.1 AOH83176.1 AOH83176.1 AOH83189.1 AOH83189.1 AOH83210.1 AOH83210.1 AOH83211.1 AOH83211.1 AOH83215.1 AOH83215.1 AOH83222.1 AOH83222.1 AOH86496.1 AOH86496.1 AOH83284.1 AOH83284.1 AOH83293.1 AOH83293.1 AOH83314.1 AOH83314.1 glnD glnD AOH83475.1 AOH83475.1 AOH83571.1 AOH83571.1 AOH83673.1 AOH83673.1 AOH83674.1 AOH83674.1 AOH83697.1 AOH83697.1 AWL63_07180 AWL63_07180 AOH83796.1 AOH83796.1 AOH83885.1 AOH83885.1 AOH83984.1 AOH83984.1 AOH83985.1 AOH83985.1 cheB cheB AOH83987.1 AOH83987.1 AOH83988.1 AOH83988.1 AOH84102.1 AOH84102.1 AOH84103.1 AOH84103.1 kdpC kdpC kdpB kdpB kdpA kdpA AOH84176.1 AOH84176.1 ctaA ctaA AOH84207.1 AOH84207.1 AOH84227.1 AOH84227.1 AOH86670.1 AOH86670.1 AOH84275.1 AOH84275.1 AOH84293.1 AOH84293.1 AOH84382.1 AOH84382.1 AOH84393.1 AOH84393.1 AOH84464.1 AOH84464.1 AOH84489.1 AOH84489.1 AOH84490.1 AOH84490.1 dnaA dnaA AOH86728.1 AOH86728.1 AOH84583.1 AOH84583.1 AOH84584.1 AOH84584.1 AOH84587.1 AOH84587.1 AOH84615.1 AOH84615.1 AOH84631.1 AOH84631.1 glsA glsA AOH84644.1 AOH84644.1 AOH84646.1 AOH84646.1 AOH84700.1 AOH84700.1 AOH84704.1 AOH84704.1 AOH84705.1 AOH84705.1 AOH84829.1 AOH84829.1 AOH84855.1 AOH84855.1 AOH84923.1 AOH84923.1 ntrC ntrC AOH84957.1 AOH84957.1 AOH86809.1 AOH86809.1 AOH85011.1 AOH85011.1 AOH85012.1 AOH85012.1 AOH85027.1 AOH85027.1 AOH85028.1 AOH85028.1 AOH85029.1 AOH85029.1 AOH85082.1 AOH85082.1 AOH85085.1 AOH85085.1 AOH85100.1 AOH85100.1 AOH85101.1 AOH85101.1 AOH85176.1 AOH85176.1 AOH86858.1 AOH86858.1 AOH85270.1 AOH85270.1 AOH85387.1 AOH85387.1 AOH85416.1 AOH85416.1 AOH85486.1 AOH85486.1 AOH85487.1 AOH85487.1 AOH85488.1 AOH85488.1 AOH85489.1 AOH85489.1 AOH85510.1 AOH85510.1 AOH85511.1 AOH85511.1 AOH85545.1 AOH85545.1 AOH85633.1 AOH85633.1 AOH85805.1 AOH85805.1 AOH85857.1 AOH85857.1 AOH85871.1 AOH85871.1 AOH85993.1 AOH85993.1 AOH86009.1 AOH86009.1 AOH86012.1 AOH86012.1 AOH86107.1 AOH86107.1 AOH86322.1 AOH86322.1 glnA glnA AOH86367.1 AOH86367.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOH82620.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (405 aa)
AOH82622.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alkaline phosphatase family. (471 aa)
AOH82689.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AOH82693.1Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AOH82748.1Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
AOH82907.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
AOH82908.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
fixJResponse regulator for histidine kinase FixL; part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
AOH82911.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (890 aa)
AOH82912.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
AOH86459.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
AOH83058.1RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (499 aa)
AOH83101.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
AOH83131.1Levansucrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 68 family. (374 aa)
AOH86481.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
fixJ-2Response regulator for histidine kinase FixL; part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AOH83172.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
AOH83176.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
AOH83189.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (339 aa)
AOH83210.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (746 aa)
AOH83211.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AOH83215.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (135 aa)
AOH83222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (319 aa)
AOH86496.1Iron dicitrate transport regulator FecR; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AOH83284.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
AOH83293.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
AOH83314.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
glnDBifunctional uridylyltransferase/uridylyl-removing protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (917 aa)
AOH83475.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AOH83571.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (516 aa)
AOH83673.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
AOH83674.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOH83697.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
AWL63_07180Glycosyl transferase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AOH83796.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (239 aa)
AOH83885.1Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
AOH83984.1Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
AOH83985.1Chemotaxis protein CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (277 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (364 aa)
AOH83987.1Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
AOH83988.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
AOH84102.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AOH84103.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (888 aa)
kdpCATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (194 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (676 aa)
kdpAPotassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (567 aa)
AOH84176.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family. (513 aa)
ctaAHeme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (349 aa)
AOH84207.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (271 aa)
AOH84227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (312 aa)
AOH86670.1Protein-tyrosine-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AOH84275.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (321 aa)
AOH84293.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (327 aa)
AOH84382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (341 aa)
AOH84393.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOH84464.1Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AOH84489.1UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (434 aa)
AOH84490.1UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (379 aa)
dnaAChromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (464 aa)
AOH86728.1Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (174 aa)
AOH84583.1Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (434 aa)
AOH84584.1Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH84587.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
AOH84615.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AOH84631.1D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (278 aa)
glsACatalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (309 aa)
AOH84644.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
AOH84646.1Histidine phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AOH84700.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AOH84704.1Phosphate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
AOH84705.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AOH84829.1Citrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (293 aa)
AOH84855.1Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)
AOH84923.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ntrCNitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (472 aa)
AOH84957.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
AOH86809.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AOH85011.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AOH85012.1Ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AOH85027.1Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (424 aa)
AOH85028.1Multidrug transporter; Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1036 aa)
AOH85029.1Nodulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1098 aa)
AOH85082.1Pectin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AOH85085.1Iron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AOH85100.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
AOH85101.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)
AOH85176.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AOH86858.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
AOH85270.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AOH85387.1Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AOH85416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (279 aa)
AOH85486.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
AOH85487.1Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AOH85488.1Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (767 aa)
AOH85489.1Histidine phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AOH85510.1Cytochrome d ubiquinol oxidase subunit 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
AOH85511.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
AOH85545.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AOH85633.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (357 aa)
AOH85805.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AOH85857.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (460 aa)
AOH85871.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
AOH85993.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
AOH86009.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (316 aa)
AOH86012.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (370 aa)
AOH86107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AOH86322.1Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AOH86367.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
Your Current Organism:
Sphingomonas panacis
NCBI taxonomy Id: 1560345
Other names: JCM 30806, KCTC 42347, S. panacis, Sphingomonas panacis Singh et al. 2017, Sphingomonas sp. DCY99, strain DCY99
Server load: low (28%) [HD]