STRINGSTRING
AQM59947.1 AQM59947.1 AQM60550.1 AQM60550.1 AQM58785.1 AQM58785.1 ung ung queG queG nth nth AQM59903.1 AQM59903.1 AQM59338.1 AQM59338.1 xth xth NPD11_598 NPD11_598 NPD11_599 NPD11_599 nfo nfo NPD11_601 NPD11_601 NPD11_602 NPD11_602 NPD11_603 NPD11_603 NPD11_604 NPD11_604 NPD11_605 NPD11_605 NPD11_606 NPD11_606 NPD11_607 NPD11_607 NPD11_608 NPD11_608 nfo-2 nfo-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQM59947.1methylated-DNA--[]-cysteine S-methyltransferase family protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (154 aa)
AQM60550.1Patatin-like phospholipase family protein; [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily. (296 aa)
AQM58785.1Amidohydrolase family protein; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (531 aa)
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa)
queGEpoxyqueuosine reductase; [C] COG1600 Uncharacterized Fe-S protein. (330 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa)
AQM59903.1eamA-like transporter family protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (291 aa)
AQM59338.1eamA-like transporter family protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (296 aa)
xthexoDNase_III: exodeoxyribonuclease III; [L] COG0708 Exonuclease III. (251 aa)
NPD11_598Hypothetical protein. (225 aa)
NPD11_599Hypothetical protein. (116 aa)
nfoApurinic endonuclease family protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (278 aa)
NPD11_601hhH-GPD superbase excision DNA repair family protein; [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (293 aa)
NPD11_602Hypothetical protein; dnaB-like helicase N terminal domain protein; [L] COG0305 Replicative DNA helicase. (426 aa)
NPD11_603Conserved phage family protein. (251 aa)
NPD11_604Hypothetical protein. (61 aa)
NPD11_605Conserved hypothetical protein; [S] COG3689 Predicted membrane protein. (246 aa)
NPD11_606Putative permease family protein; [R] COG0701 Predicted permeases. (301 aa)
NPD11_607cobW/HypB/UreG, nucleotide-binding domain protein; [R] COG0523 Putative GTPases (G3E family). (216 aa)
NPD11_608cobW/HypB/UreG, nucleotide-binding domain protein; [R] COG0523 Putative GTPases (G3E family). (323 aa)
nfo-2Apurinic endonuclease family protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (306 aa)
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.