(51 nodes) Mixed, incl. Periplasmic binding protein, and ABC transporter, permease network (Streptomyces sp. CCMMD2014)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIV32257.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
	AIV38467.1	Oxetanocin A resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	AIV32563.1	RNA polymerase sigma 70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (309 aa)
	AIV32564.1	GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
	AIV32565.1	Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	AIV32566.1	LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
	AIV32567.1	L-rhamnose mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
	AIV32568.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
	AIV32569.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (337 aa)
	AIV32570.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (346 aa)
	rbsA	D-ribose transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (505 aa)
	AIV32572.1	Rhamnose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
	AIV32573.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
	AIV32574.1	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
	AIV32831.1	Myo-inositol 2-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
	AIV32832.1	LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
	AIV32833.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
	AIV32835.1	2-keto-myo-inositol dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
	AIV32836.1	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
	AIV32837.1	Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (358 aa)
	AIV32838.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
	AIV32839.1	5-dehydro-2-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
	AIV32840.1	Deoxyribose-phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
	AIV32841.1	5-deoxyglucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
	AIV32842.1	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (624 aa)
	AIV32843.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
	AIV33057.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	AIV33058.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (339 aa)
	AIV33059.1	Sugar ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
	AIV33441.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
	AIV33442.1	Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (346 aa)
	AIV33443.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
	AIV33445.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
	AIV33615.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
	AIV33667.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (430 aa)
	AIV33668.1	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
	AIV33669.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
	AIV35165.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
	rbsD	Ribose ABC transporter; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (129 aa)
	rbsK	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (300 aa)
	AIV36356.1	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (652 aa)
	rbsA-2	Sugar ABC transporter ATPase; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (508 aa)
	AIV36678.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
	AIV36680.1	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (414 aa)
	AIV36681.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
	AIV36682.1	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
	AIV36683.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
	AIV36684.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
	AIV36685.1	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (388 aa)
	AIV36686.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	iolG	Inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (339 aa)

Your Current Organism:

Streptomyces sp. CCMMD2014

NCBI taxonomy Id: 1561022
Other names: S. sp. CCM_MD2014, Streptomyces sp. CCM_MD2014

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIV32257.1	AIV32567.1	NI25_00935	NI25_02685	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	L-rhamnose mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.670
AIV32257.1	AIV32568.1	NI25_00935	NI25_02690	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AIV32257.1	AIV32569.1	NI25_00935	NI25_02695	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.980
AIV32257.1	AIV32570.1	NI25_00935	NI25_02700	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.977
AIV32257.1	AIV32572.1	NI25_00935	NI25_02710	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhamnose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
AIV32257.1	AIV32573.1	NI25_00935	NI25_02715	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.626
AIV32257.1	AIV32574.1	NI25_00935	NI25_02720	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.617
AIV32257.1	AIV32836.1	NI25_00935	NI25_04275	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.567
AIV32257.1	AIV32837.1	NI25_00935	NI25_04280	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.605
AIV32257.1	AIV33058.1	NI25_00935	NI25_05560	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.689
AIV32257.1	AIV33059.1	NI25_00935	NI25_05565	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.616
AIV32257.1	AIV33441.1	NI25_00935	NI25_07995	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.567
AIV32257.1	AIV33442.1	NI25_00935	NI25_08000	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.600
AIV32257.1	AIV33667.1	NI25_00935	NI25_09310	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.405
AIV32257.1	AIV33668.1	NI25_00935	NI25_09315	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.629
AIV32257.1	AIV33669.1	NI25_00935	NI25_09320	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
AIV32257.1	AIV35165.1	NI25_00935	NI25_18000	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.437
AIV32257.1	AIV36356.1	NI25_00935	NI25_25150	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.591
AIV32257.1	AIV36681.1	NI25_00935	NI25_27070	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.635
AIV32257.1	rbsA	NI25_00935	NI25_02705	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	D-ribose transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.	0.956