STRINGSTRING
AIV32320.1 AIV32320.1 AIV32822.1 AIV32822.1 AIV33469.1 AIV33469.1 acnA acnA AIV33795.1 AIV33795.1 AIV33796.1 AIV33796.1 pckG pckG mdh mdh gabD2 gabD2 AIV34822.1 AIV34822.1 AIV34823.1 AIV34823.1 acsA acsA AIV35856.1 AIV35856.1 ppc ppc AIV36377.1 AIV36377.1 AIV37780.1 AIV37780.1 AIV37945.1 AIV37945.1 AIV37946.1 AIV37946.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIV32320.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa)
AIV32822.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
AIV33469.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (540 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AIV33795.1Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (390 aa)
AIV33796.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (606 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
AIV34822.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
AIV34823.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
AIV35856.1Citrate synthase 2; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (366 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (911 aa)
AIV36377.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
AIV37780.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AIV37945.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
AIV37946.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (479 aa)
Your Current Organism:
Streptomyces sp. CCMMD2014
NCBI taxonomy Id: 1561022
Other names: S. sp. CCM_MD2014, Streptomyces sp. CCM_MD2014
Server load: low (14%) [HD]