(22 nodes) AMP-binding, conserved site network (Streptomyces sp. CCMMD2014)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIV33500.1	AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
	AIV33745.1	Peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (532 aa)
	AIV32786.1	Enterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
	AIV32853.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
	AIV33074.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)
	AIV33726.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
	AIV32283.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3668 aa)
	AIV32766.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2169 aa)
	AIV32767.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (1051 aa)
	AIV32768.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (3073 aa)
	AIV32784.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1856 aa)
	AIV32785.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2230 aa)
	AIV37608.1	acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
	AIV36936.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
	AIV36631.1	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
	AIV36539.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (625 aa)
	AIV36389.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
	AIV35852.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
	AIV35457.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
	acsA	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
	AIV34887.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
	AIV38643.1	AMP-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)

Your Current Organism:

Streptomyces sp. CCMMD2014

NCBI taxonomy Id: 1561022
Other names: S. sp. CCM_MD2014, Streptomyces sp. CCM_MD2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIV32283.1	AIV32766.1	NI25_01080	NI25_03840	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.612
AIV32283.1	AIV32767.1	NI25_01080	NI25_03845	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.628
AIV32283.1	AIV32768.1	NI25_01080	NI25_03855	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
AIV32283.1	AIV32784.1	NI25_01080	NI25_03970	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.463
AIV32283.1	AIV32785.1	NI25_01080	NI25_03975	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.721
AIV32283.1	AIV32786.1	NI25_01080	NI25_03980	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
AIV32283.1	AIV33745.1	NI25_01080	NI25_09775	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.437
AIV32766.1	AIV32283.1	NI25_03840	NI25_01080	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.612
AIV32766.1	AIV32767.1	NI25_03840	NI25_03845	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.988
AIV32766.1	AIV32768.1	NI25_03840	NI25_03855	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
AIV32766.1	AIV32784.1	NI25_03840	NI25_03970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
AIV32766.1	AIV32785.1	NI25_03840	NI25_03975	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.982
AIV32766.1	AIV32786.1	NI25_03840	NI25_03980	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
AIV32766.1	AIV32853.1	NI25_03840	NI25_04365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.596
AIV32766.1	AIV33500.1	NI25_03840	NI25_08350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
AIV32766.1	AIV33726.1	NI25_03840	NI25_09670	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.597
AIV32766.1	AIV33745.1	NI25_03840	NI25_09775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.657
AIV32766.1	AIV35457.1	NI25_03840	NI25_19690	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
AIV32766.1	AIV35852.1	NI25_03840	NI25_22175	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.588
AIV32766.1	AIV36631.1	NI25_03840	NI25_26805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.612