(23 nodes) ClpP/crotonase-like domain superfamily network (Streptomyces sp. CCMMD2014)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIV34037.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	AIV34109.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	AIV34373.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
	AIV34516.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
	AIV34519.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
	AIV38775.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
	AIV35849.1	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
	AIV35853.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
	AIV35964.1	Peptidase S41; Degrades oligopeptides; Belongs to the peptidase S41B family. (1151 aa)
	AIV36149.1	Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
	AIV36322.1	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
	clpP-2	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (219 aa)
	clpP	Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (237 aa)
	AIV36549.1	Peptidase S41; Degrades oligopeptides; Belongs to the peptidase S41B family. (1067 aa)
	AIV36630.1	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
	AIV37210.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
	clpP-3	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (200 aa)
	AIV37659.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	AIV32914.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	AIV32926.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
	AIV33658.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa)
	AIV33700.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
	clpP-4	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (217 aa)

Your Current Organism:

Streptomyces sp. CCMMD2014

NCBI taxonomy Id: 1561022
Other names: S. sp. CCM_MD2014, Streptomyces sp. CCM_MD2014

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIV32914.1	AIV33658.1	NI25_04695	NI25_09250	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.405
AIV32914.1	AIV37659.1	NI25_04695	NI25_32530	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
AIV32926.1	AIV33658.1	NI25_04755	NI25_09250	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
AIV32926.1	AIV34037.1	NI25_04755	NI25_11540	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV32926.1	AIV34519.1	NI25_04755	NI25_14280	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
AIV32926.1	AIV35849.1	NI25_04755	NI25_22160	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.623
AIV32926.1	AIV35853.1	NI25_04755	NI25_22180	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.934
AIV32926.1	AIV36322.1	NI25_04755	NI25_24975	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.954
AIV32926.1	AIV36630.1	NI25_04755	NI25_26800	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.553
AIV32926.1	AIV38775.1	NI25_04755	NI25_19000	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV33658.1	AIV32914.1	NI25_09250	NI25_04695	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.405
AIV33658.1	AIV32926.1	NI25_09250	NI25_04755	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
AIV33658.1	AIV34037.1	NI25_09250	NI25_11540	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV33658.1	AIV34519.1	NI25_09250	NI25_14280	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV33658.1	AIV35849.1	NI25_09250	NI25_22160	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV33658.1	AIV36322.1	NI25_09250	NI25_24975	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
AIV33658.1	AIV36630.1	NI25_09250	NI25_26800	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.553
AIV33658.1	AIV37210.1	NI25_09250	NI25_30020	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.615
AIV33658.1	AIV37659.1	NI25_09250	NI25_32530	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.463
AIV33658.1	AIV38775.1	NI25_09250	NI25_19000	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558